Expression and characterization of recombinant single-chain Fv and Fv fragments derived from a set of catalytic antibodies

Molecular Immunology

Volumn 34, Issue 12-13, 1997, Pages 891-906

  Kim, Se Ho ^a   Schindler, Daniel G ^a   Lindner, Ariel B ^a   Tawfik, Dan S ^a,b   Eshhar, Zelig ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Catalytic antibodies; Expression of antibody fragments; Fv fragments; Immunoglobulin genes; Kinetic parameters; Refolding; Single chain antibody

Indexed keywords

IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN LIGHT CHAIN;

ANTIGEN BINDING; ARTICLE; CATALYSIS; ENZYME LINKED IMMUNOSORBENT ASSAY; ESCHERICHIA COLI; IMMUNOGLOBULIN GENE; IMMUNOGLOBULIN VARIABLE REGION; KINETICS; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; ANTIBODIES, CATALYTIC; BASE SEQUENCE; CATALYSIS; CLONING, MOLECULAR; ESCHERICHIA COLI; GENETIC VECTORS; IMMUNOGLOBULIN FRAGMENTS; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN LIGHT CHAINS; IMMUNOGLOBULIN VARIABLE REGION; KINETICS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN FOLDING; RECOMBINANT PROTEINS; RESTRICTION MAPPING; STRUCTURE-ACTIVITY RELATIONSHIP;

ESCHERICHIA COLI;

EID: 0031424583     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0161-5890(97)00096-5     Document Type: Article

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