Substrate- and pH-dependent contribution of oxyanion binding site to the catalysis of prolyl oligopeptidase, a paradigm of the serine oligopeptidase family

Protein Science

Volumn 9, Issue 2, 2000, Pages 353-360

  Szeltner, Zoltán ^a   Renner, Veronika ^a   Polgár, László ^a  

^a INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

Author keywords

Amnesia; Inhibitor design; Oxyanion binding site; Site directed mutagenesis; Steady state kinetic studies; Transition state stabilization

Indexed keywords

COMPLEMENTARY DNA; PROLYL ENDOPEPTIDASE; RECOMBINANT PROTEIN;

AMNESIA; ARTICLE; BINDING SITE; CATALYSIS; ENZYME KINETICS; ENZYME SUBSTRATE; ESCHERICHIA COLI; HYDROLYSIS; NONHUMAN; PH; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS; STEADY STATE;

ESCHERICHIA COLI; FELIS CATUS;

EID: 0034003936     PISSN: 09618368     EISSN: None     Source Type: Journal    
DOI: 10.1110/ps.9.2.353     Document Type: Article

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