c-fos induction in rat superficial dorsal horn following cutaneous application of noxious chemical or mechanical stimuli

Experimental Brain Research

Volumn 145, Issue 2, 2002, Pages 261-269

  Jinks, Steven L ^a,b,c   Simons, Christopher T ^a,b,c   Dessirier, Jean Marc ^a,b,c   Carstens, Mirela ^a,b,c   Antognini, Joseph F ^a,b,c   Carstens, E ^a,b,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNILEVER RESEARCH   (United Kingdom)

Author keywords

c fos; Cutaneous; Itch; Pain; Rat; Spinal cord; Superficial dorsal horn

Indexed keywords

CAPSAICIN; FORMALDEHYDE; HISTAMINE; IRRITANT AGENT; METHYLCELLULOSE; NICOTINE; PROTEIN C FOS; SEROTONIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CELL COUNT; CONTROLLED STUDY; IMMUNODETECTION; IMMUNOREACTIVITY; IONTOPHORESIS; LUMBAR SPINAL CORD; MALE; MECHANICAL STIMULATION; MICROINJECTION; NOCICEPTIVE STIMULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN INDUCTION; PROTEIN LOCALIZATION; RAT; SPINAL CORD DORSAL HORN; SPINAL CORD NERVE CELL;

ADMINISTRATION, CUTANEOUS; ANIMALS; IONTOPHORESIS; IRRITANTS; MALE; MICROINJECTIONS; PHYSICAL STIMULATION; POSTERIOR HORN CELLS; PROTO-ONCOGENE PROTEINS C-FOS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0036305928     PISSN: 00144819     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00221-002-1128-3     Document Type: Article

References (96)

1. Differential contribution of the two phases of the formalin test to the pattern of c-fos expression in the rat spinal cord: Studies with remifentanil and lidocaine
2. Spinothalamic lamina I neurons selectively sensitive to histamine: A central neural pathway for itch
3. Physiology and morphology of substantia gelatinosa neurons intracellularly stained with horseradish peroxidase
4. 1D-like receptor involved in serotonergic induced hindlimb scratching in rats
5. Differences in opioidergic inhibition of spinal reflexes and Fos expression evoked by mechanical and chemical noxious stimuli in the decerebrated rabbit
6. Somatotopy of spinal nociceptive processing
7. The effect of stimulus duration on noxious-stimulus induced c-fos expression in the rodent spinal cord
8. The contribution of GABAB receptor-mediated events to inflammatory pain processing: Carrageenan oedema and associated spinal c-Fos expression in the rat
9. An opioidergic cortical antinociception triggering site in the agranular insular cortex of the rat that contributes to morphine antinociception
10. Dopamine reuptake inhibition in the rostral agranular insular cortex produces antinociception
11. Changes in formalin-evoked spinal Fos expression and nociceptive behaviour after oral administration of Bufferin A (aspirin) and L-5409709 (ibuprofen + caffeine + paracetamol)
12. Responses of rat spinal dorsal horn neurons to intracutaneous microinjection of histamine, capsaicin and other irritants
13. Brain stem neurons signaling expressing c-fos immunoreactivity following chemical stimulation of the rat's tongue
14. Activation of neurons in rat trigeminal subnucleus caudalis by different irritant chemicals applied to oral or ocular mucosa
15. Baclofen and midazolam alter c-fos induction by peripheral noxious or innocuous stimulation in the spinal cord of normal and mono-arthritic rats
16. Effects of opioid receptor antagonists on the effects of i.v. morphine on carrageenan evoked c-Fos expression in the superficial dorsal horn of the rat spinal cord
17. An electrophysiological study of neurones in the substantia gelatinosa Rolandi of the cat's spinal cord
18. The contribution of NMDA receptor activation to spinal c-Fos expression in a model of inflammatory pain
19. Spinal neurons specifically excited by noxious or thermal stimuli: Marginal zone of the dorsal horn
20. Oral irritant effects of nicotine: Psychophysical evidence for decreased sensation following repeated application and lack of cross-desensitization with capsaicin
21. Intradermal 5-HT induces Fos expression in rat dorsal horn neurons not via 5-HT3 but by via 5-HT2 A receptors
22. Pruritis in polycythaemia vera: Treatment with aspirin and possibility of platelet involvement
23. Is substance P a primary afferent neurotransmitter for nociceptive input? I. Analysis of pain-related behaviors resulting from intrathecal administration of substance P and 6 excitatory compounds
24. Long ascending projections from substantia gelatinosa Rolandi and the subjacent dorsal horn in the rat
25. Enhanced withdrawal responses to heat and mechanical stimuli following intraplantar injection of capsaicin in rats
26. Inhibition of carrageenan-induced spinal c-Fos activation by systemically administered c-fos antisense oligodeoxynucleotides may be facilitated by local opening of the blood-spinal cord barrier
27. Pre- versus postinjury effects of intravenous GABAergic anesthetics on formalin-induced Fos immunoreactivity in the rat spinal cord
28. Inhibition of noxious stimulus-evoked pain behaviors and neuronal fos-like immunoreactivity in the spinal cord of the rat by supraspinal morphine
29. Differential contribution of descending controls to the antinociceptive actions of kappa and mu opioids: An analysis of formalin-evoked C-fos expression
30. Mast cells and mast cell products
31. Cytofluorometric analysis of anaphylactic secretion of 5-hydroxytryptamine and heparin from rat mast cells
32. Itch mediators
33. Differential effects of intrathecally administered delta and mu opioid receptor agonists on formalin-evoked nociception and on the expression of Fos-like immunoreactivity in the spinal cord of the rat
34. Using c-fos as a neural marker of pain
35. Inducible and constitutive transcription factors in the mammalian nervous system: Control of gene expression by Jun, Fos and Krox, and CREB/ATF proteins
36. Activation of c-fos in the brain
37. Chronic treatment with systemic morphine induced tolerance to the systemic and peripheral antinociceptive effects of morphine on both carrageenan induced mechanical hyperalgesia and spinal c-Fos expression in awake rats
38. Protein synthesis inhibitor cycloheximide dose-dependently decreases formalin-induced c-Fos protein and behavioral hyperalgesia in rats
39. Induction of c-fos-like protein in spinal cord neurons following sensory stimulation
40. Phosphorylation of transcription factor CREB in rat spinal cord after formalin-induced hyperalgesia: Relationship to c-fos induction
41. Endomorphin-1 reduces carrageenan-induced fos expression in the rat spinal dorsal horn
42. Spinal NMDA receptor involvement in the expansion of mechanosensitive receptive field area of dorsal horn neurons produced by intracutaneous microinjection of histamine
43. Activation of spinal wide dynamic range neurons by intracutaneous microinjection of nicotine
44. Superficial dorsal horn neurons identified using intracutaneous histamine as a search stimulus: Chemonociceptive responses and modulation by morphine
45. Responses of superficial dorsal horn neurons to intradermal serotonin and other irritants: Comparison with scratching behavior
46. Scratching behavior induced by pruritogenic but not algesiogenic agents in mice
47. Neurogenic hyperalgesia: Psychophysical studies of underlying mechanisms
48. Effect of acute stimulation on Fos expression in spinal neurons in the presence of persisting C-fiber activity
49. Effects of NMDA receptor antagonists on morphine tolerance: A c-Fos study in the lumbar spinal cord of the rat
50. Spinal terminations of functionally identified primary afferent neurons with slowly conducting myelinated fibers
51. Morphological features of functionally defined neurons in the marginal zone and substantia gelatinosa of the spinal dorsal horn
52. Spinal c-fos expression is differentially induced by brief or persistent noxious stimulation
53. Neurons in the substantia gelatinosa rolandi (lamina II) project to the caudal ventrolateral reticular formation of the medulla oblongata in the rat
54. The spino-latero-reticular system of the rat: Projections from the superficial dorsal horn and structural characterization of marginal neurons involved
55. Differential activation of c-fos in spinal neurones by distinct classes of noxious stimuli
56. Spatial and temporal expression of c-Fos protein in the spinal cord of anesthetized rat induced by subcutaneous bee venom injection
57. Spinal cannabinoids are anti-allodynic in rats with persistent inflammation
58. Expression of c-fos protein in interneurons and projection neurons of the rat spinal cord in response to noxious somatic, articular, and visceral stimulation
59. Transcription factor regulation of prodynorphin gene expression following rat hindpaw inflammation
60. Cutaneous projections from the rat hindlimb foot to the substantia gelatinosa of the spinal cord studied by transganglionic transport of WGA-HRP conjugate
61. Laminar distribution and somatotopic organization of primary afferent fibers from hindlimb nerves in the dorsal horn. A study by transganglionic transport of horseradish peroxidase in the rat
62. The differential contribution of capsaicin-sensitive afferents to behavioral and cardiovascular measures of brief and persistent nociception and to Fos expression in the formalin test
63. Comparison of histamine and 5-hydroxytryptamine content and secretion in rat mast cells isolated from different anatomical locations
64. A nitric oxide synthesis inhibitor (L-NAME) reduces licking behavior and Fos-labeling in the spinal cord of rats during formalin-induced inflammation
65. The contribution of supraspinal, peripheral and intrinsic spinal circuits to the pattern and magnitude of Fos-like immunoreactivity in the lumbar spinal cord of the rat withdrawing from morphine
66. Transdermal nicotine facilitates smoking cessation
67. Fos-like immunoreactivity induced by intraplantar injection of endotoxin and its reduction by morphine
68. Opioidergic and adrenergic modulation of formalin-evoked spinal c-fos mRNA expression and nocifensive behavior in the rat
69. Modulated expression of c-Fos in the spinal cord following noxious thermal stimulation of monoarthritic rats
70. Specific C-receptors for itch in human skin
71. The magnitude and duration of itch produced by intracutaneous injections of histamine
72. Psychophysical studies of the itch sensation and itchy skin ("allokinesis") produced by intracutaneous injection of histamine
73. Receptor mediation of 5-HT-induced inflammation and nociception in rats
74. Central projections of identified, unmyelinated (C) afferent fibers innervating mammalian skin
75. The somatotopic organization of primary afferent terminals in the superficial laminae of the dorsal horn of the rat spinal cord
76. A contribution of neurokinin-1 receptor to formalin-induced c-fos expression in the rat spinal dorsal horn
77. Neurons in the superficial dorsal horn of the rat spinal cord projecting to the medullary ventrolateral reticular formation express c-fos after noxious stimulation of the skin
78. Effects of local anaesthesia on formalin-induced Fos expression in the rat dorsal horn
79. 2A receptor subtype is involved in the thermal hyperalgesic mechanism of serotonin in the periphery
80. Suppression of noxious stimulus-evoked expression of Fos protein-like immunoreactivity in rat spinal cord by a selective cannabinoid agonist
81. Inflammation-induced Fos protein expression in the rat spinal cord is enhanced following dorsolateral or ventrolateral funiculus lesions
82. Can a serotonin type 3 (5-HT3) receptor antagonist reduce experimentally induced itch?
83. Changing patterns of c-fos induction in spinal neurons following thermal cutaneous stimulation in the rat
84. Spinothalamic tract neurons in the substantia gelationsa
85. Somatotopic organization of cutaneous afferent terminals and dorsal horn neuronal receptive fields in the superficial and deep laminae of the rat lumbar spinal cord
86. Fos expression is induced by increased nitric oxide release in rat spinal cord dorsal horn
87. 2 receptors in mice
88. Inhibitory effect of intrathecally administered nociceptin on the expression of Fos-like immunoreactivity in the rat formalin test
89. Knee joint inflammation attenuates spinal FOS expression after unilateral paw formalin injection in rat
90. Histamine-caused itch induces Fos-like immunoreactivity in dorsal horn neurons: Effect of morphine pretreatment
91. Comparison of the effects of treatment with intrathecal lidocaine given before and after formalin on both nociception and Fos expression in the spinal cord dorsal horn
92. c-Fos expression in NMDA receptor-contained neurons in spinal cord in a rat model of inflammation: A double immunocytochemical study
93. Control of gene transcription by Jun and Fos proteins in the nervous system: Beneficial or harmful molecular mechanisms of neuronal response to noxious stimulation?