Fos-like immunoreactivity induced by intraplantar injection of endotoxin and its reduction by morphine

Brain Research

Volumn 769, Issue 1, 1997, Pages 57-65

  E Saadé, Nayef ^a   Abou Jaoude, Pamela G ^a   Saadeh, Faysal A ^a   Hamoui, Samar ^b   Safieh Garabedian, Bared ^a   Kanaan, Salim A ^a   Atweh, Samir F ^a   Jabbur, Suhayl J ^a  

^a AMERICAN UNIVERSITY OF BEIRUT   (Lebanon)

^b LEBANESE UNIVERSITY   (Lebanon)

Author keywords

C fos protein; Dorsal horn; Endotoxin; Hyperalgesia; Inflammatory pain; Opioid; Pain test

Indexed keywords

ENDOTOXIN; MORPHINE; PROTEIN C FOS;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; GENE EXPRESSION; HYPERALGESIA; IMMUNOREACTIVITY; INFLAMMATION; INTRAMUSCULAR DRUG ADMINISTRATION; INTRAPERITONEAL DRUG ADMINISTRATION; LUMBAR SPINAL CORD; MYELITIS; NEUROTOXICITY; NONHUMAN; ONCOGENE C FOS; PAIN ASSESSMENT; PLANTARIS MUSCLE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

ANALGESICS, OPIOID; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTOXINS; FOOT; HYPERALGESIA; IMMUNOHISTOCHEMISTRY; INJECTIONS; LUMBOSACRAL REGION; MORPHINE; NEURONS; PROTO-ONCOGENE PROTEINS C-FOS; RATS; RATS, SPRAGUE-DAWLEY; SPINAL CORD; TIME FACTORS; TISSUE DISTRIBUTION;

EID: 0342813160     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(97)00662-8     Document Type: Article

References (42)

1. Abbadie C., Besson J.-M. c-fos expression in rat lumbar spinal cord during the development of adjuvant-induced arthritis. Neuroscience. 48:1992;985-993.
2. Abbadie C., Besson J.-M. Effects of morphine and naloxone on basal and evoked Fos-like immunoreactivity in lumbar spinal cord neurons of arthritic rats. Pain. 52:1993;29-39.
3. Atweh S.F., Kuhar M.J. Autoradiographic localization of opiate receptors in rat brain. I. Spinal cord and lower medulla Brain Res. 124:1977;53-67.
4. Atweh S.F., Murin C.L., Kuhar M.J. Presynaptic localization of opiate receptors in the vagal and accessory optic systems: an autoradiographic study. Neuropharmacology. 17:1978;65-71.
5. Bertolucci M., Perego C., De Simoni M.G. Central opiate modulation of peripheral IL-6 in rats. NeuroReport. 7:1996;1181-1184.
6. Bullitt E. Expression of c-fos-like protein as a marker for neuronal activity following noxious stimulation in the rat. J. Comp. Neurol. 296:1990;517-530.
7. Bullitt E. Induction of c-fos-like protein within the lumbar spinal cord and thalamus of the rat following peripheral stimulation. Brain Res. 493:1989;391-397.
8. Curran T., Morgan J.I. Superinduction of c-fos by nerve growth factor in the presence of peripherally active benzodiazepines. Science. 229:1985;1265-1268.
9. Draisci G., Iadarola M.J. Temporal analysis of increases in c-fos, preprodynorphin and preproenkephalin mRNAs in rat spinal cord. Mol. Brain Res. 6:1989;31-37.
10. Elmquist J.K., Scammell T.E., Jacobson C.D., Saper C.B. Distribution of Fos-like immunoreactivity in the rat brain following intravenous lipopolysaccharide administration. J. Comp. Neurol. 371:1996;85-103.
11. Herdegen T., Kovary K., Leah J., Bravo R. Specific temporal and spatial distribution of JUN, FOS, and KROX-24 proteins in spinal neurons following noxious transsynaptic stimulation. J. Comp. Neurol. 313:1991;178-191.
12. Hermanson O., Blomqvist A. Subnuclear localization of FOS-like immunoreactivity in the rat parabrachial nucleus after nociceptive stimulation. J. Comp. Neurol. 368:1996;45-56.
13. Honoré P., Chapman V., Buritova J., Besson J.-M. When is the maximal effect of pre-administered systemic morphine on carrageenin evoked spinal c-Fos expression in the rat? Brain Res. 705:1995;91-96.
14. Hsu S., Raine L., Fanger H. Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabelled antibody (PAP) procedures. J. Histochem. Cytochem. 29:1981;577-580.
15. Hunt S.P., Pini A., Evan G. Induction of c-fos-like protein in spinal cord neurons following sensory stimulation. Nature. 328:1987;632-634.
16. Hylden J.L.K., Noguchi K., Ruda M.A. Neonatal capsaicin treatment attenuates spinal Fos activation and dynorphin gene expression following peripheral tissue inflammation and hyperalgesia. J. Neurosci. 12:1992;1716-1725.
17. Kanaan S.A., Saadé N.E., Haddad J.J., Abdelnoor A.M., Atweh S.F., Jabbur S.J., Safieh-Garabedian B. Endotoxin-induced local inflammation and hyperalgesia in rats and mice: a new model for inflammatory pain. Pain. 66:1996;373-379.
18. Lima D., Avelino A., Coimbra A. Differential activation of c-fos in spinal neurones by distinct classes of noxious stimuli. NeuroReport. 4:1993;747-750.
19. Maier S.F., Wiertelak E.P., Goehler L., Martin D., Watkins L.R. Interleukin-1 mediates the behavioral hyperalgesia produced by lithium chloride and endotoxin. Brain Res. 623:1993;321-325.
20. Menétrey D., Gannon A., Levine J.D., Basbaum A.I. Expression of c-fos protein in interneurons and projection neurons of the rat spinal cord in response to noxious somatic, articular, and visceral stimulation. J. Comp. Neurol. 285:1989;177-195.
21. Munglani R., Fleming B.G., Hunt S.P. Remembrance of times past: the significance of c-fos in pain. Br. J. Anaesth. 76:1996;1-4.
22. Naranjo J.R., Mellström B., Achaval M., Sassone-Corsi P. Molecular pathways of pain: Fos/Jun-mediated activation of a noncanonical AP-1 site in the prodynorphin gene. Neuron. 6:1991;607-617.
23. Noguchi K., Dubner R., Ruda M.A. Preproenkephalin mRNA in spinal dorsal horn neurons is induced by peripheral inflammation and is colocalized with Fos and Fos-related proteins. Neuroscience. 46:1992;561-570.
24. G. Paxinos, C. Watson, The Rat Brain in Stereotaxic Coordinates, 2nd edn., Academic Press, New York, 1986.
25. Presley R.W., Menétrey D., Levine J.D., Basbaum A.I. Systemic morphine suppresses noxious stimulus-evoked Fos protein-like immunoreactivity in the rat spinal cord. J. Neurosci. 10:1990;323-335.
26. Przewlocki R., Hassan A.H.S., Lason W., Epplen C., Herz A., Stein C. Gene expression and localization of opioid peptides in immune cells of inflamed tissue: functional role in antinociception. Neuroscience. 48:1992;491-500.
27. N.E. Saadé, S.A. Kanaan, J.J. Haddad, S.F. Atweh, S.J. Jabbur, B. Safieh-Garabedian, Dissociation between peripheral and central components of the endotoxin-induced hyperalgesia, Symposium on the Application of the Theory of Metablic Regulation to Pain, September 23-29, 1996, in press.
28. 2 in endotoxin induced localized inflammatory hyperalgesia, Br. J. Pharmacol., in press.
29. Sagar S.M., Price K.J., Kasting N.W., Sharp F.R. Anatomic patterns of FOS immunostaining in rat brain following systemic endotoxin administration. Brain Res. Bull. 36:1995;381-392.
30. Schäfer M., Carter L., Stein C. Interleukin 1β and corticotropin-releasing factor inhibit pain by releasing opioids from immune cells in inflamed tissue. Proc. Natl. Acad. Sci. USA. 91:1994;4219-4223.
31. Schäfer M., Mousa S.A., Zhang Q., Carter L., Stein C. Expression of corticotropin-releasing factor in inflamed tissue is required for intrinsic peripheral opioid analgesia. Proc. Natl. Acad. Sci. USA. 93:1996;6096-6100.
32. Sehic E., Blatteis C.M. Blockade of lipopolysaccharide-induced fever by subdiaphragmatic vagotomy in guinea pigs. Brain Res. 726:1996;160-166.
33. C. Stein, The control of pain in peripheral tissue by opioids, in: F.H. Epstein (Ed.), Mechanisms of Disease, N. Engl. J. Med., 332 (1995) 1685-1689.
34. Strassman A.M., Vos B.P., Mineta Y., Naderi S., Borsook D., Burstein R. Fos-like immunoreactivity in the superficial medullary dorsal horn induced by noxious and innocuous thermal stimulation of facial skin in the rat. J. Neurosci. 70:1993;1811-1821.
35. Tkacs N.C., Strack A.M. Systemic endotoxin induces Fos-like immunoreactivity in rat spinal sympathetic regions. J. Auton. Nerv. Syst. 51:1995;1-7.
36. M. Tohyama, H. Kiyama, K. Satoh, T. Araki, H. Maeno, H. Oyamada, E. Kondo, Glutaminergic neurotransmission, proto-oncogenes, and pain, in: G.F. Gebhart, D.L. Hammond, T.S. Jensen (Eds.), Progress in Pain Research and Management, Vol. 2, IASP Press, Seattle, 1994, pp. 395-409.
37. Tölle T.R., Herdegen T., Schadrack J., Bravo R., Zimmermann M., Zieglgänsberger W. Application of morphine prior to noxious stimulation differentially modulates expression of Fos, Jun and Krox-24 proteins in rat spinal cord neurons. Neuroscience. 58:1994;305-321.
38. Traub R.J., Pechman P., Iadarola M.J., Gebhart G.F. Fos-like proteins in the lumbosacral spinal cord following noxious and non-noxious colorectal distention in the rat. Pain. 49:1992;393-403.
39. Wan W., Wetmore L., Sorensen C.M., Greenberg A.H., Nance D.M. Neural and biochemical mediators of endotoxin and stress-induced c-fos expression in the rat brain. Brain Res. 34:1994;7-14.
40. Watkins L.R., Wiertelak E.P., Goehler L., Mooney-Heiberger K., Martinez J., Furness L., Smith K.P., Maier S.F. Neurocircuitry of illness-induced hyperalgesia. Brain Res. 639:1994;283-299.
41. Watkins L.R., Wiertelak E.P., Goehler L.E., Smith K.P., Martin D., Maier S.F. Characterization of cytokine-induced hyperalgesia. Brain Res. 654:1994;15-26.
42. Zimmerman M. Ethical guidelines for investigations of experimental pain in conscious animals. Pain. 16:1983;109-110.