Spatial and temporal expression of c-Fos protein in the spinal cord of anesthetized rat induced by subcutaneous bee venom injection

Brain Research

Volumn 806, Issue 2, 1998, Pages 175-185

  Luo, Ceng ^a   Chen, Jun ^a   Li, Hui Li ^a   Li, Ji Shuo ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

c Fos expression; Central change; Dorsal horn; Immunohistochemistry; Morphine; Persistent pain; Rat; Subcutaneous bee venom injection

Indexed keywords

BEE VENOM; PROTEIN C FOS;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BEE STING; CONTROLLED STUDY; IMMUNOHISTOCHEMISTRY; MALE; NOCICEPTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SPINAL CORD DORSAL HORN; TISSUE DISTRIBUTION;

ANALGESICS, OPIOID; ANIMALS; BEE VENOMS; BEHAVIOR, ANIMAL; IMMUNOHISTOCHEMISTRY; INJECTIONS, SUBCUTANEOUS; MALE; MORPHINE; NEURONS; PROTO-ONCOGENE PROTEINS C-FOS; RATS; RATS, SPRAGUE-DAWLEY; SPINAL CORD; TIME FACTORS; TISSUE DISTRIBUTION;

EID: 0032576015     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(98)00721-5     Document Type: Article

References (40)

1. Abbadie C., Besson J.-M. c-fos expression in rat lumbar spinal cord during the development of adjuvant-induced arthritis. Neuroscience. 48:1992;985-993.
2. Abbadie C., Taylor B.K., Peterson M.A., Basbaum A.I. Differential contribution of the two phases of the formalin test to the pattern of c-fos expression in the spinal cord: studies with remifentanil and lidocaine. Pain. 69:1997;101-110.
3. Bontempi B., Sharp F.R. Systemic morphine-induced Fos protein in the rat striatum and nucleus accumbens is regulated by μ opioid receptors in the substantia nigra and ventral tegmental area. J. Neurosci. 17:1997;8596-8612.
4. A.G. Brown (Ed.), Organization in the Spinal Cord, Springer-Verlag, Berlin, 1981.
5. Bullitt E. Somatotopy of spinal nociceptive processing. J. Comp. Neurol. 312:1991;279-290.
6. Chapman V., Buritova J., Honore P., Besson J.M. Physiological contribution of neurokinin 1 receptor activation, and interactions with NMDA receptors, to inflammatory-evoked spinal c-Fos expression. J. Neurophysiol. 76:1996;1817-1827.
7. Chen J., Koyama N. Effects of subcutaneous formalin on responses of identified primary afferent units in the cat: an electrophysiological study. Chin. J. Neuroanat. 12:1996;381-393.
8. Chen J., Koyama N. Differential activation of spinal dorsal horn units by subcutaneous formalin injection in the cat: an electrophysiological study. Exp. Brain Res. 118:1998;14-18.
9. Chen J., Koyama N., Yokota T. Effects of subcutaneous formalin on responses of dorsal horn wide dynamic range neurons and primary afferent neurons in the cat. Pain Res. 11:1996;71-83.
10. Chen J., Luo C., Li H.-L. Long-lasting increase in spinal wide-dynamic-range neuron discharges induced by subcutaneous injection of bee venom in the cat. A comparison with subcutaneous formalin injection. Chin. J. Neuroanat. 13(Suppl):1997;p76.
11. Dallel R., Raboisson P., Clavelou P., Saade M., Woda A. Evidence for a peripheral origin of the tonic nociceptive response to subcutaneous formalin. Pain. 61:1995;11-16.
12. Deleo J.A., Coombs D.W., McCartlry L.E. Differential c-fos-like protein expression in mechanically versus chemically induced visceral nociception. Mol. Brain Res. 11:1991;167-170.
13. Dickenson A.H., Sullivan A.F. Electrophysiological studies on the effects of intrathecal morphine on nociceptive neurones in the rat dorsal horn. Pain. 24:1986;211-222.
14. Dickenson A.H., Sullivan A.F. Peripheral origins and central modulation of subcutaneous formalin induced activity of rat dorsal horn neurones. Neurosci. Lett. 83:1987;207-211.
15. Dickenson A.H., Sullivan A.F. Subcutaneous formalin-induced activity of dorsal horn neurons in the rat: differential response to an intrathecal opiate administered pre or post formalin. Pain. 30:1987;349-360.
16. Fitzgerald M. c-fos and the changing face of pain. Trends Neurosci. 13:1990;439-444.
17. Gogas K.R., Cho H.J., Botchkina G.I., Levine J.D., Basbaum A.I. Inhibition of noxious stimulus-evoked pain behaviors and neuronal fos-like immunoreactivity in the spinal cord of the rat by supraspinal morphine. Pain. 65:1996;9-15.
18. Gogas K.R., Presley R.W., Levine J.D., Basbaum A.I. The antinociceptive action of supraspinal opioids results from an increase in descending inhibitory control: correlation of nociceptive behavior and c-fos expression. Neuroscience. 42:1991;617-628.
19. Haley J.E., Sullivan A.F., Dickenson A.H. Evidence for spinal N-methyl-D-aspartate receptor involvement in prolonged chemical nociception in the rat. Brain Res. 518:1990;218-226.
20. Honoré P., Catheline G., Le Guen S., Besson J.-M. Chronic treatment with systemic morphine induced tolerance to the systemic and peripheral antinociceptive effects of morphine on both carrageenin induced mechanical hyperalgesia and spinal c-Fos expression in awake rats. Pain. 71:1997;99-108.
21. Honoré P., Chapman V., Buritova J., Besson J.-M. Concomitant administration of morphine and an N-methyl-D-aspartate receptor antagonist profoundly reduces inflammatory evoked spinal c-Fos expression. Anesthesiology. 85:1996;150-160.
22. Hsu S.-H., Raine L., Fanger H. Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase technique: a comparison between ABC and unlabeled antibody (PAP) procedures. J. Histochem. Cytochem. 29:1981;577-580.
23. Hunt S.P., Pini A., Evan G. Induction of c-fos-like protein in spinal cord neurons following sensory stimulation. Nature. 328:1987;632-634.
24. Jasmin L., Wang H., Tarczy-Hornoch K., Levine J.D., Basbaum A.I. Differential effects of morphine on noxious stimulus-evoked Fos-like immunoreactivity in subpopulations of spinoparabrachial neurons. J. Neurosci. 14:1994;7252-7260.
25. Lariviere W.R., Melzack R. The bee venom test: a new tonic-pain test. Pain. 66:1996;271-277.
26. Ma Q.-P., Woolf C.J. Basal and touch-evoked fos-like immunoreactivity during experimental inflammation in the rat. Pain. 67:1996;307-316.
27. Magnuson D.S.K., Dickenson A.H. Lamina-specific effects of morphine and naloxone in dorsal horn of rat spinal cord in vitro. J. Neurophysiol. 66:1991;1941-1950.
28. Menetrey D., Gannon A., Levine J.D., Basbaum A.I. Expression of c-fos protein in interneurons and projection neurons of the rat spinal cord in response to noxious somatic, articular and visceral stimulation. J. Comp. Neurol. 285:1989;177-195.
29. Molander C., Xu Q., Grant G. The cytoarchitectonic organization of the spinal cord in the rat: I. The lower thoracic and lumbosacral cord. J. Comp. Neurol. 230:1984;133-141.
30. Presley R.W., Menétrey D., Levine J.D., Basbaum A.I. Systemic morphine suppresses noxious stimulus-evoked Fos protein-like immunoreactivity in the rat spinal cord. J. Neurosci. 10:1990;323-335.
31. Puig S., Sorkin L.S. Formalin-evoked activity in identified primary afferent fibers: systemic lidocaine suppresses phase-2 activity. Pain. 64:1996;345-355.
32. Sastry B.R., Goh T. Actions of morphine and met-enkephalinamide in nociceptor driven neurons in substantia gelatinosa and deeper dorsal horn. Neuropharmacology. 22:1983;119-122.
33. Stein C. Peripheral mechanisms of opioid analgesia. Anesth. Analg. 76:1993;182-191.
34. Taylor B.K., Peterson M.A., Basbaum A.I. Persistent cardiovascular and behavioural nociceptive responses to subcutaneous formalin require peripheral nerve input. J. Neurosci. 15:1995;7575-7584.
35. Tjölsen A., Berge O.G., Hunskaar S., Rosland J.H., Hole K. The formalin test: an evaluation of the method. Pain. 51:1992;5-17.
36. Todd A.J., Spike R.C., Brodbelt A.R., Price R.F., Shehab S.A. Some inhibitory neurons in the spinal cord develop c-fos-immunoreactivity after noxious stimulation. Neuroscience. 63:1994;805-816.
37. Traub R.J., Stitt S., Gebhart G.F. Attenuation of c-Fos expression in the rat lumbosacral spinal cord by morphine or tramadol following noxious colorectal distention. Brain Res. 701:1995;175-182.
38. Williams S., Evan G.I., Hunt S.P. Changing patterns of c-fos induction in spinal neurons following thermal cutaneous stimulation in the rat. Neuroscience. 36:1990;73-81.
39. W.D. Willis, R.E. Coggeshall, Sensory Mechanisms of the Spinal Cord, 2nd edn., Plenum, New York, 1991, 153 pp.
40. Yamamoto T., Yaksh T.L. Comparison of the antinociceptive effects of pre- and posttreatment with intrathecal morphine and MK-801, an NMDA antagonist, on the formalin test in the rat. Anesthesiology. 77:1992;757-763.