Inhibition of carrageenan-induced spinal c-Fos activation by systemically administered c-fos antisense oligodeoxynucleotides may be facilitated by local opening of the blood-spinal cord barrier

Journal of Neuroscience Research

Volumn 47, Issue 6, 1997, Pages 582-589

  Gillardon, F ^a,c   Vogel, J ^a   Hein, S ^b   Zimmermann, M ^a   Uhlmann, E ^b  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b SANOFI   (France)

^c MAX PLANCK INSTITUTE FOR NEUROLOGICAL RESEARCH   (Germany)

Author keywords

c Fos; carrageenan; continuous infusion; dynorphin; miniosmotic pumps; partially phosphorothioated oligodeoxynucleotides; plasma extravasation; rat spinal cord

Indexed keywords

ANTISENSE OLIGODEOXYNUCLEOTIDE; CARRAGEENAN; DYNORPHIN; EVANS BLUE; NUCLEAR PROTEIN; OLIGODEOXYNUCLEOTIDE PHOSPHOROTHIOATE; PLASMA PROTEIN; TRANSCRIPTION FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GENE EXPRESSION REGULATION; INFLAMMATION; MALE; NERVE CELL PLASTICITY; NONHUMAN; ONCOGENE C FOS; ONCOGENE C JUN; PERMEABILITY BARRIER; PRIORITY JOURNAL; PROTO ONCOGENE; RAT; SPINAL CORD;

ANIMALS; BASE SEQUENCE; CAPILLARY PERMEABILITY; CARRAGEENAN; DYNORPHINS; GENE EXPRESSION REGULATION; GENES, FOS; INFLAMMATION; INFUSIONS, PARENTERAL; MICE; OLIGONUCLEOTIDES, ANTISENSE; PROTO-ONCOGENE PROTEINS C-FOS; RATS; SPINAL CORD; THIONUCLEOTIDES;

EID: 0030991778     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4547(19970315)47:6<582::AID-JNR3>3.0.CO;2-9     Document Type: Article

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