Superficial dorsal horn neurons identified by intracutaneous histamine: Chemonociceptive responses and modulation by morphine

Journal of Neurophysiology

Volumn 84, Issue 2, 2000, Pages 616-627

  Jinks, S L ^a   Carstens, E ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLYL ISOTHIOCYANATE; CAPSAICIN; HISTAMINE; IRRITANT AGENT; MORPHINE SULFATE; NALOXONE; NICOTINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CHEMOSENSITIVITY; CONTROLLED STUDY; EPIDURAL ANESTHESIA; EVOKED RESPONSE; FACILITATION; MALE; MECHANICAL STIMULATION; NEUROMODULATION; NOCICEPTION; NOCICEPTIVE STIMULATION; NONHUMAN; PRIORITY JOURNAL; PRURITUS; RAT; SIGNAL TRANSDUCTION; SINGLE UNIT ACTIVITY; SPINAL CORD DORSAL HORN; THERMAL STIMULATION;

EID: 0033837779     PISSN: 00223077     EISSN: None     Source Type: Journal    
DOI: 10.1152/jn.2000.84.2.616     Document Type: Article

References (98)

1. Intradermal leukotriene B4, but not prostaglandin E2, induces itch-associated responses in mice
2. Substance P induction of itch-associated response mediated by cutaneous NK1 tachykinin receptors in mice
3. Histamine-selective lamina I spinothalamic tract neurons
4. Itching after epidual and spinal opiates
5. Neurogenic hyperalgesia: The search for primary cutaneous afferent fibers that contribute to capsaicin-induced pain and hyperalgesia
6. Physiology and morphology of substantia gelatinosa neurons intracellularly stained with horseradish peroxidase
7. A peripheral 5-HT(ID)-like receptor involved in serotonergic induced hindlimb scratching in rats
8. Experiments relating to the itch sensation, its peripheral mechanism and central pathway
9. Quantitative sensory examination during epidural anaesthesia and analgesia in man: Effects of morphine
10. Observations on histamine-induced pruritis and pain
11. The price of intraspinal narcotic analgesia: Basic constraints
12. Nonrespiratory side effects of epidural morphine
13. Rostral spread of epidural morphine
14. Effects of menthol and cold on histamine-induced itch and skin reactions in man
15. Responses of rat spinal dorsal horn neurons to intracutaneous microinjection of histamine, capsaicin and other irritants
16. An electrophysiological study of neurones in the Substantia Gelatinosa Rolandi of the cat's spinal cord
17. Spinal neurons specifically excited by noxious or thermal stimuli: Marginal zone of the dorsal horn
18. Morphine enhances the activity of thermoreceptive cold-specific lamina I spinothalamic neurons in the cat
19. Effects of systemic morphine on lamina I spinothalamic tract neurons in the cat
20. Skin testing of the pruritogenic activity of histamine and cytokines (interleukin-2 and tumour necrosis factor-alpha) at the dermal-epidermal junction
21. Chemosensitivity and sensitization of nociceptive afferents that innervate the hairy skin of monkey
22. Electrophysiological studies of the effects of intrathecal morphine on nociceptive neurones in the rat dorsal horn
23. Suppression of transmission of nociceptive impulses by morphine: Selective effects of morphine administered in the region of the substantia gelatinosa
24. Evidence that disinhibition of brain stem neurones contributes to morphine analgesia
25. Comparison of continuous epidural infusion of fentanyl-bupivacaine and morphine-bupivacaine in management of postoperative pain
26. The stereospecific effect of naloxone on rat dorsal horn neurones: Inhibition in superficial laminae and excitation in deeper laminae
27. Automatic classification and analysis of microneurographic spike data using a PC/AT
28. The effects of thermal stimulation on clinical and experimental itch
29. Studies on the relief of pain by counterirritation
30. Inhibitory actions of delta 1-, delta 2-, and mu-opioid receptor agonists on excitatory transmission in lamina II neurons of adult rat spinal cord
31. Neural mechanisms involved in itch, itchy skin, and tickle sensations
32. Pathophysiology of itching
33. Spatial summation of chemical irritation and itch produced by topical application of capsaicin
34. The sensory response to capsaicin during repeated topical exposures: Differential effects on sensations of itching and pungency
35. Itch mediators
36. Pruritus after epidural morphine
37. Pain and allodynia, itch and alloknesis: An alternative hypothesis
38. Discharge patterns of human C-fibers induced by itching and burning stimuli
39. Quantitative evaluation of itch sensation
40. Opiate and HI antagonist effects on histamine induced pruritus and alloknesis
41. Enkephalins modulate excitatory synaptic transmission in the superficial dorsal horn by acting at mu-opioid receptor sites
42. Opiate analgesics inhibit substance P release from rat trigeminal nucleus
43. Spinal NMDA receptor involvement in the expansion of mechanosensitive receptive field area of dorsal horn neurons produced by intracutaneous microinjection of histamine
44. Skin cooling attenuates rat dorsal horn neuronal responses to intracutaneous histamine
45. Potential 'itch' neurons in superficial dorsal horn identified by intracutaneous histamine search stimulus: Modulation by noxious heat, algesic chemicals and intrathecal morphine
46. Opioids excite dopamine neurons by hyperpolarization of local interneurons
47. Effects of iontophoresed opioids on physiologically characterized laminae I and II dorsal horn neurons in the cat spinal cord
48. Experimental study of itch stimuli in animals
49. Actions of opioids on excitatory and inhibitory transmission in substantia gelatinosa of adult rat spinal cord
50. Responsiveness and functional attributes of electrically localized terminals of cutaneous C-fibers in vivo and in vitro
51. Scratching behavior induced by pruritogenic but not algesiogenic agents in mice
52. Opiate receptor binding in primate spinal cord: Distribution and changes after dorsal root section
53. Subpopulations of nocifensor neurons contributing to pain and allodynia, itch and alloknesis
54. Hypothesis for novel classes of chemoreceptors mediating chemogenic pain and itch
55. The role of spinothalamic tract neurons in itch and alloknesis
56. Morphological features of functionally defined neurons in the marginal zone and substantia gelatinosa of the spinal dorsal horn
57. Spinal laminae I-II neurons in rat recorded in vivo in whole cell, tight seal configuration: Properties and opioid responses
58. Neural mechanisms of itch sensation
59. Sensations and local inflammatory responses induced by application of carbachol, dopamine, 5-HT, histamine and mustard oil to the skin in humans
60. A reliable method for experimental itching by iontophoresis of histamine
61. Lamina-specific effects of morphine and naloxone in dorsal horn of rat spinal cord in vitro
62. Wide-dynamic-range dorsal horn neurons participate in the encoding process by which monkeys perceive the intensity of noxious heat stimuli
63. Neurophysiological characterization of the anterolateral spinal cord neurons contributing to pain perception in man
64. Itching for an explanation
65. Epidural and intrathecal opioids
66. Effects of ipsilateral and contralateral counterirritation on experimentally induced itch in human beings
67. Transmission of chronic nociception by spinal neurons expressing the substance P receptor
68. Sensations evoked by intraneural microstimulation of C nociceptor fibres in human skin nerves
69. Opioid actions on single nucleus raphe magnus neurons from rat and guinea-pig in vitro
70. Neurophysiological characterization of the anterolateral quadrant neurons subserving pain in M. mulatta
71. Physiology of itching
72. Actions of morphine and met-enkephalin-amide on nociceptor driven neurones in substantia gelatinosa and deeper dorsal horn
73. Specific C-receptors for itch in human skin
74. Chemical responsiveness of mechanosensitive and insensitive C-nociceptors in human skin
75. Pain and itch from intraneural microstimulation
76. Opioid-activated postsynaptic, inward rectifying potassium currents in whole cell recordings in substantia gelatinosa neurons
77. The neurohistology and neurophysiology of the itch sensation in man
78. Psychophysical studies of the itch sensation and itchy skin ('alloknesis') produced by intracutaneous injection of histamine
79. The magnitude and duration of itch produced by intracutaneous injections of histamine
80. Multiphasic effect of morphine on the release of substance P from rat trigeminal nucleus slices
81. Microinjection of morphine into the rat medullary dorsal horn produces a dose-dependent increase in facial scratching
82. Effect of central administration of opioids on facial scratching in monkeys
83. Intracisternal injection of opioids induces itch-associated response through μ-opioid receptors in mice
84. Itch evoked by electrical stimulation of the skin
85. Response to an itch-producing substance in cat. II. Cutaneous receptor populations with unmyelinated axons
86. A comparison of the effects of noxious and non-noxious counterstimuli on experimentally induced itch and pain
87. Response of cat ventrolateral spinal axons to an itch-producing stimulus (cowhage)
88. Pain and the Neurosurgeon: A Forty Year Experience
89. Actions of opioids on primate spinothalamic tract neurons
90. The Pain System
91. Characterization of a behavioral model for peripherally evoked itch suggests platelet-activating factor as a potent pruritogen
92. Lamina-specific alteration of C-fibre evoked activity by morphine in the dorsal horn of the rat spinal cord
93. Itch-associated response and antinociception induced by intracisternal endomorphins in mice
94. Histamine-caused itch induces Fos-like immunoreactivity in dorsal horn neurons: Effect of morphine pretreatment
95. Substantia gelatinosa neurones hyperpolarized in vitro by enkephalin
96. Effect of topically applied menthol on thermal, pain and itch sensations and biophysical properties of the skin