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Volumn 963, Issue , 2002, Pages 191-203

From castration-induced apoptosis of prostatic epithelium to the use of apoptotic genes in the treatment of prostate cancer

Author keywords

Apoptosis; Castration; Epithelium; Genes; Prostate cancer

Indexed keywords

ANDROGEN; ANDROGEN RECEPTOR; CASPASE INHIBITOR; PROTEIN BAX; PROTEIN BCL 2; REAGENT;

EID: 0036289530     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2002.tb04110.x     Document Type: Conference Paper
Times cited : (7)

References (83)
  • 1
    • 84928580276 scopus 로고
    • The effect of castration, of estrogens and androgen injection on serum phosphatase in metastatic carcinoma of the prostate
    • (1941) Cancer Res. , vol.1 , pp. 293-297
    • Huggins, C.1    Hodges, C.V.2
  • 2
    • 0032036584 scopus 로고    scopus 로고
    • Activation of the Src/p21ras/Erk pathway by progesterone receptor via cross-talk with estrogen receptor
    • (1998) Embo J. , vol.17 , pp. 2008-2018
    • Migliaccio, A.1
  • 3
    • 0034852802 scopus 로고    scopus 로고
    • Progesterone receptor contains a proline-rich motif that directly interacts with SH3 domains and activates c-Src family tyrosine kinases
    • (2001) Mol. Cell. , vol.8 , pp. 269-280
    • Boonyaratanakornkit, V.1
  • 4
    • 0028804247 scopus 로고
    • Mutant androgen receptors in prostatic tumors distinguish between amino-acid-sequence requirements for transactivation and ligand binding
    • (1995) Int. J. Cancer , vol.63 , pp. 544-550
    • Peterziel, H.1
  • 5
    • 0034675994 scopus 로고    scopus 로고
    • Steroid-induced androgen receptor-oestradiol receptor beta-Src complex triggers prostate cancer cell proliferation
    • (2000) Embo J. , vol.19 , pp. 5406-1547
    • Migliaccio, A.1
  • 6
    • 0035831020 scopus 로고    scopus 로고
    • Nongenotropic, sex-nonspecific signaling through the estrogen or androgen receptors: Dissociation from transcriptional activity
    • (2001) Cell , vol.104 , pp. 719-730
    • Kousteni, S.1
  • 7
    • 0025298231 scopus 로고
    • Programmed cell death during regression of PC-82 human prostate cancer following androgen ablation
    • (1990) Cancer Res. , vol.50 , pp. 3748-3753
    • Kyprianou, N.1
  • 9
    • 0033934609 scopus 로고    scopus 로고
    • Complete androgen blockade for prostate cancer: What went wrong?
    • (2000) J. Urol. , vol.164 , pp. 3-9
    • Laufer, M.1
  • 12
    • 0034610792 scopus 로고    scopus 로고
    • Caspases find a new place to hide [news]
    • (2000) Nature , vol.403 , pp. 29-30
    • Mehmet, H.1
  • 16
    • 0032892149 scopus 로고    scopus 로고
    • An elevated bax/bcl-2 ratio corresponds with the onset of prostate epithelial cell apoptosis
    • (1999) Cell Death Differ. , vol.6 , pp. 48-54
    • Perlman, H.1
  • 17
    • 0030584088 scopus 로고    scopus 로고
    • Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not Bcl-xl
    • (1996) Cell , vol.87 , pp. 619-628
    • Zha, J.1
  • 18
    • 0033582929 scopus 로고    scopus 로고
    • Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor
    • (1999) Cell , vol.96 , pp. 857-868
    • Brunet, A.1
  • 19
    • 0032515027 scopus 로고    scopus 로고
    • Regulation of cell death protease caspase-9 by phosphorylation
    • (1998) Science , vol.282 , pp. 1318-1321
    • Cardone, M.H.1
  • 21
    • 0033558215 scopus 로고    scopus 로고
    • The prosurvival Bcl-2 homolog Bfl-1/A1 is a direct transcriptional target of NF-kappaB that blocks TNFalpha-induced apoptosis
    • (1999) Genes Dev. , vol.13 , pp. 382-387
    • Zong, W.X.1
  • 22
    • 0032508414 scopus 로고    scopus 로고
    • NF-kappaB antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation
    • (1998) Science , vol.281 , pp. 1680-1683
    • Wang, C.Y.1
  • 24
    • 0033535350 scopus 로고    scopus 로고
    • Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis
    • (1999) J. Cell Biol. , vol.144 , pp. 891-901
    • Desagher, S.1
  • 25
    • 0033981577 scopus 로고    scopus 로고
    • Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane
    • (2000) Mol. Cell Biol. , vol.20 , pp. 929-935
    • Eskes, R.1
  • 26
    • 0033535347 scopus 로고    scopus 로고
    • Cell damage-induced conformational changes of the pro-apoptotic protein Bak in vivo precede the onset of apoptosis
    • (1999) J. Cell Biol. , vol.144 , pp. 903-014
    • Griffiths, G.J.1
  • 27
    • 0029101644 scopus 로고
    • Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death
    • (1995) J. Exp. Med. , vol.182 , pp. 367-377
    • Zamzami, N.1
  • 28
    • 0030581151 scopus 로고    scopus 로고
    • Induction of apoptotic program in cell-free extracts: Requirement for dATP and cytochrome c
    • (1996) Cell , vol.86 , pp. 147-157
    • Liu, X.1
  • 29
    • 0033521741 scopus 로고    scopus 로고
    • Molecular characterization of mitochondrial apoptosis-inducing factor
    • (1999) Nature , vol.397 , pp. 441-446
    • Susin, S.1
  • 30
    • 0034616945 scopus 로고    scopus 로고
    • Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition
    • (2000) Cell , vol.102 , pp. 33-42
    • Du, C.1
  • 31
    • 0035811496 scopus 로고    scopus 로고
    • Endonuclease G is an apoptotic DNase when released from mitochondria
    • (2001) Nature , vol.412 , pp. 95-99
    • Li, L.Y.1
  • 32
    • 0030715323 scopus 로고    scopus 로고
    • Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
    • (1997) Cell , vol.91 , pp. 479-489
    • Li, P.1
  • 33
    • 0034730153 scopus 로고    scopus 로고
    • Androgen-induced proliferative quiescence in prostate cancer cells: The role of AS3 as its mediator
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 10185-11090
    • Geck, P.1
  • 34
    • 0028944970 scopus 로고
    • Regulation of proliferation and production of prostate specific antigen in androgen-sensitive prostate cancer cells LNCaP, by dihydrotestosterone
    • (1995) Endocrinology , vol.136 , pp. 796-803
    • Lee, C.1
  • 35
    • 0024402439 scopus 로고
    • Negative controls of cell proliferation: Human prostate cancers and androgens
    • (1989) Cancer Res. , vol.49 , pp. 3474-3481
    • Sonnenschein, C.1
  • 37
    • 0021718260 scopus 로고
    • Successive waves of apoptosis in the rat prostate after repeated withdrawal of testosterone stimulation
    • (1984) Pathology , vol.16 , pp. 406-410
    • Sandford, N.L.1
  • 38
    • 0021796163 scopus 로고
    • Cellular response to androgen depletion and repletion in the rat ventral prostate: Autoradiography and morphometric analysis
    • (1985) Prostate , vol.7 , pp. 41-51
    • English, H.F.1
  • 42
    • 0023805088 scopus 로고
    • Cascade induction of c-fos, c-myc, and heat shock 70K transcripts during regression of the ventral prostate gland
    • (1988) Mol. Endocrinol. , vol.2 , pp. 650-657
    • Buttyan, R.1
  • 43
    • 0029884448 scopus 로고    scopus 로고
    • Down regulation of Bcl-2 is the first step on Fas-mediated apoptosis of male reproductive tract
    • (1996) Oncogene , vol.13 , pp. 31-37
    • Suzuki, A.1
  • 44
    • 0025999560 scopus 로고
    • Isolation and characterization of transcripts induced by androgen withdrawal and apoptotic cell death in the rat ventral prostate
    • (1991) Mol. Endocrinol. , vol.5 , pp. 1381-1388
    • Briehl, M.M.1    Miesfeld, R.L.2
  • 45
    • 0023645561 scopus 로고
    • Identification of glutathione S-transferase Yb1 mRNA as the androgen-repressed mRNA by cDNA cloning and sequence analysis
    • (1987) J. Biol. Chem. , vol.262 , pp. 11901-11193
    • Chang, C.S.1
  • 46
    • 0031734084 scopus 로고    scopus 로고
    • Antisense TR3 orphan receptor can increase prostate cancer cell viability with etoposide treatment
    • (1998) Endocrinology , vol.139 , pp. 2329-2334
    • Uemura, H.1    Chang, C.2
  • 47
    • 0029061350 scopus 로고
    • Prevention of cell death induced by tumor necrosis factor alpha in LNCaP cells by overexpression of sulfated glycoprotein-2 (clusterin)
    • (1995) Cancer Res. , vol.55 , pp. 2431-2437
    • Sensibar, J.A.1
  • 48
    • 0029875392 scopus 로고    scopus 로고
    • Changes in gene expression of growth factors and their receptors during castration-induced involution and androgen-induced regrowth of rat prostates
    • (1996) Prostate , vol.28 , pp. 139-152
    • Nishi, N.1
  • 49
    • 0027093255 scopus 로고
    • Expression of the protooncogene bcl-2 in the prostate and its association with emergence of androgen-independent prostate cancer
    • (1992) Cancer Res. , vol.52 , pp. 6940-6944
    • McDonnell, T.J.1
  • 50
    • 0027773015 scopus 로고
    • Detection of the apoptosis suppressing oncoprotein bcl-2 in hormone refractory human prostate cancers
    • (1993) Am. J. Pathol. , vol.143 , pp. 390-400
    • Colombel, M.1
  • 51
    • 0035866339 scopus 로고    scopus 로고
    • L underlies the molecular basis for resistance to staurosporine-induced apoptosis on PC-3 cells
    • (2001) Can. Res. , vol.61 , pp. 1699-1706
    • Li, X.-Y.1
  • 53
    • 0033561557 scopus 로고    scopus 로고
    • Calreticulin expression is associated with androgen regulation of the sensitivity to calcium ionophore-induced apoptosis in LNCaP prostate cancer cells
    • (1999) Cancer Res. , vol.59 , pp. 1896-1902
    • Zhu, N.1    Wang, Z.2
  • 54
    • 0026005818 scopus 로고
    • Programmed death of nonproliferating androgen-independent prostatic cancer cells
    • (1991) Cancer Res. , vol.51 , pp. 4693-4700
    • Martikainen, P.1
  • 55
    • 0028143317 scopus 로고
    • The role of calcium, pH, and cell proliferation in the programmed (apoptotic) death of androgen-independent prostatic cancer cells induced by thapsigargin
    • (1994) Cancer Res. , vol.54 , pp. 6167-6175
    • Furuya, Y.1
  • 57
    • 0031851943 scopus 로고    scopus 로고
    • Rapid reduction in blood flow to the rat ventral prostate gland after castration: Preliminary evidence that androgens influence prostate size by regulating blood flow to the prostate gland and prostatic endothelial cell survival
    • (1998) Prostate , vol.36 , pp. 201-206
    • Shabsigh, A.1
  • 59
    • 0035034989 scopus 로고    scopus 로고
    • Biomarker analysis demonstrates a hypoxic environment in the castrated rat ventral prostate gland
    • (2001) J. Cell Biochem. , vol.81 , pp. 437-444
    • Shabsigh, A.1
  • 60
    • 0034612768 scopus 로고    scopus 로고
    • Characterization of a zinc-finger protein and its association with apoptosis in prostate cancer cells
    • (2000) J. Natl. Cancer Inst. , vol.92 , pp. 1414-1421
    • Chang, G.T.1
  • 61
    • 0033119571 scopus 로고    scopus 로고
    • Antiapoptotic signaling in LNCaP prostate cancer cells: A survival signaling pathway independent of phosphatidylinositol 3′-kinase and Akt/protein kinase B
    • (1999) Cancer Res. , vol.59 , pp. 1449-1453
    • Carson, J.P.1
  • 62
    • 0035827510 scopus 로고    scopus 로고
    • Antagonism between PTEN/MMAC1/TEP-1 and androgen receptor in growth and apoptosis of prostatic cancer cells
    • (2001) J. Biol. Chem. , vol.276 , pp. 20444-20450
    • Li, P.1
  • 63
    • 0034671668 scopus 로고    scopus 로고
    • HER-2/neu promotes androgen-independent survival and growth of prostate cancer cells through the Akt pathway
    • (2000) Cancer Res. , vol.60 , pp. 6841-6845
    • Wen, Y.1
  • 64
    • 0035878820 scopus 로고    scopus 로고
    • Androgen blocks apoptosis of hormone-dependent prostate cancer cells
    • (2001) Cancer Res. , vol.61 , pp. 5611-5618
    • Kimura, K.1
  • 65
    • 0033899865 scopus 로고    scopus 로고
    • Differentially expressed genes in two LNCaP prostate cancer cell lines reflecting changes during prostate cancer progression
    • (2000) Lab. Invest. , vol.80 , pp. 1259-1268
    • Vaarala, M.H.1
  • 66
    • 0034326788 scopus 로고    scopus 로고
    • Dysregulated expression of androgen-responsive and nonresponsive genes in the androgen-independent prostate cancer xenograft model CWR22-R1
    • (2000) Cancer Res. , vol.60 , pp. 134-141
    • Amler, L.C.1
  • 67
  • 68
    • 0031963951 scopus 로고    scopus 로고
    • Caspase-7 is activated during lovastatin-induced apoptosis of the prostate cancer cell line LNCaP
    • (1998) Cancer Res. , vol.58 , pp. 76-83
    • Marcelli, M.1
  • 69
    • 0000835868 scopus 로고    scopus 로고
    • Signaling pathway activated during apoptosis of the prostate cancer cell line LNCaP: Overexpression of caspase-7 as a new gene therapy strategy for the treatment of prostate cancer
    • (1999) Cancer Res. , vol.59 , pp. 398-406
    • Marcelli, M.1
  • 70
    • 0033981234 scopus 로고    scopus 로고
    • Heterogeneous apoptotic responses of prostate cancer cell lines identify an association between sensitivity to staurosporine-induced apoptosis, expression of Bcl-2 family members, and caspase activation
    • (2000) Prostate , vol.42 , pp. 260-273
    • Marcelli, M.1
  • 71
    • 0027449187 scopus 로고
    • Induction of apoptosis in fibroblasts by IL-1β-converting enzyme, a mammalian homolog of the C elegans cell death gene ced-3
    • (1993) Cell , vol.75 , pp. 653-660
    • Miura, M.1
  • 72
    • 0030008812 scopus 로고    scopus 로고
    • ICE-LAP6, a novel member of the ICE/Ced-3 gene family, is activated by the cytotoxic T cell protease granzyme B
    • (1996) J. Biol. Chem. , vol.271 , pp. 16720-16724
    • Duan, H.1
  • 73
    • 0032562661 scopus 로고    scopus 로고
    • Generation of constitutively active recombinant caspases-3 and -6 by rearrangment of their subunit
    • (1998) J. Biol. Chem. , vol.273 , pp. 10107-10111
    • Srinivasula, S.1
  • 74
    • 0033927781 scopus 로고    scopus 로고
    • Induction of apoptosis in BPH stromal cells by adenoviral-mediated overexpression of caspase-7
    • (2000) J. Urol. , vol.164 , pp. 518-525
    • Marcelli, M.1
  • 75
    • 0035136282 scopus 로고    scopus 로고
    • Adenoviral-mediated Bax overexpression for the induction of therapeutic apoptosis in prostate cancer
    • (2001) Can. Res. , vol.61 , pp. 186-191
    • Li, X.-Y.1
  • 76
    • 0033967137 scopus 로고    scopus 로고
    • A binary adenoviral vector system for expressing high levels of the proapoptotic gene bax
    • (2000) Gene Ther. , vol.7 , pp. 75-79
    • Kagawa, S.1
  • 78
    • 0032528118 scopus 로고    scopus 로고
    • Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis
    • (1998) Embo J. , vol.17 , pp. 3878-3885
    • Gross, A.1
  • 79
    • 0034163805 scopus 로고    scopus 로고
    • Antitumor effect of adenovirus-mediated Bax gene transfer on p53- sensitive and p53-resistant cancer lines
    • (2000) Cancer Res. , vol.60 , pp. 1157-1161
    • Kagawa, S.1
  • 80
    • 0034520311 scopus 로고    scopus 로고
    • A small composite probasin promoter confers high levels of prostate-specific gene expression through regulation by androgens and glucocorticoids in vitro and in vivo
    • (2000) Endocrinology , vol.141 , pp. 4698-4710
    • Zhang, J.F.1
  • 81
    • 0035812239 scopus 로고    scopus 로고
    • Use of the probasin promoter ARR(2)PB to express bax in androgen receptor-positive prostate cancer cells
    • (2001) J. Natl. Cancer Inst. , vol.93 , pp. 1314-1324
    • Andriani, F.1
  • 82
    • 0033135221 scopus 로고    scopus 로고
    • In situ gene therapy for adenocarcinoma of the prostate: A phase I clinical trial
    • (1999) Hum. Gene Ther. , vol.10 , pp. 1239-1249
    • Herman, J.R.1
  • 83
    • 0034927685 scopus 로고    scopus 로고
    • Interleukin 2 gene therapy for prostate cancer: Phase I clinical trial and basic biology
    • (2001) Hum. Gene Ther. , vol.12 , pp. 883-892
    • Belldegrun, A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.