Perturbation of lipid metabolism by linoleic acid hydroperoxide in CaCo-2 cells

Biological Chemistry

Volumn 383, Issue 3-4, 2002, Pages 637-648

  Müller, Cordula ^a   Friedrichs, Bärbel ^a   Wingler, Kristin ^a   Brigelius Flohé, Regina ^a  

^a UNIVERSITY OF POTSDAM   (Germany)

Author keywords

Absorption of hydroperoxides; Gastrointestinal GPx; Intestinal triacylglycerol metabolism; Oxidative stress; Selenium

Indexed keywords

CARBON 14; CHOLESTEROL ESTER; CORIOLIC ACID; DIACYLGLYCEROL; FATTY ACID; GLUTATHIONE PEROXIDASE; HYDROPEROXIDE; LINOLEIC ACID; LIPOPROTEIN; PHOSPHOLIPID; SELENIUM;

ARTICLE; CELL STRAIN CACO 2; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOTOXICITY; DIETARY INTAKE; ESTERIFICATION; FATTY ACID OXIDATION; HUMAN; HUMAN CELL; INTESTINE EPITHELIUM; LIPID METABOLISM; MONOLAYER CULTURE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RADIOACTIVITY; SELENIUM DEFICIENCY;

BIOLOGICAL TRANSPORT; CACO-2 CELLS; CARBON RADIOISOTOPES; HUMANS; LINOLEIC ACIDS; LIPID METABOLISM; LIPID PEROXIDES; RADIOISOTOPE DILUTION TECHNIQUE;

EID: 0036244513     PISSN: 14316730     EISSN: None     Source Type: Journal    
DOI: 10.1515/BC.2002.066     Document Type: Article

References (84)

1. Dietary carcinogens and anticarcinogens
2. Toxicity of air-oxidized soybean oil
3. 14C-methyl linoleate hydroperoxide
4. Differences in the reducing power along rat GI tract: Lower antioxidant capacity of the colon
5. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of dye-binding
6. Tissue-specific functions of individual glutathione peroxidases
7. Selenium: An antioxidant?
8. Cellular glutathione peroxidase knockout mice express normal levels of selenium-dependent plasma and phospholipid hydroperoxide glutathione peroxidase in various tissues
9. Oxidized lipoproteins and atherosclerosis
10. Separation of lipid classes by high-performance liquid chromatography with the 'mass detector'
11. The expression of an intestinal form of glutathione peroxidase (GSHPx-GI) in rat intestinal epithelium
12. Expression, characterization, and tissue distribution of a new cellular selenium-dependent glutathione peroxidase, GSHPx-GI
13. Iron-ascorbate alters the efficiency of CaCo-2 cells to assemble and secrete lipoproteins
14. Epidermal growth factor regulates fatty acid uptake and metabolism in CaCo-2 cells
15. Synthesis and secretion of nascent lipoprotein particles
16. The effects of a dietary oxidized oil on lipid metabolism in rats
17. The effect of a moderately oxidized soybean oil on lipid peroxidation in rat low-density lipoproteins at low and high dietary vitamin E levels
18. Vitamin E status and tissue fatty acid composition in rats fed a moderately oxidized soybean oil at low or high vitamin E supply
19. Regulation of cholesterol esterification by micellar cholesterol in CaCo-2 cells
20. Assays of glutathione peroxidase
21. Oxygen-centered free radicals as mediators of inflammation
22. A simple method for the isolation and purification of total lipids from animal tissues
23. Evaluation of an isoluminol chemiluminescence assay for detection of hydroperoxides in human blood plasma
24. 13-HPODE and 13-HODE modulate cytokine-induced expression of endothelial cell adhesion molecules differently
25. Preparation and purification of lipid hydroperoxides from arachidonic and γ-linoleic acid
26. Heated fat, vitamin E and vascular eicosanoids
27. Lipid hydroperoxide generation, turnover, and effector action in biological systems
28. Intestinal absorption and lymphatic transport of methyl linoleate hydroperoxide and hydroxyoctadecadienoate in the rat
29. On the digestion and absorption of lipidperoxides
30. Role of reactive oxygen metabolites in inflammatory bowel disease
31. The importance of free radicals and catalytic metal ions in human diseases
32. Lipid peroxidation: Its mechanism, measurement and significance
33. Structure of low density lipoprotein (LDL) particles: Basis for understanding molecular changes in modified LDL
34. Lipid peroxides in the aging process
35. Chylomicron assembly and catabolism: Role of apolipoproteins and receptors
36. Biosynthesis of apolipoprotein B48-containing lipoproteins
37. Catabolic fate of dietary trilinoleoylglycerol hydroperoxides in rat gastrointestines
38. Lipid peroxides and nutrition
39. Developmental expression of extracellular glutathione peroxidase suggests antioxidant roles in deciduum, visceral yolk sac, and skin
40. Lipid oxidation products in food and atherogenesis
41. Trafficking of exogenous fatty acids within CaCo-2 cells
42. CaCo-2 cells as a model for intestinal lipoprotein synthesis and secretion
43. Assembly and secretion of chylomicrons by differentiated CaCo-2 cells. Nascent triacylglycerols and preformed phospholipids are preferentially used for lipoprotein assembly
44. Purification and characterization of thiol-reagent-sensitive glycerol-3-phosphate acyltransferase from the membrane fraction of an oleaginous fungus
45. Determination of phospholipid hydroperoxides using luminol chemiluminescence-high-performance liquid chromatography
46. Antioxidant defense in rat intestine and mesenteric lymph
47. 13-Hydroxy octadecadienoic acid (13-HODE) inhibits triacylglycerol-rich lipoprotein secretion by CaCo-2 cells
48. Oxidized LDL regulates macrophage gene expression through ligand activation of PPARγ
49. Consumption of red wine polyphenols reduces the susceptibility of low-density lipoproteins to oxidation in vivo
50. Very low density lipoproteins in intestinal lymph: Role in triglyceride and cholesterol transport during fat absorption
51. Very low density lipoproteins in intestinal lymph: Origin, composition, and role in lipid transport in the fasting state
52. Oxygen radicals: Mediators of gastrointestinal pathophysiology
53. Modified LDL - Trigger of atherosclerosis and inflammation in the arterial intima
54. Dietary oxidized fatty acids: An atherogenic risk?
55. Absorption by the rat of nonvolatile oxidation products of labeled randomized corn oil
56. Enterocyte-like differentiation and polarization of the human colon carcinoma cell line CaCo-2 in culture
57. Free radical biology: Xenobiotics, cancer and aging
58. Influence of eicosapentaenoic acid (20:5, n-3) on secretion of lipoproteins in CaCo-2 cells
59. 4C-hydroxy octadecadienoate in the rat
60. Wine, alcohol, platelets and the French paradox
61. Metabolism of 15-hydroxyeicosatetraenoic acid by CaCo-2 cells
62. Subcellular distribution and some properties of N-ethylmaleimide-sensitive and -insensitive forms of glycerol phosphate acyltransferase in rat adipocytes
63. Dithiocarbamates: Effects on lipid hydroperoxides and vascular inflammatory gene expression
64. Effect of dietary lipid peroxides on metabolism of serum chylomicrons in rats
65. Oxidized lipids in the diet are incorporated by the liver into very low density lipoprotein in rats
66. Oxidized lipids in the diet accelerate the development of fatty streaks in cholesterol-fed rabbits
67. Beyond cholesterol: Modifications of low-density lipoprotein that increases its atherogenicity
68. Activation of protein kinase C by oxidized diacylglycerols
69. Polarized secretion of newly synthesized lipoproteins by the CaCo-2 human intestinal cell line
70. Fatty acid esterification during differentiation of the human intestinal cell line CaCo-2
71. Fatty acid uptake by CaCo-2 human intestinal cells
72. Wine antioxidants: Effects in vitro and in vivo
73. Postprandial plasma lipid hydroperoxides: A possible link between diet and atherosclerosis
74. Role of reactive oxygen species in intestinal diseases
75. The enzymatic and non-enzymatic roles of protein-disulfide isomerase in apolipoprotein B secretion
76. Decreased erythrocyte glutathione peroxidase activity in neuronal lipofuscinosis (NCL)-corrected with selenium supplementation
77. Structural properties of the microsomal triglyceride transfer protein complex
78. Absence of microsomal triglyceride transfer protein in individuals with α-betalipoproteinemia
79. mRNA stability and selenocysteine insertion sequence efficiency rank gastrointestinal glutathione peroxidase high in the hierarchy of selenoproteins
80. Gastrointestinal glutathione peroxidase prevents transport of lipid hydroperoxides in CaCo-2 cells
81. Hypothesis: UK consumption of dietary lipid hydroperoxides - A possible contributory factor to atherosclerosis
82. Lesion of aortic intima caused by intravenous administration of linoleic acid hydroperoxide
83. Use of a new methylene blue derivative for determination of lipid peroxides in foods
84. 1,2-Diacylglycerol hydroperoxides induce the generation and release of superoxide anion from human polymorphonuclear leukocytes