Transfer of GRP94(Gp96)-Associated peptides onto endosomal MHC class I molecules

Traffic

Volumn 3, Issue 5, 2002, Pages 358-366

  Berwin, B ^a   Rosser, M F N ^a   Brinker, G ^a   Nicchitta, C V ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

CD1; Cross presentation; Dendritic cell; gp96; GRP94; Macrophage; MHC class I

Indexed keywords

CD1 ANTIGEN; CELL SURFACE RECEPTOR; CYTOPLASM PROTEIN; FC RECEPTOR; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MONOCLONAL ANTIBODY; PEPTIDE; RAB PROTEIN; TRANSFERRIN;

ANIMAL CELL; ANTIGEN PRESENTING CELL; ASSAY; CELLULAR IMMUNITY; CONTROLLED STUDY; ENDOCYTOSIS; ENDOPLASMIC RETICULUM; ENDOSOME; INTERNALIZATION; KINETICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVIEW; SYNTHESIS;

AMINO ACID SEQUENCE; ANIMALS; ENDOCYTOSIS; ENDOSOMES; HISTOCOMPATIBILITY ANTIGENS CLASS I; HSP70 HEAT-SHOCK PROTEINS; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; PEPTIDES;

EID: 0036237529     PISSN: 13989219     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-0854.2002.30505.x     Document Type: Review

References (47)

1. Heat shock proteins: The fountainhead of innate and adaptive immune responses
2. Immunotherapy of tumors with autologous tumor-derived heat shock protein preparation
3. Virally induced lytic cell death elicits the release of immunogenic GRP94/gp96
4. Necrotic but not apoptotic cell death releases heat shock proteins, which deliver a partial maturation signal to dendritic cells and activate the NF-kappa β pathway
5. Calreticulin displays in vivo peptide-binding activity and can elicit CTL responses against bound peptides
6. The heat shock protein gp96, a receptor-targeted cross-priming carrier and activator of dendritic cells
7. A mechanism for the specific immunogenicity of heat shock protein-chaperoned peptides
8. Influences of transporter associated with antigen processing (TAP) on the repertoire of peptides associated with the endoplasmic reticulum-resident stress protein gp96
9. The endoplasmic reticulum-resident stress protein gp96 binds peptides translocated by TAP
10. TAP-translocated peptides specifically bind proteins in the endoplasmic reticulum, including gp96, protein disulfide isomerase and calreticulin
11. Heat shock proteins: The 'Swiss Army Knife' vaccines against cancers and infectious agents
12. Biochemical, cell biological and immunological issues surrounding the endoplasmic reticulum chaperone GRP94/gp96
13. Proteolysis in MHC class II antigen presentation: Who's in charge?
14. Intracellular surveillance: Controlling the assembly of MHC class I-peptide complexes
15. Mechanisms of exogenous antigen presentation by MHC class I molecules in vitro and in vivo: Implications for generating CD8+ T cell responses to infectious agents, tumors, transplants, and vaccines
16. Cross-presentation of glycoprotein 96-associated antigens on major histocompatibility complex class I molecules requirese receptor-mediated endocytosis
17. Receptor mediated and fluid phase pathways for internalization of the ER Hsp90 chaperone GRP94 in murine macrophages
18. CD91: A receptor for heat shock protein gp96
19. CD91 is a common receptor for heat shock proteins gp96, hsp90, hsp70, and calreticulin
20. Cutting edge, receptor-mediated endocytosis of heat shock proteins by professional antigen-presenting cells
21. 2-macroglobulin, an independent ligand for the heat shock protein receptor CD91
22. 2-Macroglobulin, complement, and biologic defense: Antigens, growth factors, microbial proteases, and receptor ligation
23. Biogenesis of the sorting endosome: The role of Rab5
24. The receptor recycling pathway contains two distinct populations of early endosomes with different sorting functions
25. Distinct membrane domains on endosomes in the recycling pathway visualized by multicolor imaging of Rab4, Rab5, and Rab11
26. Membrane transport in the endocytic pathway
27. Transport of macrophage Fc receptors and Fc receptor-bound ligands to lysosomes
28. Colocalization of Fc gamma RI-targeted antigen with class I MHC: Implications for antigen processing
29. Fc receptor biology
30. Cutting edge: Tumor secreted heat shock-fusion protein elicits CD8 cells for rejection
31. Fcγ receptor-mediated induction of dendritic cell maturation and major histocompatibility complex class I-restricted antigen presentation after immune complex internalization
32. Structures and functions of multiligand lipoprotein receptors: Macrophage scavenger receptors and LDL receptor-related protein (LRP)
33. CD1 and lipid antigens: Intracellular pathways for antigen presentation
34. Antigen traffic pathways in dendritic cells
35. Class I MHC presentation of exogenous antigens
36. Exogenous peptides enter the endoplasmic reticulum of TAP-deficient cells and induce the maturation of nascent MHC class I molecules
37. Direct delivery of exogenous MHC class I molecule-binding oligopeptides to the endoplasmic reticulum of viable cells
38. Receptor-mediated uptake of antigen/heat shock protein complexes results in major histocompatibility complex class I antigen presentation via two distinct processing pathways
39. 2-macroglobulin and polypeptide hormones
40. Heat shock protein-peptide complexes, reconstituted in vitro, elicit peptide-specific cytotoxic T lymphocyte response and tumor immunity
41. Antigen loading of MHC class I molecules in the endocytic tract
42. Recycling MHC class I molecules and endosomal peptide loading
43. Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor
44. Purification and partial molecular characterization of GRP94, an ER resident chaperone
45. Differential microtubule requirements for transcytosis in MDCK cells
46. Localization, quantitation, and in situ detection of specific peptide-MHC class I complexes using a monoclonal antibody
47. Methods in Enzymology