Colocalization of FcγRI-targeted antigen with class I MHC: Implications for antigen processing

Journal of Immunology

Volumn 166, Issue 4, 2001, Pages 2469-2478

  Guyre, C A ^a   Barreda, M E ^a   Swink, S L ^a   Fanger, M W ^a  

^a DARTMOUTH MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FC RECEPTOR; GREEN FLUORESCENT PROTEIN; HYBRID PROTEIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MONOCLONAL ANTIBODY;

ANTIGEN PRESENTATION; ANTIGEN PRESENTING CELL; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; ENDOSOME; FLOW CYTOMETRY; HUMAN; HUMAN CELL; INTERNALIZATION; MAJOR HISTOCOMPATIBILITY COMPLEX; PRIORITY JOURNAL;

EID: 0035865402     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.166.4.2469     Document Type: Article

References (28)

1. Antigen targeting
2. Increased potency of Fc-receptor-targeted antigens
3. Enhanced antigen presentation using human Fcγ receptor (monocyte/macrophage)-specific immunogens
4. FcγRII on human B cells can mediate enhanced antigen presentation
5. Antigen targeting to myeloid-specific human FcγRI/CD64 triggers enhanced antibody responses in transgenic mice
6. FcγRI-targeted fusion proteins result in efficient presentation by human monocytes of antigenic and antagonist T cell epitopes
7. Characterization of expression, cytokine regulation, and effector function of the high affinity IgG receptor FcγRI (CD64) expressed on human blood dendritic cells
8. Fcγ receptor-mediated induction of dendritic cell maturation and major histocompatibility complex class I-restricted antigen presentation after immune complex internalization
9. Class I-restricted presentation of exogenous antigen acquired by Fcγ receptor-mediated endocytosis is regulated in dendritic cells
10. Antigen targeted to FcγRI is presented in association with MHC class I
11. A new foreign policy: MHC class I molecules monitor the outside world
12. Recycling MHC class I molecules and endosomal peptide loading
13. Trafficking of spontaneously endocytosed MHC proteins
14. Functional comparison of the inductions of NADPH oxidase activity and FcγRI in IFN γ-treated U937 cells
15. Production of monoclonal antibodies to group A erythrocytes, HLA and other human cell surface antigens: New tools for genetic analysis
16. Hybrid cell line from a cloned immunoglobulin-producing mouse myeloma and a nonproducing mouse lymphoma
17. Individual and combined tumoricidal effects of dexamethasone and interferons on human leukocyte cell lines
18. Gamma-interferon and expression of MHC genes regulate peptide hydrolysis by proteasomes
19. The diversity of Rab proteins in vesicle transport
20. Endocytosis and molecular sorting
21. Lysosome-endosome fusion and lysosome biogenesis
22. Lysosomal membrane glycoproteins: Structure, biosynthesis, and intracellular trafficking
23. Green fluorescent protein as a noninvasive intracellular pH indicator
24. The (α2→8)-linked polysialic acid capsule of group B Neisseria meningitidis modifies multiple steps during interaction with human macrophages
25. Intracellular trafficking and killing of Streptococcus pneumoniae by human alveolar macrophages are influenced by opsonins
26. 2-macroglobulin and transferrin: A kinetic study using a monoclonal antibody against a lysosomal membrane glycoprotein (LAMP-1)
27. Selective transport of internalized antigens to the cytosol for MHC class I presentation in dendritic cells
28. The FcγRIa (CD64) ligand binding chain triggers major histocompatibility complex class II antigen presentation independently of its associated FcRγ-chain