Biochemical, cell biological and immunological issues surrounding the endoplasmic reticulum chaperone GRP94/gp96

Current Opinion in Immunology

Volumn 10, Issue 1, 1998, Pages 103-109

  Nicchitta, Christopher V ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHAPERONE; GLUCOSE REGULATED PROTEIN; PEPTIDE; TUMOR ANTIGEN;

ANTIGEN PRESENTATION; ANTIGEN PRESENTING CELL; BIOCHEMISTRY; CANCER IMMUNOTHERAPY; CELLULAR DISTRIBUTION; CYTOLOGY; ENDOPLASMIC RETICULUM; HUMAN; IMMUNE RESPONSE; NONHUMAN; PHYLOGENY; PROTEIN BINDING; PROTEIN STRUCTURE; REVIEW;

EID: 0032007324     PISSN: 09527915     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0952-7915(98)80039-3     Document Type: Article

References (51)

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5. + response against the parent tumor, as well as metastatic lesions. Tumor-derived heat shock protein - peptide complexes are shown to be effective immunother-apeutic agents against spontaneous, chemically induced and UV light-induced cancers. This consistutes the first demonstration that heat shock proteins vaccines are effective in models of pre-existing cancer.
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