P2 receptor modulation and cytotoxic function in cultured CNS neurons

Neuropharmacology

Volumn 42, Issue 4, 2002, Pages 489-501

  Amadio, S ^a   D'Ambrosi, N ^a,c   Cavaliere, F ^a,c   Murra, B ^a   Sancesario, G ^c   Bernardi, G ^a,c   Burnstock, G ^d   Volonte C ^a,b  

^a IRCCS FONDAZIONE SANTA LUCIA   (Italy)

^b CNR   (Italy)

^c UNIVERSITY OF ROME TOR VERGATA   (Italy)

^d ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

Author keywords

Apoptosis; Extracellular ATP; Granule neurons; Hippocampal organotypic cultures; Necrosis; P2 receptors

Indexed keywords

1 [N,O BIS(5 ISOQUINOLINESULFONYL) N METHYLTYROSYL] 4 PHENYLPIPERAZINE; 2 AMINO 5 PHOSPHONOVALERIC ACID; 2 CHLOROADENOSINE 5' TRIPHOSPHATE; 2 METHYLTHIOADENOSINE TRIPHOSPHATE; 3 AMINO 1 HYDROXY 2 PYRROLIDINONE; 3' O (4 BENZOYLBENZOYL)ADENOSINE TRIPHOSPHATE; 4,4' DIISOTHIOCYANATOSTILBENE 2,2' DISULFONIC ACID; ADENOSINE; ADENOSINE 5' O (3 THIOTRIPHOSPHATE); ADENOSINE DERIVATIVE; ADENOSINE DIPHOSPHATE; ADENOSINE PHOSPHATE; ADENOSINE TETRAPHOSPHATE; ADENOSINE TRIPHOSPHATE; ADENOSINE TRIPHOSPHATE 2',3' DIALDEHYDE; ADENYLYLIMIDODIPHOSPHATE; ALDEHYDE DERIVATIVE; ANTHRAQUINONE DERIVATIVE; BETA,GAMMA METHYLENEADENOSINE TRIPHOSPHATE; CAFFEINE; CALMIDAZOLIUM; DIZOCILPINE; LACTATE DEHYDROGENASE; MESSENGER RNA; PURINE P2X RECEPTOR; PURINE P2Y RECEPTOR; PYRIDOXAL 5 PHOSPHATE; PYRIDOXAL PHOSPHATE 6 AZOPHENYL 2',4' DISULFONIC ACID; RECEPTOR PROTEIN; RECEPTOR PROTEIN P2; RECEPTOR SUBTYPE; SURAMIN; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN NERVE CELL; CELL DEATH; CELL DIFFERENTIATION; CELL MATURATION; CELL NUCLEUS; CELL SWELLING; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; CYTOTOXICITY; ENZYME RELEASE; GRANULE CELL; HIPPOCAMPUS; NERVE DEGENERATION; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STRIATE CORTEX; WESTERN BLOTTING;

ADENOSINE TRIPHOSPHATE; ANIMALS; CELLS, CULTURED; CENTRAL NERVOUS SYSTEM; CEREBELLUM; DOSE-RESPONSE RELATIONSHIP, DRUG; HIPPOCAMPUS; INTRACELLULAR FLUID; MEMBRANE POTENTIALS; MICROELECTRODES; NEURONS; PATCH-CLAMP TECHNIQUES; RATS; RATS, WISTAR; RECEPTORS, PURINERGIC P2;

EID: 0036223122     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(01)00197-6     Document Type: Article

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