Characterization of the signalling pathways involved in ATP and basic fibroblast growth factor-induced astrogliosis

British Journal of Pharmacology

Volumn 121, Issue 8, 1997, Pages 1692-1699

  Bolego, Chiara ^a   Ceruti, Stefania ^a   Brambilla, Roberta ^a   Puglisi, Lina ^a   Cattabeni, Flaminio ^a   Burnstock, Geoffrey ^b   Abbracchio, Maria P ^a  

^a UNIVERSITY OF MILAN   (Italy)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Astrocytic differentiation; Basic fibroblast growth factor (bFGF) receptors; P2 receptors; Primary response genes; Rat brain astrocytes: glial fibrillary acidic protein (GFAP)

Indexed keywords

1 (5 ISOQUINOLINESULFONYL) 2 METHYLPIPERAZINE; ADENOSINE TRIPHOSPHATE; ADENYLATE CYCLASE; ALPHA,BETA METHYLENEADENOSINE TRIPHOSPHATE; ARACHIDONIC ACID; BASIC FIBROBLAST GROWTH FACTOR; BETA,GAMMA METHYLENEADENOSINE TRIPHOSPHATE; CYCLIC AMP; DEXAMETHASONE; GENISTEIN; MEPACRINE; NEOMYCIN; PERTUSSIS TOXIN; PHOSPHOLIPASE A2; PHOSPHOLIPASE C; PROTEIN TYROSINE KINASE; PURINE DERIVATIVE; PURINE P2Y RECEPTOR; SURAMIN; URIDINE TRIPHOSPHATE;

ANIMAL CELL; ARTICLE; ASTROCYTE; ASTROCYTOSIS; CELL CULTURE; CELL DIFFERENTIATION; CELL STRUCTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVATION; NEUROLOGIC DISEASE; NONHUMAN; ONCOGENE C FOS; ONCOGENE C JUN; PRIORITY JOURNAL; PROVOCATION TEST; RAT; SIGNAL TRANSDUCTION;

ADENOSINE TRIPHOSPHATE; ANIMALS; ARACHIDONIC ACID; ASTROCYTES; CELL DIFFERENTIATION; CELLS, CULTURED; FIBROBLAST GROWTH FACTOR 2; PROTEIN KINASE C; RATS; RECEPTORS, PURINERGIC P2;

EID: 0030841180     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0701294     Document Type: Article

References (45)

1. ABBRACCHIO, M.P. (1997). ATP in brain function. In Purinergic Approaches in Experimental Therapeutics. ed. Jacobson K. & Jarvis, M.F. in press, New York, U.S.A.: Wiley & Sons, Inc.
2. ABBRACCHIO, M.P. & BURNSTOCK, G. (1994). Purinoceptors: are there families of P2X and P2Y purinoceptors? Pharmacol. Ther., 64, 445-475.
3. ABBRACCHIO, M.P., CERUTI, S., BOLEGO, C., PUGLISI, L., BURNSTOCK, G. & CATTABENI, F. (1996). Trophic roles of P2 purinoceptors in central nervous system astroglial cells. In Proceedings of the Ciba Foundation Symposium 198 on: P2 Purinoceptors: Localization, Function and Transduction Mechanisms. pp. 141-147. Chichester: Wiley.
4. ABBRACCHIO, M.P., CERUTI, S., BURNSTOCK, G. & CATTABENI, F. (1995a). Purinoceptors on glial cells of the central nervous system: functional and pathological implications. In Adenosine and Adenine Nucleotides: from Molecular Biology to Integrative Physiology. ed. Belardinelli, L. & Pelleg, A. pp. 271-280. Norwell, MA: Kluwer Acad. Publ.
5. ABBRACCHIO, M.P., CERUTI, S., LANGFELDER, R., CATTABENI, F., SAFFREY, M.J. & BURNSTOCK, G. (1995b). Effects of ATP analogues and basic fibroblast growth factor on astroglial cell differentiation in primary cultures of rat striatum. Int. J. Devl. Neurosci., 13, 685-693.
6. ABBRACCHIO, M.P., DI LUCA, M., DI GIULIO, A.M., CATTABENI, F., TENCONI, B. & GORIO, A. (1989). Denervation and hyperinnervation in the nervous system of diabetic animals: III. Functional alterations of G proteins in diabetic encephalopathy. J. Neurosci. Res., 24, 517-523.
7. ABBRACCHIO, M.P., SAFFREY, M.J., HOPKER, V. & BURNSTOCK, G. (1994). Modulation of astroglial cell proliferation by analogues of adenosine and ATP in primary cultures of rat striatum. Neuroscience, 59, 67-76.
8. ANGEL, P., ALLEGRETTO, E.A., OKINO, S.T., HATTORI, K., BOYLE, W.J., HUNTER, T. & KARIN, M. (1988). Oncogene jun encodes a sequence-specific transactivator similar to AP-1. Nature, 332, 166-171.
9. ARENANDER, A.T., LIM, R.W., VARNUM, B.C., COLE, R., DE VELLIS, J. & HERSCHMAN, H.R. (1989). TIS gene expression in cultured rat astrocytes: multiple pathways of induction by mitogens. J. Neurosci. Res., 23, 257-265.
10. AVRUCH, J., ZHANG, X.-F. & KYRIAKIS, J.M. (1994). Raf meets Ras: completing the framework of a signal transduction pathway. Trends Biochem. Sci., 19, 279-283.
11. 2 via GTP-binding proteins: arachidonic acid and its metabolites as second messengers. Trends Neurosci., 11, 117-123.
12. BARRES, B.A. (1991). New roles for glia. J. Neurosci. Res., 11, 3685-3694.
13. 2Y purinoceptors. Mol. Pharmacol., 35, 526-532.
14. BOYER, J.L., LAZAROWSKI, E.R., CHEN, X.-H. & HARDEN, T.K. (1993). Identification of a P2y-purinergic receptor that inhibits adenylyl cyclase. J. Pharmacol. Exp. Ther., 267, 1140-1146.
15. 2Y-purinergic receptor. J. Neurochem., 55, 1569-1575.
16. BURNSTOCK, G. (1996). P2 purinoceptors: historical perspective and classification. In Proceedings of the Ciba Foundation Symposium 198 on: P2 Purinoceptors: Localization, Function and Transduction Mechanisms. pp. 1-33. Chichester: Wiley.
17. BURNSTOCK, G. & KING, B.F. (1996). Numbering of cloned P2 purinoceptors. Drug Dev. Res., 38, 67-71.
18. 2+ responses evoked by ATP and other nucleotides in mammalian brain astroyctes. Br. J. Pharmacol., 121, 1700-1706.
19. CHAREST, R., BLACKMORE, P.F. & EXTON, J.H. (1985). Characterization of responses of isolated rat epatocytes to ATP and ADP. J. Biol. Chem., 260, 15789-15794.
20. CLAPHAM, D.E. & NEER, E.J. (1993). New roles for G protein βγ dimers in transmembrane signalling. Nature, 365, 403-406.
21. DAVIS, R.J. (1993). The mitogen-activated protein kinase signal transduction pathway. J. Biol. Chem., 268, 14553-14556.
22. EDDLESTON, M. & MUCKE, L. (1993). Molecular profile of reactive astrocytes-implication for their role in neurologic diseases. Neuroscience, 54, 15-36.
23. 2-purinergic receptors. Proc. Natl. Acad. Sci. U.S.A., 84, 5630-5634.
24. GILLE, H., SHARROCKS, A.D. & SHAW, P.E. (1992). Phosphorylation of transcription factor P62TCF by MAP kinase stimulates ternary complex formation at c-fos promotor. Nature, 358, 414-417.
25. HATTEN, M.E., LIEM, R.K.H., SHELANSKI, M.L. & MASON, C.A. (1991). Astroglia in CNS injury. Glia, 4, 233-243.
26. LANGE-CARTER, C.A., PLEIMAN, C.M., GARDNER, A.M., BLUMER, K.J. & JOHNSON G.L. (1993). A divergence in the MAK kinase regulatory network defined by MEK kinase and Raf. Science, 260, 315-319.
27. MORGAN, J.I. & CURRAN, L. (1991). Stimulus transcription coupling in the central nervous system: involvement of the inducible protooncogenes fos and jun. Ann. Rev. Neurosci., 14, 421-451.
28. MURPHY, S., PEARCE, B., JEREMY, J. & DANDONA, P. (1988). Astrocytes as eicosanoids-producing cells. Glia, 1, 241-245.
29. NEARY, J.T. & ZHU, Q. (1994). Signaling by ATP receptors in astrocytes. NeuroReport, 5, 1617-1620.
30. NEARY, J.T., ZHU, Q., BRUCE, J.H., MOORE, A.N. & DASH, P.K. (1994). Synergistic activation of AP-1 complexes by ATP and bFGF in astrocytes. Soc. Neurosci. Abstr., 29, 1501.
31. NEARY, J.T., RATHBONE, M.P., CATTABENI, F., ABBRACCHIO, M.P. & BURNSTOCK, G. (1996). Trophic actions of extracellular nucleotides and nucleosides on glial and neuronal cells. Trends Neurosci., 19, 13-18.
32. PETRONI, A., SALAMI, M., BLASEVICH, M., PAPINI, N. & GALLI, C. (1994). Inhibition by n-3 fatty acids of arachidonic acid metabolism in a primary culture of astroglial cells. Neurochem. Res., 19, 1187-1193.
33. PIROTTON, S., RASPE, E., DEMOLLE, D., ERNEUX, C. & BOEYNAEMS, J.M. (1987). Involvement of inositol 1,4,5-trisphosphate and calcium in the action of adenine nucleotides on aortic endothelial cells. J. Biol. Chem., 262, 17461-17466.
34. PULVERER, B.J., KYRIAKID, J.M., AVRUCH, J., NIKOLAKAKI, E. & WOODGETT, J.R. (1991). Phosphorylation of c-Jun mediated by MAP kinases. Nature, 353, 670-674.
35. RAKIC, P. (1991). Glial cells in development. Ann. New York Acad. Sci., 633, 96-99.
36. SALOMON, Y.C., LONDOS, C. & RODBELL, M. (1974). A highly-sensitive adenylate cyclase assay. Anal. Biochem., 58, 541-548.
37. 2+ via the phospholipase Cβ/IP3 pathway in astrocytes from the dorsal spinal cord. J. Neurosci., 15, 2961-2971.
38. SAMBUCETTI, L.C. & CURRAN, T. (1986). The fos protein complex is associated with DNA in isolated nuclei and binds to DNA cellulose. Science, 234, 1417-1419.
39. STELLA, N., TENCE', M., GLOWINSKI, J. & PREMONT, J. (1994). Glutamate-evoked release of arachidonic acid from mouse brain astrocytes. J. Neurosci., 14, 568-575.
40. 2X receptors bring new structure to ligand-gated ion channels. Trends Neurosci., 18, 224-229.
41. TANAKA, C. & NISHIZUKA, Y. (1994). The protein kinase C family for neuronal signalling. Annu. Rev. Neurosci., 17, 551-567.
42. VOOGD, T.E., VANSTERKENBURG, E.L.M., WILTING, J. & JANSSEN, L.H.M. (1993). Recent research on the biological activity of suramin. Pharmacol. Rev., 45, 177-203.
43. WEINSTEIN, D.E., SHELANSKI, M.L. & LIEM, R. (1991). Suppression by antisense mRNA demonstrates a requirement for the glial fibrillary acidic protein in the formation of stable astrocytic processes in response to neurons. J. Cell. Biol., 112, 1205-1213.
44. WILLIAMS, M. & JACOBSON, K.A. (1995). P2-purinoceptors: advances and therapeutic opportunities. Exp. Opin. Invest. Drugs, 4, 925-934.
45. WINDSCHEIF, U., PFAFF, G., ZIGANSHIN, A.U., HOYLE, C.H., BAUMERT, H.G., MUTSCHLER, E., BURNSTOCK, G. & LAMBRECHT, G. (1995). Inhibitory action of PPADS on relaxant responses to adenine nucleotides or electrical field stimulation in guinea pig taenia coli and rat duodenum. Br. J. Pharmacol., 115, 1509-1517.