Structural analyses reveal two distinct families of nucleoside phosphorylases

Biochemical Journal

Volumn 361, Issue 1, 2002, Pages 1-25

  Pugmire, Matthew J ^a   Ealick, Steven E ^a  

^a Department of Molecular Biology and Genetics   (United States)

Author keywords

Active site; Inhibitors; Purine nucleoside phosphorylase; Pyrimidine nucleoside phosphorylase; Quaternary structure

Indexed keywords

AMINO ACIDS; CATALYSIS; CONFORMATIONS; ENZYMES;

SALVAGE PATHWAYS;

BIOCHEMISTRY;

5' METHYLTHIOADENOSINE; NUCLEOSIDE PHOSPHORYLASE; PROTEIN SUBUNIT; PURINE NUCLEOSIDE; PYRIMIDINE NUCLEOSIDE; S ADENOSYLHOMOCYSTEINE; THYMIDINE; URIDINE;

AMINO ACID SEQUENCE; BIOSYNTHESIS; CATALYSIS; DEPHOSPHORYLATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME SPECIFICITY; ENZYME SUBSTRATE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN FOLDING; PROTEIN MOTIF; PROTEIN QUATERNARY STRUCTURE; REVIEW; SEQUENCE HOMOLOGY; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; ENZYME INHIBITORS; EVOLUTION, MOLECULAR; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PENTOSYLTRANSFERASES; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN STRUCTURE, QUATERNARY; PROTEIN SUBUNITS; PURINE-NUCLEOSIDE PHOSPHORYLASE; SEQUENCE HOMOLOGY, AMINO ACID;

MAMMALIA;

EID: 0036183496     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/0264-6021:3610001     Document Type: Review

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