The three-dimensional structures of nicotinate mononucleotide:5,6- dimethylbenzimidazole phosphoribosyltransferase (CobT) from Salmonella typhimurium complexed with 5,6-dimethybenzimidazole and its reaction products determined to 1.9 Å resolution

Biochemistry

Volumn 38, Issue 49, 1999, Pages 16125-16135

  Cheong, Cheom Gil ^a   Escalante Semerena, Jorge C ^a   Rayment, Ivan ^a  

^a UNIVERSITY OF WISCONSIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5,6 DIMETHYLBENZIMIDAZOLE; ALPHA RIBAZOLE; BACTERIAL ENZYME; BENZIMIDAZOLE DERIVATIVE; COBALAMIN DERIVATIVE; FLAVINE MONONUCLEOTIDE; NICOTINATE MONONUCLEOSIDE:5,6 DIMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSFERASE; NICOTINIC ACID; RIBOSE 5 PHOSPHATE; UNCLASSIFIED DRUG;

ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME SPECIFICITY; ENZYME STRUCTURE; HYDROPHOBICITY; NONHUMAN; PRIORITY JOURNAL; SALMONELLA TYPHIMURIUM; STRUCTURE ANALYSIS;

BENZIMIDAZOLES; BINDING SITES; CATALYSIS; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; MACROMOLECULAR SUBSTANCES; MODELS, MOLECULAR; MULTIENZYME COMPLEXES; NIACIN; NUCLEOTIDYLTRANSFERASES; PENTOSYLTRANSFERASES; PHOSPHORYLATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RIBONUCLEOTIDES; SALMONELLA TYPHIMURIUM; SUBSTRATE SPECIFICITY;

EID: 0033534156     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi991752c     Document Type: Article

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