Inosine - uridine nucleoside hydrolase from Crithidia fasciculata. Genetic characterization, crystallization, and identification of histidine 241 as a catalytic site residue

Biochemistry

Volumn 35, Issue 19, 1996, Pages 5963-5970

  Gopaul, Deshmukh N ^a   Meyer, Sheryl L ^a,b   Degano, Massimo ^a,c   Sacchettini, James C ^a   Schramm, Vern L ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b CEPHALON INC   (United States)

^c SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; HISTIDINE; INOSINE; NUCLEOSIDASE; RECOMBINANT PROTEIN; URIDINE;

AMINO ACID SEQUENCE; ARTICLE; CATALYSIS; CRITHIDIA FASCICULATA; ENZYME KINETICS; ENZYME PURIFICATION; ENZYME SPECIFICITY; ENZYME SUBSTRATE; ESCHERICHIA COLI; LEISHMANIA MAJOR; MOLECULAR CLONING; NONHUMAN; NUCLEIC ACID SYNTHESIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTOZOON; SITE DIRECTED MUTAGENESIS; X RAY DIFFRACTION;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CATALYSIS; CLONING, MOLECULAR; CRITHIDIA FASCICULATA; DNA, COMPLEMENTARY; ESCHERICHIA COLI; HISTIDINE; KINETICS; MOLECULAR SEQUENCE DATA; N-GLYCOSYL HYDROLASES; SEQUENCE HOMOLOGY, AMINO ACID; X-RAY DIFFRACTION;

EID: 0029869853     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi952998u     Document Type: Article

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