Effect of protease-activated receptor-2 deficiency on allergic dermatitis in the mouse ear

Japanese Journal of Pharmacology

Volumn 88, Issue 1, 2002, Pages 77-84

  Kawagoe, Junichi ^a   Takizawa, Toshiaki ^a   Matsumoto, Jiro ^a   Tamiya, Masaki ^a   Meek, Stephen E ^a   Smith, Andrew J H ^a   Hunter, Gary D ^a   Plevin, Robin ^a   Saito, Naohiro ^a   Kanke, Toru ^a   Fujii, Mikio ^a   Wada, Yasushi ^a  

^a KOWA COMPANY LTD   (Japan)

Author keywords

Allergic dermatitis; Contact hypersensitivity; Knockout mice; Passive cutaneous anaphylaxis; Protease activated receptor 2

Indexed keywords

OXAZOLONE; PICRYL CHLORIDE; PROTEINASE ACTIVATED RECEPTOR 2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD VESSEL PERMEABILITY; CONTACT DERMATITIS; CONTROLLED STUDY; DISEASE CLASSIFICATION; EAR DISEASE; EDEMA; FEMALE; HISTOPATHOLOGY; INFLAMMATORY INFILTRATE; MALE; MOUSE; NONHUMAN; PASSIVE SKIN ANAPHYLAXIS; PROTEIN DEFICIENCY; PROVOCATION TEST; SKIN ALLERGY; SKIN SENSITIZATION; SKINFOLD THICKNESS;

EID: 0036166557     PISSN: 00215198     EISSN: None     Source Type: Journal    
DOI: 10.1254/jjp.88.77     Document Type: Article

References (49)

1. Proteinase-activated receptors: Novel mechanisms of signaling by serine proteases
2. Proteinase-activated receptors
3. Protease-activated receptor (PAR), a novel family of G protein-coupled seven trans-membrane domain receptors: Activation mechanisms and physiological roles
4. Molecular cloning of potential proteinase activated receptor
5. Tissue factor- and factor X-dependent activation of protease-activated receptor 2 by factor VIIa
6. Evidence for the activation of PAR-2 by the sperm protease, acrosin: Expression of the receptor on oocytes
7. Purification and characterization of a trypsin-like serine proteinase from rat brain slices that degrades laminin and type IV collagen and stimulates protease-activated receptor-2
8. Differential regulation of human keratinocyte growth and differentiation by a novel family of protease-activated receptors
9. The protease-activated receptor 2 regulates pigmentation via keratinocyte-melanocyte interactions
10. Proteinase-activated receptor-2 in human skin: Tissue distribution and activation of keratinocytes by mast cell tryptase
11. Protease-activated receptor-2 involvement in hypotension in normal and endotoxemic rats in vivo
12. Increased expression of protease activated receptor-2 (PAR-2) in balloon-injured rat carotid artery
13. Protease-activated receptor-2 (PAR-2) is present in the rat hippocampus and is associated with neurodegeneration
14. Increased vascular permeability by a specific agonist of protease-activated receptor-2 in rat hindpaw
15. 2)-activating peptides in the rat paw
16. Human mast cell tryptase: A stimulus of microvascular leakage and mast cell activation
17. Agonists of proteinase-activated receptor 2 induce inflammation by a neurogenic mechanism
18. Protease-activated receptor-2 modulates myocardial ischemia-reperfusion injury in the rat heart
19. A protective role for protease-activated receptors in the airways
20. Protective effect of a PAR2-activating peptide on histamine-induced bronchoconstriction in guinea-pig
21. Evidence for selective effects of chronic hypertension on cerebral artery vasodilation to protease-activated receptor-2 activation
22. Proteinase-activated receptor-2-activating peptides induce leukocyte rolling, adhesion, and extravasation in vivo
23. Potent induction of a neutrophil and eosinophil-rich infiltrate in vivo by human mast cell tryptase: Selective enhancement of eosinophil recruitment by histamine
24. The role of mast cell tryptase in regulating endothelial cell proliferation, cytokine release, and adhesion molecule expression: Tryptase induces expression of mRNA for IL-1β and IL-8 and stimulates the selective release of IL-8 from human umbilical vein endothelial cells
25. Immunolocalization of protease-activated receptor-2 in skin: Receptor activation stimulates interleukin-8 secretion by keratinocytes in vitro
26. Proteinase-activated receptor-2-mediated activation of stress-activated protein kinases and inhibitory kappa B kinases in NCTC 2544 keratinocytes
27. Delayed onset of inflammation in protease-activated receptor-2-deficient mice
28. Endoglin, an ancillary TGFβ receptor, is required for extraembryonic angiogenesis and plays a key role in heart development
29. Two genetically separable steps in the differentiation of thymic epithelium
30. Antigenic competition in the induction of contact sensitivity in mice
31. Mouse ear PCA as a model for evaluating antianaphylactic agents
32. 1 antagonist with anti-puritic activities
33. Inhibition of allergic contact dermatitis to DNCB but not to oxazolone in interleukin-4-deficient mice
34. Pharmacological comparison of the immune and non-immune inflammations induced by picryl chloride and oxazolone in mice
35. Histology of and quantitative assays for oxazolone-induced allergic contact dermatitis in mice
36. Modulation of picryl chloride-induced contact hypersensitivity reaction in mice by nitric oxide
37. + T cells in murine contact sensitivity revealed by in vivo monoclonal antibody depletion
38. H1 clones
39. Signal transducer and activator of transcription 6 is essential in the induction of contact hypersensitivity
40. Effect of overproduction of interleukin 5 on dinitrofluorobenzene-induced allergic cutaneous response in mice
41. Impaired contact hypersensitivity to trinitrochlorobenzene in interleukin-4-deficient mice
42. Mice deficient in IL-1β manifest impaired contact hypersensitivity to trinitrochlorobenzene
43. Resistance to fever induction and impaired acute-phase response in interleukin-1β-deficient mice
44. Early and late reactions in contact sensitivity in the mouse
45. d mast cell-deficient mice
46. Passive cutaneous anaphylaxis in the mouse
47. Active cutaneous anaphylaxis (ACA) in the mouse ear
48. Characterization of protease-activated receptors in rat peritoneal mast cells
49. Management of atopic dermatitis