A major human arsenic metabolite, dimethylarsinic acid, requires reduced glutathione to induce apoptosis

Chemical Research in Toxicology

Volumn 15, Issue 5, 2002, Pages 629-637

  Sakurai, Teruaki ^a,b   Qu, Wei ^a   Sakurai, Masumi H ^a   Waalkes, Michael P ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^b TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACIVICIN; AMINOOXYACETIC ACID; ARSENIC DERIVATIVE; CACODYLIC ACID; ENZYME INHIBITOR; GAMMA GLUTAMYLTRANSFERASE; GLUTATHIONE; GLUTATHIONE REDUCTASE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CATALYSIS; CHEMICAL ANALYSIS; CYTOTOXICITY; DRUG MECHANISM; HISTOLOGY; LIVER CELL; METABOLITE; METHYLATION; NECROSIS; NONHUMAN; RAT;

ANIMALS; APOPTOSIS; ARSENITES; CACODYLIC ACID; CELL LINE; CHROMATOGRAPHY, THIN LAYER; DRUG INTERACTIONS; FLOW CYTOMETRY; GLUTATHIONE; HERBICIDES; HUMANS; LIVER; RATS; RATS, INBRED F344;

ANIMALIA; MAMMALIA; RODENTIA;

EID: 0036104528     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx0101604     Document Type: Article

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