Effect of glutathione depletion and metallothionein gene expression on arsenic-induced cytotoxicity and c-myc expression in vitro

Toxicological Sciences

Volumn 45, Issue 2, 1998, Pages 204-211

  Shimizu, Mitsuru ^a,b   Hochadel, James F ^a,c   Fulmer, Brandie A ^a   Waalkes, Michael P ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^b OSAKA CITY INSTITUTE OF PUBLIC HEALTH AND ENVIRONMENTAL SCIENCES   (Japan)

^c SAIC FREDERICK INC   (United States)

Author keywords

Arsenate; Arsenic; Arsenite; C myc; Glutathione; In vitro; Metallothionein; Rat

Indexed keywords

ARSENIC ACID; GLUTATHIONE; METALLOTHIONEIN;

ANIMAL CELL; ARTICLE; CELL SURVIVAL; CYTOTOXICITY; DNA SYNTHESIS INHIBITION; DRUG INDUCED DISEASE; GENE ACTIVATION; GENE EXPRESSION REGULATION; GENOTOXICITY; IN VITRO STUDY; MALIGNANT TRANSFORMATION; NONHUMAN; ONCOGENE C MYC; PROTO ONCOGENE;

ANIMALIA; RODENTIA;

EID: 0031739842     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1006/toxs.1998.2539     Document Type: Article

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