Surface thiols of human lymphocytes and their changes after in vitro and in vivo activation

Journal of Leukocyte Biology

Volumn 60, Issue 5, 1996, Pages 611-618

  Lawrence, David A ^a,b   Song, Renjie ^a   Weber, Peter ^a  

^a ALBANY MEDICAL COLLEGE   (United States)

^b WADSWORTH CENTER   (United States)

Author keywords

CD19; CD4; CD8; HIV; Oxidative; Sulfhydryl

Indexed keywords

BACITRACIN; BUTHIONINE SULFOXIMINE; CD18 ANTIGEN; CD19 ANTIGEN; CD4 ANTIGEN; CYCLOHEXIMIDE; DACTINOMYCIN; MEMBRANE ANTIGEN; MONENSIN; THIOL DERIVATIVE;

ARTICLE; CONTROLLED STUDY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; LYMPHOCYTE ACTIVATION; PRIORITY JOURNAL;

EID: 0029826005     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1002/jlb.60.5.611     Document Type: Article

References (82)

1. Ohara, H., Terasima, T. (1969) Variations of cellular sulfhydryl content during cell cycle of HeLa cells and its correlation to cyclic change of X-ray sensitivity. Exp. Cell Res. 58, 182-185.
2. Noelle, R. J., Lawrence, D. A. (1981) Modulation of T-cell functions. II. Chemical basis for the involvement of cell surface thiol-reactive sites in control of T-cell proliferation. Cell. Immunol. 60, 453-469.
3. Lawrence, D. A. (1981) Antigen activation of T cells. Handbook of Cancer Immunology, Vol. 8, 257-320.
4. Duncan, D. D., Lawrence, D. A. (1988) Four sulfhydryl-modifying compounds cause different structural damage but similar functional damage in murine lymphocytes. Chem. Biol. Int. 68, 137-152.
5. Ali, I. U., Hynes, R. O. (1978) Role of disulfide bonds in the attachment and function of large, external, transformation sensitive giycoprotein at the cell surface. Biochim. Biophys. Acta 510, 140-150.
6. Hynes, R. O., Destree, A. (1977) Extensive disulfide bonding at the mammalian cell surface. Proc. Natl. Acad. Sci. USA 74, 2855-2859.
7. Szent-Gyorgyi, A., Egyud, L. G., McLaughlin, J. A. (1967) Keto-aldehydes and cell division. Science 155, 539-541.
8. Merry, P., Winyard, P. G., Morris, C. J., Grootveld, M., Blake, D. R. (1989) Oxygen free radicals, inflammation, and synovitis: the current status. Ann. Rheumatol. Dis. 48, 864-870.
9. Richie J. P. (1992) The role of glutathione in aging and cancer. Exp. Gerontol. 27, 615-626.
10. Dröge, W. (1993) Cysteine and glutathione deficiency in AIDS patients: a rationale for the treatment with N-acetyl-cysteine. Pharmacology 46, 61-65.
11. Roederer, M., Staal, F. J., Anderson, M., Rabin, R., Raju, P. A., Herzenberg, L. A. (1993) Disregulalion of leukocyte glutathione in AIDS. Ann. NY Acad. Sci. 677, 113-125.
12. Buttke, T. M., Sandstrom, P. A. (1994) Oxidative stress as a mediator of apoptosis. Immunol. Today 15, 7-10.
13. Forrest, V. J., Kang, Y H., McClain, D. E., Robinson, D. H., Ramakrishnan, N. (1994) Oxidative stress-induced apoptosis prevented by Trolox. Free Rad. Biol. Med. 16, 675-684.
14. Hockenbery, D. M., Oltval, Z. N., Yin, X-M., Milliman, C. L., Korsmeyer, S. J. (1993) Bcl-2 functions in an antioxidant pathway to prevent apoptosis. Cell 75, 241-251.
15. Hockenbery, D. M. (1995) bcl-2, a novel regulator of cell death. Bioessays 17, 631-638.
16. Morse, M. L., Dahl, R. H. (1978) Cellular glutathione is a key to the oxygen effect in radiation damage. Nature 271, 660-662.
17. Duncan, D. D., Lawrence, D. A. (1991) Residual activation events functional after irradiation of mouse splenic lymphocytes. Radiat. Res. 125, 6-13.
18. d18. Noelle, R. J., Lawrence, D. A. (1981b) Determination of glutathione in lymphocytes and possible association of redox state and proliferative capacity of lymphocytes. Biochem. J. 198, 571-579.
19. Mehrishi, J. N., Zeiller, K. (1974) Surface molecular components of T and B lymphocytes. Eur. J. Immunol. 4, 474-478.
20. Freed, B. M., Lempert, N., Lawrence, D. A. (1991) Inhibition of interleukin-2 production in the human T cell line JURKAT by nonpolar maleimides. Toxicol. Appl. Pharmacol. 107, 173-182.
21. Noelle, R. J., Lawrence, D. A. (1980) Modulation of lymphocyte functions. I. 2-mercaptoethanol and macrophage effects on T-cell proliferation. Cell. Immunol. 50, 416-431.
22. Ryser, H. J., Levy, E. M., Mandel, R., DiSciullo, G. J. (1994) Inhibition of HIV infection by agents that interfere with thiol-disulfide interchange upon virus-receptor interaction. Proc. Natl. Acad. Sci. USA 91, 4559-4563.
23. Mandel, R., Ryser, H. J. P, Ghani, F., Wu, M., Peak, D. (1993) Inhibition of a reductive function of the plasma membrane by bacitracin and antibodies against protein disulfide-isomerase. Proc. Natl. Acad. Sci. USA 90, 4112-4116.
24. Roth, R. A. (1981) Bacitracin: an inhibitor of the insulin degrading activity of giutathione-insulin transhydrogenase. Biochem. Biophys. Res. Commun. 98, 431-438.
25. Buttke, T. M., Mallett, G. S., Steelman, L., McCubrey, J. A. (1989) Absence of unsaturated fatty acid synthesis in marine T lymphocytes. Proc. Natl. Acad. Sci. USA 86, 6133.
26. Link, G., Pinson, A., Hershko, C. (1993) Iron loading of cultured cardiac myocytes modifies sarcolemmal structure and increases lysosomal fragility. J. Lab. Clin. Med. 121, 127-134.
27. Manco, L., Amorim, A. (1993) Human erythrocyte pyrimidine 5′-nucleotidase isoenzymes: effect of sulfhydryl reagents and electrophoretic discrimination. Electrophoresis 14, 1084.
28. + -activated ATPase. XLVI. Effect of cation-induced conformational changes on sulfhydryl group modifica-tion. Biochim. Biophys. Acta 602, 144-154.
29. +-dependent amino acid transport. Biochim. Biophys. Acta 419, 93-103.
30. 2+-ATPase by dithiothreitol causes inhibition of phosphoenzyme isomerization in catalytic cycle. J. Biol. Chem. 269, 11060-11064.
31. Pelassy, C., Breittmayer, J. P., Ticchioni, M., Aussel, C. (1994) Effect of thimerisol on cytosolic calcium and phosphatidylserine synthesis in Jurkat T cells. Int. J. Biochem. 26, 93-96.
32. 2+-and phospholipid-independent activation of protein kinase C by selective oxidative modification of the regulatory domain. Proc. Natl. Acad. Sci. USA 86, 6758-6762.
33. Kass, G. E. N., Duddy, S. K., Orrenius, S. (1989) Activation of hepatocyte protein kinase C by redox-cycling quinones. Biochem. J. 260, 499-507.
34. Larsson, R., Cerutti, P. (1989) Translocation and enhancement of phosphotransferase activity of protein kinase C following exposure in mouse epidermal cells to oxidants. Cancer Res. 49, 5627-5632.
35. Wu, X. B., Brune, R, vonAppen, F., Ullrich, V. (1992) Reversible activation of soluble guanylate cyclase by oxidizing agents. Arch. Biochem. Biophys. 294, 75-82.
36. Ying, S. W., Miles, L., Pickering, D., Ye, M. (1992) Involvement of multiple sulfhydryl groups in melatonin signal transduction in chick brain. Mol. Cell. Endocrinol. 85, 53-63.
37. Duhe, R. J., Nielsen, M. D., Dittman, A. H., Villacres, E. C., Choi, E. J., Storm, D. R. (1994) Oxidation of critical cysteine residues of type I adenylyl cyclase by o-iodosobenzoate or nitric oxide reversibly inhibits stimulation by calcium and calmodulin. J. Biol. Chem. 269, 7290-7296.
38. Kanner, S. B., Kavanagh, T. J., Grossmann, A., Hu, S-K., Bolen, J. B., Rabinovitch, P. S., Ledbetter, J. A. (1992) Sulfhydryl oxidation down-regulales T-cell signaling and inhibits tyrosine phosphorylation of phospholipase Cγ1. Proc. Natl. Acad. Sci. USA 89, 300-304.
39. Rudd, C. E., Barber, E. K., Burgess, K. E., Hahn, J. Y., Odysseos, A. D., Sy, M. S., Schlossman, S. F. (1991) Molecular analysis of the interaction of P56lck with the CD4 and CD8 antigens. Adv. Exp. Med. Biol. 292, 85-96.
40. Collins, T. L., Uniyal, S., Shin, J., Strominger, J. L., Mittler, R. S., Burakoff, S. J. (1992) p561ck association with CD4 is required for the interaction between CD4 and the TCR/CD3 complex and for optimal antigen stimulation. J. Immunol. 148, 2159-2162.
41. Tagaya, Y., Maeda, Y., Mitsui, A., Kondo, N., Matsui, H., Hamuro, J., Brown, N., Arai, K., Yokota, T., Wakasugi, H. (1989) ATL-derived factor (ADF), an IL-2 receptor/Tac inducer homologous to thioredoxin; possible involvement of dithiol-reduction in the IL-2 receptor induction. Eur. Mol. Biol. Org. J. 8, 757-764.
42. Rudd, C. E., Janssen, O., Cai, Y-C., daSilva, A. J., Raab, M., Prasad, K. V. S. (1994) Two-step TCRζ/CD3-CD4 and CD28 signaling in T cells: SH2/SH3 domains, protein-tyrosine and lipid kinases. Immunol. Today 15, 225-234.
43. Chaudhri, G., Clark, I. A., Hunt, N. H., Cowden, W. B., Ceredig, R. (1986) Effect of antioxidants on primary alloantigen-induced T cell activation and proliferation. J. Immunol. 137, 2646-2652.
44. Fidelus, R. K. (1988) The generation of oxygen radicals: A positive signal for activation. Cell. Immunol. 113, 175-182.
45. Sekkat, C., Dornand, J., Gerber, M. (1988) Oxidative phenomena are implicated in human T-cell stimulation. Immunol. 63, 431-437.
46. Messina, J. M., Lawrence, D. A. (1992) Effects of 2-mercaptoethanol and buthionine sulfoximine on cysteine metabolism by and proliferation of mitogen-stimulated human and mouse lymphocytes. Int. J. Immunopharmacol. 14, 1221-1234.
47. Messina, J. P., Lawrence, D. A. (1989) Cell cycle progression of glutathione-depleted human peripheral blood mononuclear cells is inhibited at S phase. J Immunol. 143, 1974-1981.
48. Davies, P. J. A., Davies, D. R., Levitzki, A., Maxfield, F. R., Milhaud, P., Willingham, M. C., Pastan, I. H. (1980) Transglutaminase is essential in receptor-mediated endocytosis of alpha 2-macroglobulin and polypeptide hormones. Nature 283, 162-167.
49. Wong, W. S., Batt, C., Kinsella, J. E. (1990) Purification and characterization of rat liver transglutaminase. Int. J. Biochem. 22, 53-59.
50. Novogrodsky, A., Quittner, S., Rubin, A. L., Stenzel, K. H. (1978) Transglutaminase activity in human lymphocytes: early activation by phytomitogens. Proc. Natl. Acad. Sci. USA 75, 1157-1161.
51. Metafora, S., Peluso, G., Ravagnan, G., Fusco, A., Gentile, V., Porta, R. (1988) Implication of transglutaminase in mitogen-induced human lymphocyte blast transformation. Adv. Exp. Biol. Med. 231, 175-184.
52. Walsh, A.C., Michaud, S. G., Malossi, J. A., Lawrence, D. A. (1995) Glutathione depletion in human T lymphocytes: Analysis of activation-associated gene expression and the stress response. Toxicol. Appl. Pharmacol. 133, 249-261.
53. Eck, H. P., Gmunder, H., Hartmann, M., Petzoldt, D., Daniel, V., Dröge, W. (1989) Low concentrations of acid-soluble thiol (cysteine) in the blood plasma of HIV-1-infected patients. Biol. Chem. Hoppe-Seyler 370, 101-108.
54. + cell levels. J. Infect. Dis. 170, 771-781.
55. 2 production by macrophages infected with HIV. Cell. Immunol. 152, 120-130.
56. Telford, W. G., King, L. E., Fraker, P. J. (1992) Comparative evaluation of several DNA binding dyes in the detection of apoptosis-associated chromatin degradation by flow cytometry. Cytometry 13, 137-143.
57. + lymphocytes from human immunodeficiency virus-infected individuals. Blood 87, 4746-4753.
58. Kass, G. E. N., Duddy, S. K., Orrenius, S. (1989) Activation of hepatocyte protein kinase C by redox-cycling quinones. Biochem. J. 260, 499-507.
59. Larsson, R., Cerutti, P. (1989) Translocation and enhancement of phosphotransferase activity of protein kinase C following exposure in mouse epidermal cells to oxidants. Cancer Res. 49, 5627-5632
60. Wu, X. B., Brune, B., vonAppen, F., Ullrich, V. (1992) Reversible activation of soluble guanylate cyclase by oxidizing agents. Arch. Biochem. Biophys. 294, 75-82.
61. Ying, S. W., Niles, L., Pickering, D., Ye, M. (1992) Involvement of multiple sulfhydryl groups in melatonin signal transduction in chick brain. Mol. Cell. Endocrinol. 85, 53-63.
62. Duhe, R. J., Nielsen, M. D., Dittman, A. H., Villacres, E. C., Choi, E. J., Storm, D. R. (1994) Oxidation of critical cysteine residues of type I adenylyl cyclase by o-iodosobenzoate or nitric oxide reversibly inhibits stimulation by calcium and calmodulin. J. Biol. Chem. 269, 7290-7296.
63. Kanner, S. B., Kavanagh, T. J., Grossmann, A., Hu, S-K., Bolen, J. B., Rabinovitch, P. S., Ledbetter, J. A. (1992) Sulfhydryl oxidation down-regulates T-cell signaling and inhibits tyrosine phosphorylation of phospholipase Cγ1. Proc. Natl. Acad. Sci. USA 89, 300-304.
64. Rudd, C. E., Barber, E. K., Burgess, K. E., Hahn, J. Y., Odysseos, A. D., Sy, M. S., Schlossman, S. F. (1991) Molecular analysis of the interaction of P56lck with the CD4 and CD8 antigens. Adv. Exp. Med. Biol. 292, 85-96.
65. Collins, T. L., Uniyal, S., Shin, J., Strominger, J. L., Mittler, R. S., Burakoff, S. J. (1992) p56lck association with CD4 is required for the interaction between CD4 and the TCR/CD3 complex and for optimal antigen stimulation. J. Immunol. 148, 2159-2162.
66. Tagaya, Y., Maeda, Y, Mitsui, A., Kondo, N., Matsui, H., Hamuro, J., Brown, N., Arai, K., Yokota, T., Wakasugi, H. (1989) ATL-derived factor (ADF), an IL-2 receptor/Tac inducer homologous to thioredoxin; possible involvement of dithiol-reduction in the IL-2 receptor induction. Eur. Mol. Biol. Org. J. 8, 757-764.
67. Rudd, C. E., Janssen, O., Cai, Y-C., daSilva, A. J., Raab, M., Prasad, K. V. S. (1994) Two-step TCRζ/CD3-CD4 and CD28 signaling in T cells: SH2/SH3 domains, protein-tyrosine and lipid kinases. Immunol. Today 15, 225-234.
68. Chaudhri, G., Clark, I. A., Hunt, N. H., Cowden, W. B., Ceredig, R. (1986) Effect of antioxidants on primary alloantigen-induced T cell activation and proliferation. J. Immunol. 137, 2646-2652.
69. Fidelus, R. K. (1988) The generation of oxygen radicals: A positive signal for activation. Cell. Immunol. 113, 175-182.
70. Sekkat, C., Dornand, J., Gerber, M. (1988) Oxidative phenomena are implicated in human T-cell stimulation. Immunol. 63, 431-437.
71. Messina, J. M., Lawrence, D. A. (1992) Effects of 2-mercaptoethanol and buthionine sulfoximine on cysteine metabolism by and proliferation of mitogen-stimulated human and mouse lymphocytes. Int. J. Immunopharmacol. 14, 1221-1234.
72. Messina, J. P., Lawrence, D. A. (1989) Cell cycle progression of glutathione-depleted human peripheral blood mononuclear cells is inhibited at S phase. J. Immunol. 143, 1974-1981.
73. Davies, P. J. A., Davies, D. R., Levitzki, A., Maxfield, F. R., Milhaud, P., Willingham, M. C., Pastan, I. H. (1980) Transglutaminase is essential in receptor-mediated endocytosis of alpha 2-macroglobulin and polypeptide hormones. Nature 283, 162-167.
74. Wong, W. S., Batt, C., Kinsella, J. E. (1990) Purification and characterization of rat liver transglutaminase. Int. J. Biochem. 22, 53-59.
75. Novogrodsky, A., Quittner, S., Rubin, A. L., Stenzel, K. H. (1978) Transglutaminase activity in human lymphocytes: early activation by phytomitogens. Proc. Natl. Acad. Sci. USA 75, 1157-1161.
76. Metafora, S., Peluso, G., Ravagnan, G., Fusco, A., Gentile, V, Porta, R. (1988) Implication of transglutaminase in mitogen-induced human lymphocyte blast transformation. Adv. Exp. Biol. Med. 231, 175-184.
77. Walsh, A. C., Michaud, S. G., Malossi. J. A., Lawrence, D. A. (1995) Glutathione depletion in human T lymphocytes: Analysis of activation-associated gene expression and the stress response. Toxicol. Appl. Pharmacol. 133, 249-261.
78. Eck, H. P., Gmunder, H., Hartmann, M., Petzoldt, D., Daniel, V., Droge, W. (1989) Low concentrations of acid-soluble thiol (cysteine) in the blood plasma of HIV-1-infected patients. Biol. Chem. Hoppe-Seyler 370, 101-108.
79. + cell levels. J. Infect. Dis. 170, 771-781.
80. 2 production by macrophages infected with HIV. Cell. Immunol. 152, 120-130.
81. Telford, W. G., King, L. E., Fraker, P. J. (1992) Comparative evaluation of several DNA binding dyes in the detection of apoptosis-associated chromatin degradation by flow cytometry. Cytometry 13, 137-143.
82. + lymphocytes from human immunodeficiency virus-infected individuals. Blood 87, 4746-4753.