Role of renal cysteine conjugate β-lyase in the mechanism of compound A nephrotoxicity in rats

Anesthesiology

Volumn 86, Issue 1, 1997, Pages 160-171

  Kharasch, Evan D ^a   Thorning, David ^b   Garton, Kyle ^b   Hankins, Douglas C ^b   Kilty, Cormac G ^b  

^a UNIVERSITY OF WASHINGTON   (United States)

^b NONE

Author keywords

Anesthetics, volatile: sevoflurane; compound A.; Metabolism: glutathione; Toxicity: renal, kidney

Indexed keywords

SEVOFLURANE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; DOSE RESPONSE; DRUG DEGRADATION; DRUG PROTEIN BINDING; HISTOPATHOLOGY; KIDNEY BIOPSY; MALE; NEPHROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; TOXICITY TESTING;

AMINOOXYACETIC ACID; ANESTHETICS, INHALATION; ANIMALS; CARBON-SULFUR LYASES; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; ETHERS; HYDROCARBONS, FLUORINATED; ISOXAZOLES; KIDNEY; LYASES; MALE; METHYL ETHERS; PROBENECID; RATS; RATS, INBRED F344;

EID: 0031020994     PISSN: 00033022     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000542-199701000-00020     Document Type: Article

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