Regulation of nociceptive neurons by nerve growth factor and glial cell line derived neurotrophic factor

Canadian Journal of Physiology and Pharmacology

Volumn 80, Issue 5, 2002, Pages 495-505

  Priestley, J V ^a   Michael, G J ^a   Averill, S ^a   Liu, M ^a   Willmott, N ^a  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

CGRP; Dorsal root ganglion; IB4; Nociceptors; Vanilloid

Indexed keywords

CALCITONIN GENE RELATED PEPTIDE; CAPSAICIN; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; ISOPROTEIN; NERVE GROWTH FACTOR; SUBSTANCE P; VANILLOID RECEPTOR;

CELL POPULATION; CELL SIZE; CELL SUBPOPULATION; CONFERENCE PAPER; DOWN REGULATION; HUMAN; NERVE FIBER TRANSECTION; NOCICEPTION; NOCICEPTIVE RECEPTOR; NOCICEPTIVE STIMULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; SENSORY NERVE CELL; SIGNAL TRANSDUCTION; SPINAL GANGLION;

AFFERENT PATHWAYS; ANIMALS; CANNABINOIDS; GANGLIA, SPINAL; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR; HUMANS; NERVE GROWTH FACTOR; NERVE GROWTH FACTORS; NEUROGLIA; NEURONS; NOCICEPTORS; RECEPTORS, DRUG;

EID: 0036099051     PISSN: 00084212     EISSN: None     Source Type: Journal    
DOI: 10.1139/y02-034     Document Type: Conference Paper

References (114)

1. The tetrodotoxin-resistant sodium channel SNS has a specialized function in pain pathways
2. Sub-populations of smaller diameter trigeminal primary afferent neurons defined by expression of calcitonin gene-related peptide and the cell surface oligosaccharide recognized by monoclonal antibody LA4
3. The distribution of binding by isolectin I-B4 from Griffonia simplicifolia in the trigeminal ganglion and brainstem trigeminal nuclei in the rat
4. Immunocytochemical localization of trkA receptors in chemically identified subgroups of adult rat sensory neurons
5. Nerve growth factor modulates the activation status and fast axonal transport of ERK1/2 in adult nociceptive neurones
6. TrkA, CGRP and IB4 expression in retrogradely labeled cutaneous and visceral primary sensory neurons in the rat
7. Postnatal changes in the expression of the trkA high-affinity NGF receptor in primary sensory neurons
8. A distinct subgroup of small DRG cells express GDNF receptor components and GDNF is protective for these neurons after nerve injury
9. The glial cell line-derived neurotrophic factor family receptor components are differentially regulated within sensory neurons after nerve injury
10. Nerve growth-factor (NGF) differentially regulates the chemosensitivity of adult-rat cultured sensory neurons
11. 1D receptor mRNA differential co-localization with peptide mRNA in the guinea pig trigeminal ganglion
12. Potent analgesic effects of GDNF in neuropathic pain states
13. The expression of P2X(3) purinoreceptors in sensory neurons: Effects of axotomy and glial-derived neurotrophic factor
14. Myelinated fibres responding specificity to noxious stimulation of the skin
15. The capsaicin receptor: A heat-activated ion channel in the pain pathway
16. A capsaicin-receptor homologue with a high threshold for noxious heat
17. Impaired nociception and pain sensation in mice lacking the capsaicin receptor
18. Expression of mRNA for brain-derived neurotrophic factor in the dorsal root ganglion following peripheral inflammation
19. Bradykinin and nerve growth factor release the capsaicin receptor from PtdIns(4,5)P2-mediated inhibition
20. Glial-derived neurotrophic factor upregulates expression of functional SNS and NaN sodium channels and their currents in axotomized dorsal root ganglion neurons
21. Dynamic pattern of Reg-2 expression in rat sensory neurones following peripheral nerve injury
22. Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia
23. Neurotrophins and adult somatosensory neurons
24. Plasticity of sodium channel expression in DRG neurons in the chronic constriction injury model of neuropathic pain
25. Increased content and transport of substance P and calcitonin gene-related peptide in sensory nerves innervating inflamed tissue: Evidence for a regulatory function of nerve growth factor in vivo
26. Differential role of GDNF and NGF in the maintenance of two TTX-resistant sodium channels in adult DRG neurons
27. Localization of the tetrodotoxin-resistant sodium channel NaN in nociceptors
28. Neurotrophin signaling via trks and p75
29. Transport and localization of the DEG/ENaC ion channel BNaC1alpha to peripheral mechanosensory terminals of dorsal root ganglia neurons
30. Growth responses of different subpopulations of adult sensory neurons to neurotrophic factors in vitro
31. A possible role for nerve growth factor in the augmentation of sodium channels in models of chronic pain
32. ATP as a peripheral mediator of pain
33. GDNF mRNA in Schwann cells and DRG satellite cells after chronic sciatic nerve injury
34. Localization of central cannabinoid CB1 receptor messenger RNA in neuronal subpopulations of rat dorsal root ganglia: A double-label in situ hybridization study
35. Expression of glial cell line-derived neurotrophic factor family of growth factors in peripheral nerve injury in rats
36. Messenger plasticity in primary sensory neurons following axotomy and its functional implications
37. Immunocytochemical localization of GDNF in primary afferents of the lumbar dorsal horn
38. The molecular dynamics of pain control
39. Cutaneous thermoreceptors in primates and sub-primates
40. Intrathecally delivered glial cell line-derived neurotrophic factor produces electrically evoked release of somatostatin in the dorsal horn of the spinal cord
41. GDNF-related factor persephin is widely distributed throughout the nervous system
42. Primary sensory neurons of the rat showing calcitonin gene- related peptide immunoreactivity and their relation to substance P-, somatostatin-, galanin-, vasoactive intestinal polypeptide- and cholecystokinin-immunoreactive ganglion cells
43. Anatomical evidence supporting the potential for modulation by multiple neurotrophins in the majority of adult lumbar sensory neurons
44. Coexpression of trk family members and low-affinity neurotrophin receptors in rat dorsal-root ganglion neurons
45. Gene expression of histamine H1 receptor in guinea pig primary sensory neurons: A relationship between H1 receptor mRNA-expressing neurons and peptidergic neurons
46. Brain-derived neurotrophic factor modulates nociceptive sensory inputs and NMDA-evoked responses in the rat spinal cord
47. Properties of somata of spinal dorsal root ganglion cells differ according to peripheral receptor innervated
48. Fine structure of myelinated mechanical nociceptor endings in cat hairy skin
49. Peripheral patterns of calcitonin-gene-related peptide general somatic sensory innervation: Cutaneous and deep terminations
50. Morphological and biochemical cell types of sensory neurons
51. Soma neurofilament immunoreactivity is related to cell size and fibre conduction velocity in rat primary sensory neurons
52. Correlation of CGRP-like immunoreactivity (CGRP-LI) with sensory receptor properties in dorsal root ganglion (DRG) neurons in guinea pigs
53. Relationship of substance P to afferent characteristics of dorsal root ganglion neurones in guinea-pig
54. Analysis of the retrograde transport of glial cell line-derived neurotrophic factor (GDNF), neurturin, and persephin suggests that in vivo signaling for the GDNF family is GFRalpha coreceptor-specific
55. Brain-derived neurotrophic factor is released in the dorsal horn by distinctive patterns of afferent fiber stimulation
56. Increased mRNA expression of the B1 and B2 bradykinin receptors and antinociceptive effects of their antagonists in an animal model of neuropathic pain
57. Peripheral and central mechanisms of NGF-induced hyperalgesia
58. GDNF in a bind with known orphan: Accessory implicated in new twist
59. Neurotrophic factors - From molecule to man
60. Comparison of functional capsaicin responses and their relationship to the expression of VR1 receptors in IB4-positive and negative sensory neurons
61. Preserved pain and reduced neuropathic pain in mice lacking PKCgamma
62. Neurotrophins: Peripherally and centrally acting modulators of tactile stimulus-induced inflammatory pain hypersensitivity
63. Inhibition of hyperalgesia by ablation of lamina 1 spinal neurons expressing the substance P receptor
64. Cell type and conduction velocity of rat primary sensory neurons with substance P-like immunoreactivity
65. Cell type and conduction velocity of rat primary sensory neurons with calcitonin gene-related peptide-like immunoreactivity
66. NGF as a mediator of inflammatory pain
67. Expression and coexpression of trk receptors in subpopulations of adult primary sensory neurons projecting to identified peripheral targets
68. The biological effects of endogenous NGF in adult sensory neurons revealed by a trkA-IgG fusion molecule
69. Differential expression of the mRNA for the vanilloid receptor subtype 1 in cells of the adult rat dorsal root and nodose ganglia and its downregulation by axotomy
70. Nerve growth factor treatment increases brain-derived neurotrophic factor selectively in trkA-expressing dorsal root ganglion cells and in their central terminations within the spinal cord
71. Persephin, a novel neurotrophic factor related to GDNF and neurturin
72. IB4-binding DRG neurons switch from NGF to GDNF dependence in early postnatal life
73. Cells in laminae III and IV of the rat spinal cord that possess the neurokinin-1 receptor and have dorsally directed den-drites receive a major synaptic input from tachykinin-containing primary afferents
74. Differential regulation of mRNAs for GDNF and its receptors Ret and GDNFR alpha after sciatic nerve lesion in the mouse
75. Peripheral inflammation increases the capsaicin sensitivity of dorsal root ganglion neurons in a nerve growth factor-dependent manner
76. Glial cell line derived neurotrophic factor (GDNF) regulates VR1 and substance P in cultured sensory neurons
77. Regulation of expression of the sensory neuron-specific sodium channel SNS in inflammatory and neuropathic pain
78. GFRalpha3 is expressed predominantly in nociceptive sensory neurons
79. Differences in expression of oligosaccharides, neuropeptides, carbonic anhydrase and neurofilament in rat primary afferent neurons retrogradely labelled via skin, muscle or visceral nerves
80. Depletion of hematogenous macrophages promotes partial hindlimb recovery and neuroanatomical repair after experimental spinal cord injury
81. An immunohistochemical and quantitative examination of dorsal root ganglion neuronal subpopulations
82. The mammalian sodium channel BNC1 is required for normal touch sensation
83. Ultrastructural and neurochemical analysis of synaptic input to trigemino-thalamic projection neurones in lamina I of the rat: A combined immunocytochemical and retrograde labelling study
84. Nerve growth factor induces P2X(3) expression in sensory neurons
85. Contribution of interleukin-1 beta to the inflammation-induced increase in nerve growth factor levels and inflammatory hyperalgesia
86. Intracellular signaling pathways activated by neurotrophic factors
87. Acid phosphatase as a selective marker for a class of small sensory ganglion cells in several mammals: Spinal cord distribution, histochemical properties, and relation to fluoride- resistant acid phosphatase (FRAP) of rodents
88. Selective neuronal glycoconjugate expression in sensory and autonomic ganglia: Relation of lectin reactivity to peptide and enzyme markers
89. Intradermal injection of capsaicin in humans produces degeneration and subsequent reinnervation of epidermal nerve fibers: Correlation with sensory function
90. Functions of the neurotrophins during nervous system development - What the knockouts are teaching us
91. Tackling pain at the source: New ideas about nociceptors
92. Evidence for glycoconjugate in nociceptive primary sensory neurons and its origin from the Golgi complex
93. Isolectin B(4)-positive and -negative nociceptors are functionally distinct
94. The GDNF/RET signaling pathway and human diseases
95. SNS Na+ channel expression increases in dorsal root ganglion neurons in the carrageenan inflammatory pain model
96. Nervous system distribution of the serotonin 5-HT3 receptor mRNA
97. The cloned capsaicin receptor integrates multiple pain-producing stimuli
98. Peripheral expression and biological activities of GDNF, a new neurotrophic factor for avian and mammalian peripheral neurons
99. Complementary and overlapping expression of glial cell line-derived neurotrophic factor (GDNF), c-ret proto-oncogene, and GDNF receptor-alpha indicates multiple mechanisms of trophic actions in the adult rat CNS
100. Prostaglandins and cycloxygenases in the spinal cord
101. Influence of nerve growth factor on neurofilament gene expression in mature primary sensory neurons
102. Differential influence of nerve growth factor on neuropeptide expression in vivo: A novel role in peptide suppression in adult sensory neurons
103. P2X3 is expressed by DRG neurons that terminate in inner lamina II
104. H(+)-gated cation channels: Neuronal acid sensors in the NaC/DEG family of ion channels
105. Neurturin and glial cell line-derived neurotrophic factor receptor-beta (GDNFR-beta), novel proteins related to GDNF and GDNFR-alpha with specific cellular patterns of expression suggesting roles in the developing and adult nervous system and in peripheral organs
106. Nerve growth factor (NGF) regulates adult rat cultured dorsal root ganglion neuron responses to the excitotoxin capsaicin
107. Phenotypic modification of primary sensory neurons - The role of nerve growth-factor in the production of persistent pain
108. Nerve growth factor contributes to the generation of inflammatory sensory hypersensitivity
109. Expression of the 5-HT1B receptor by subtypes of rat trigeminal ganglion cells
110. Bradykinin B1 receptor is constitutively expressed in the rat sensory nervous system
111. Neurotrophin receptor mRNA expression defines distinct populations of neurons in rat dorsal root ganglia
112. Complementary distribution of receptors for neurotensin and NPY in small neurons in rat lumbar DRGs and regulation of the receptors and peptides after peripheral axotomy
113. CGRP immunoreactive neurons in rat dorsal root ganglia do not all contain low affinity NGF receptor immunoreactivity
114. Anandamide - The other side of the coin