GDNF-related factor persephin is widely distributed throughout the nervous system

Journal of Neuroscience Research

Volumn 53, Issue 4, 1998, Pages 494-501

  Jaszai, Jozsef ^b   Farkas, Lilla ^b   Galter, Dagmar ^b   Reuss, Bernhard ^b   Strelau, Jens ^b   Unsicker, Klaus ^b   Krieglstein, Kerstin ^a,b  

^a Dept of Anat and Cell Biology III   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Astroglia; Glial cell line derived neurotrophic factor; Motoneurons; Oligodendrocytes; Optic nerve; Peripheral ganglia

Indexed keywords

GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; MESSENGER RNA;

ADRENAL GLAND; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN CORTEX; CELL STRAIN; CELLULAR DISTRIBUTION; CEREBELLUM; CONTROLLED STUDY; CORPUS STRIATUM; HIPPOCAMPUS; NERVOUS SYSTEM; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; SPINAL CORD; SPINAL GANGLION; SUPERIOR CERVICAL GANGLION; TISSUE DISTRIBUTION;

ADRENAL GLAND NEOPLASMS; ANIMALS; ANIMALS, NEWBORN; ASTROCYTES; BASE SEQUENCE; BRAIN; CLONING, MOLECULAR; DNA, COMPLEMENTARY; GANGLIA, SPINAL; INTRONS; KIDNEY; MOLECULAR SEQUENCE DATA; NERVE GROWTH FACTORS; NERVE TISSUE PROTEINS; NEURONS; OLIGODENDROGLIA; OPTIC NERVE; ORGAN SPECIFICITY; PC12 CELLS; PHEOCHROMOCYTOMA; RATS; RATS, SPRAGUE-DAWLEY; RECOMBINANT PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SCIATIC NERVE; SEQUENCE ANALYSIS, DNA; SPINAL CORD; SUPERIOR CERVICAL GANGLION;

EID: 0031879362     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4547(19980815)53:4<494::AID-JNR12>3.0.CO;2-2     Document Type: Article

References (38)

1. Acheson A, Lindsay RM (1996): Non target-derived roles of neurotrophins. Phil Trans R Soc Lond 351:417-422.
2. Baloh RH, Tansey MG, Golden JP, Creedon DJ, Heuckeroth RO, Keck CL, Zimonjic DB, Popescu NC, Johnson EM, Jr., Milbrandt J (1997): TrnR2, a novel receptor that mediates neurturin and GDNF signaling through Ret. Neuron 18:793-802.
3. Beck KD, Valverde J, Alexi T, Poulsen K, Moffat B, Vandlen RA, Rosenthal A, Hefti F (1995): Mesencephalic dopaminergic neurons protected by GDNF from axotomy-induced degeneration in the adult brain. Nature 373:339-341.
4. Behar T, McMorris FA, Novotny EA, Barker JL, Dubois-Dalcq M (1988): Growth and differentiation properties of O-2A progenitors purified from rat cerebral hemispheres. J Neurosci Res 21:168-180.
5. Camu W, Henderson CE (1992): Purification of embryonic rat motoneurons by panning on a monoclonal antibody to the low-affinity NGF receptor. J Neurosci Meth 44:59-70.
6. Choi-Lundberg DL, Bohn MC (1995): Ontogeny and distribution of glial cell line-derived neurotrophic factor (GDNF) mRNA in rat. Brain Res Dev Brain Res 85:80-88.
7. Creedon DJ, Tansey MG, Baloh RH, Osborne, PA, Lampe PA, Fahrner TJ, Heuckeroth RO, Milbrandt J, Johnson EM, Jr. (1997): Neurturin shares receptors and signal transduction pathways with glial cell line-derived neurotrophic factor in sympathetic neurons. Proc Natl Acad Sci USA 94:7018-7023.
8. Flanders KC, Lüdecke G, Engels S, Cissel DS, Roberts AB, Kondaiah P, Lafyatis R, Sporn MB, Unsicker K (1991) Immunhistochemical localization of transforming growth factor-βs in the nervous system of the mouse embryo. Development 113:183-191.
9. Flanders KC, Lüdecke G, Renzig J, Hamm C, Cissel DS, Unsicker K (1993): Effect of TGF-βs and bFGF on astroglial cell growth and gene expression in vitro. Mol Cell Neurosci 4:406-417.
10. Gash DM, Zhang Z, Ovadia A, Cass WA, Yi A, Simmerman L, Russell D, Martin D, Lapchak PA, Collins F, Hoffer BJ, Gerhardt GA (1996): Functional recovery in parkinsonian monkeys treated with GDNF. Nature 380:252-255.
11. Henderson CE, Phillips HS, Pollock RA, Davies AM, Lemeulle C, Armanini M, Simmons L, Moffet B, Vandlen RA, Simpson LC, Moffet B, Vandlen RA, Koliatsos VE, Rosenthal A (1994): GDNF: A potent survival factor for motoneurons present in peripheral nerve and muscle. Science 266:1062-1064.
12. Heuckeroth RO, Tourtellotte L, Gavrilina G, Johnson E, Milbrandt J (1997): Characterization of the neurturin knockout mouse. Soc Neu rosci Abstr 23:1704.
13. Jing S, Wen D, Yu Y, Hoist PL, Luo Y, Fang M, Tamir R, Antonio L, Hu Z, Cuppies R, Louis JC, Hu S, Altrock BW, Fox GM (1996): GDNF-induced activation of the ret protein tyrosine kinase is mediated by GDNFR-alpha, a novel receptor for GDNF. Cell 85:1113-1124.
14. Jing S, Yu Y, Fang M, Hu Z, Holst PL, Boone T, Delaney J, Schultz H, Zhou R, Fox GM (1997): GFRalpha-2 and GFRalpha-3 are two new receptors for ligands of the GDNF family. J Biol Chem. 272:33111-33117.
15. Klein RD, Sherman D, Ho WH, Stone D, Bennett GL, Moffat B, Vandlen R, Simmons L, Gu Q, Hongo JA, Devaux B, Poulsen K, Armanini M, Nozaki C, Asai N, Goddard A, Phillips H, Henderson CE, Takahashi M, Rosenthal A (1997): A GPI-linked protein that interacts with Ret to form a candidate neurturin receptor. Nature 387:717-721.
16. Kotzbauer PT, Lampe PA, Heuckeroth RO, Golden JP, Creedon DJ, Johnson EM, Jr., Milbrandt J (1996): Neurturin, a relative of glial-cell-line-derived neurotrophic factor. Nature 384:467-470.
17. Krieglstein K, Rufer M, Suter-Crazzolara C, Unsicker K (1995): Neural functions of the transforming growth factor β. Int J Dev Neurosci 13:301-315.
18. Levi-Montalcini R (1987): The nerve growth factor 35 years later. Science 237:1154-1162.
19. Krieglstein K, Deimling F, Suter-Crazzolara C, Unsicker K (1996): Expression and localization of GDNF in developing and adult adrenal chromaffin cells. Cell Tiss Res 286:263-268.
20. Lin LF, Doherty DH, Lile JD, Bektesh S, Collins F (1993): GDNF: A glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons. Science 260:1130-1132.
21. Masure S, Cik M, Pangalos MN, Bonaventure P, Verhasselt P, Lesage AS, Leysen JE, Gordon RD (1998): Molecular cloning, expression and tissue distribution of glial-cell-line-derived neurotrophic factor family receptor alpha-3 (GFRalpha-3). Eur J Biochem. 251:622-630.
22. McCarthy KD, de Vellis J (1980): Preparation of separate astroglial and oligodendroglia cell cultures from rat cerebral tissue. J Cell Biol 85:890-892.
23. McKinnon RD, Piras G, Ida JA, Dubois-Dalcq M (1993): A role for TGF-β in oligodendrocyte differentiation. J Cell Biol 121:1397-1407.
24. Milbrandt J, de Sauvage FJ, FahrnerTJ, Baloh RH, Leitner ML, Tansey MG, Lampe PA, Heuckeroth RO, Kotzbauer PT, Simburger KS, Golden JP, Davies JA, Vejsada R, Kato AC, Hynes M, Sherman D, Nishimura M, Wang L-C, Vandlen R, Moffat B, Klein RD, Poulsen K, Gray C, Garces A, Henderson CE, Philips HS, Johnson EM Jr. (1998): Persephin, a novel neurotrophic factor related to GDNF and neurturin. Neuron 20:245-253.
25. Pochon NA, Menoud A, Tseng JL, Zurn AD, Aebischer P (1997): Neuronal GDNF expression in the adult rat nervous system identified by in situ hybridization. Eur J Neurosci 9:463-471.
26. Raff MC, Williams BP, Miller RH (1984): The in vitro differentiation of a bipotential glial progenitor cell. The EMBO Journal 3:1857-1864.
27. Reuss B, Dermitzel R, Unsicker K (1998): Fibroblast growth factor 2 (FGF-2) differentially regulates connexin (ex) 43 expression and function in astroglial cells from distinct brain regions. Glia 22:19-30.
28. Sainio K, Suvanto P, Davies J, Wartiovaara J, Wartiovaara K, Saarma M, Arumae U, Meng X, Lindahl M, Pachnis V, Sariola H (1997): Glial-cell-line-derived neurotrophic factor is required for bud initiation from ureteric epithelium. Development 124: 4077-1087.
29. Sanicola M, Hession C, Worley D, Carmillo P, Ehrenfels C, Walus L, Robinson S, Jaworski G, Wei H, Tizard R, Whitty A, Pepinsky RB, Cate RL (1997): Glial cell line-derived neurotrophic factor-dependent RET activation can be mediated by two different cell-surface accessory proteins. Proc Natl Acad Sci USA 94:6238-6243.
30. Tomac A, Widenfalk J, Lin LF, Kohno T, Ebendal T, Hoffer BJ, Olson L (1995): Retrograde axonal transport of glial cell line-derived neurotrophic factor in the adult nigrostriatal system suggests a trophic role in the adult. Proc Natl Acad Sci USA 92:8274-8278.
31. Treanor JJ, Goodman L, de Sauvage F, Stone DM, Poulsen KT, Beck CD, Gray C, Armanini MP, Pollock RA, Hefti F, Phillips HS, Goddard A, Moore MW, Buj Bello A, Davies AM, Asai N, Takahashi M, Vandlen R, Henderson CE, Rosenthal A (1996): Characterization of a multicomponent receptor for GDNF. Nature 382:80-83.
32. Trupp M, Ryden M, Jornvall H, Funakoshi H, Timmusk T, Arenas E, Ibanez CF (1995): Peripheral expression and biological activities of GDNF, a new neurotrophic factor for avian and mammalian peripheral neurons. J Cell Biol 130:137-148.
33. Trupp M, Arenas E, Fainzilber M, Nilsson AS, Sieber BA, Grigoriou M, Kilkenny C, Salazar Grueso E, Pachnis V, Arumäe U, Sariola H, Saarma M, Ibanez CF (1996): Functional receptor for GDNF encoded by the c-ret proto-oncogene. Nature 381:785-788.
34. Unsicker K, Flanders KC, Cissel DS, Lafyatis R, Sporn MB (1991): Transforming growth factor beta isoforms in the adult rat central and peripheral nervous system. Neuroscience 44:613-625.
35. Unsicker K, Suter-Crazzolara C, Krieglstein K (1998): Neurotrophic roles of GDNF and related factors. In Hefti F (ed): "Handbook of Experimental Pharmacology: Neurotrophic Factor Pharmacology." Berlin: Springer-Verlag, pp. 189-224.
36. Widenfalk J, Nosrat C, Tomac A, Westphal H, Hoffer B, Olson L (1997): Neurturin and glial cell line-derived neurotrophic factor receptor-β (GDNFR-β), novel proteins related to GDNF and GDNFR-α with specific cellular patterns of expression suggesting roles in the developing and adult nervous system and in peripheral organs. J Neurosci 17:8506-8519.
37. Worby CA, Vega QC, Chao HH, Seasholtz AF, Thompson RC, Dixon JE (1998): Identification and characterization of GFRalpha-3, a novel Co-receptor belonging to the glial cell line-derived neurotrophic receptor family. J Biol Chem. 273:3502-3508.
38. Yan Q, Matheson C, Lopez OT (1995): In vivo neurotrophic effects of GDNF on neonatal and adult facial motor neurons. Nature 373:341-344.