메뉴 건너뛰기




Volumn 49, Issue 1, 2002, Pages 121-128

TEL/JAK2 tyrosine kinase inhibits DNA repair in the presence of amifostine

Author keywords

Amifostine, idarubicin; Comet assay; DnA damage; DNA repair; Oncogenic tyrosine kinase; TEL JAK2

Indexed keywords

MURINAE;

EID: 0036048892     PISSN: 0001527X     EISSN: None     Source Type: Journal    
DOI: 10.18388/abp.2002_3828     Document Type: Article
Times cited : (7)

References (30)
  • 1
    • 0027970838 scopus 로고
    • Chromosomal translocations in human cancer
    • Rabbitts, T.H. (1994) Chromosomal translocations in human cancer. Nature 372, 143-149.
    • (1994) Nature , vol.372 , pp. 143-149
    • Rabbitts, T.H.1
  • 2
    • 0030852328 scopus 로고    scopus 로고
    • Fusion of TEL, the ETS-variant gene 6 (ETV6), to the receptor-associated kinase JAK2 as a result of the t(9;12) in a lymphoid and t(9;15;12) in a myeloid leukemia
    • Peeters, P., Raynaud, S.D., Cools, J., Wlodarska, I., Grosgeorge, J., Philip, P., Monpoux, F., Van Rompaey, L., Baens, M., Van den Berghe, H. & Marynen, P. (1997) Fusion of TEL, the ETS-variant gene 6 (ETV6), to the receptor-associated kinase JAK2 as a result of the t(9;12) in a lymphoid and t(9;15;12) in a myeloid leukemia. Blood 90, 2535-2540.
    • (1997) Blood , vol.90 , pp. 2535-2540
    • Peeters, P.1    Raynaud, S.D.2    Cools, J.3    Wlodarska, I.4    Grosgeorge, J.5    Philip, P.6    Monpoux, F.7    Van Rompaey, L.8    Baens, M.9    Van Den Berghe, H.10    Marynen, P.11
  • 3
    • 0033614446 scopus 로고    scopus 로고
    • Chronic myeloid leukemia
    • Sawyers, C.L. (1999) Chronic myeloid leukemia. N. Engl. J. Med. 340, 1330-1340.
    • (1999) N. Engl. J. Med. , vol.340 , pp. 1330-1340
    • Sawyers, C.L.1
  • 4
    • 0029926755 scopus 로고    scopus 로고
    • Signaling by the cytokine receptor superfamily in normal and transformed hematopoietic cells
    • Ihle, J.N. (1996) Signaling by the cytokine receptor superfamily in normal and transformed hematopoietic cells. Cancer Res. 68, 23-65.
    • (1996) Cancer Res. , vol.68 , pp. 23-65
    • Ihle, J.N.1
  • 7
    • 0032530972 scopus 로고    scopus 로고
    • Transformation of hematopoietic cell lines to growth-factor independence and induction of a fatal myelo-and lymphoproliferative disease in mice by retrovirally transduced TEL/JAK2 fusion genes
    • Schwaller, J., Frantsve, J., Aster, J., Williams, I.E., Tomasson, M.H., Ross, T.S., Peeters, P., Van Rompaey, L., Van Etten, R.A., Ilaria, R., Jr., Marynen, P. & Gilliland, D.G. (1998) Transformation of hematopoietic cell lines to growth-factor independence and induction of a fatal myelo-and lymphoproliferative disease in mice by retrovirally transduced TEL/JAK2 fusion genes. EMBO J. 17, 5321-5333.
    • (1998) EMBO J. , vol.17 , pp. 5321-5333
    • Schwaller, J.1    Frantsve, J.2    Aster, J.3    Williams, I.E.4    Tomasson, M.H.5    Ross, T.S.6    Peeters, P.7    Van Rompaey, L.8    Van Etten, R.A.9    Ilaria R., Jr.10    Marynen, P.11    Gilliland, D.G.12
  • 9
    • 0344517071 scopus 로고    scopus 로고
    • Fusion of the ets transcription factor TEL to Jak2 results in constitutive Jak-Stat signaling
    • Ho, J.M., Beattie, B.K., Squire, J.A., Frank, D.A. & Barber, D.L. (1999) Fusion of the ets transcription factor TEL to Jak2 results in constitutive Jak-Stat signaling. Blood 93, 4354-4364.
    • (1999) Blood , vol.93 , pp. 4354-4364
    • Ho, J.M.1    Beattie, B.K.2    Squire, J.A.3    Frank, D.A.4    Barber, D.L.5
  • 10
    • 0035980056 scopus 로고    scopus 로고
    • TEL-JAK2 mediates constitutive activation of the phosphatidylinositol 3′-kinase/protein kinase B signaling pathway
    • Nguyen, M.H., Ho, J.M., Beattie, B.K. & Barber, D.L. (2001) TEL-JAK2 mediates constitutive activation of the phosphatidylinositol 3′-kinase/protein kinase B signaling pathway. J. Biol. Chem. 276, 32704-32713.
    • (2001) J. Biol. Chem. , vol.276 , pp. 32704-32713
    • Nguyen, M.H.1    Ho, J.M.2    Beattie, B.K.3    Barber, D.L.4
  • 11
    • 0035036625 scopus 로고    scopus 로고
    • Socs-1 inhibits TEL-JAK2-mediated transformation of hematopoietic cells through inhibition of JAK2 kinase activity and induction of proteasome-mediated degradation
    • Frantsve, J., Schwaller, J., Sternberg, D.W., Kutok, J. & Gilliland, D.G. (2001) Socs-1 inhibits TEL-JAK2-mediated transformation of hematopoietic cells through inhibition of JAK2 kinase activity and induction of proteasome-mediated degradation. Mol. Cell. Biol. 21, 3547-3557.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 3547-3557
    • Frantsve, J.1    Schwaller, J.2    Sternberg, D.W.3    Kutok, J.4    Gilliland, D.G.5
  • 12
    • 0036261727 scopus 로고    scopus 로고
    • Fusion tyrosine kinases induce therapeutic drug resistance by stimulation of homology-dependent recombination repair, prolongation of G2/M phase and protection from apoptosis
    • in press
    • Slupianek, A., Hoser, G., Majsterek, I., Bronisz, A., Malecki, M., Fishel, R., Blasiak, J. & Skorski, T. (2002) Fusion tyrosine kinases induce therapeutic drug resistance by stimulation of homology-dependent recombination repair, prolongation of G2/M phase and protection from apoptosis. Mol. Cell. Biol. (in press).
    • (2002) Mol. Cell. Biol.
    • Slupianek, A.1    Hoser, G.2    Majsterek, I.3    Bronisz, A.4    Malecki, M.5    Fishel, R.6    Blasiak, J.7    Skorski, T.8
  • 13
    • 0025653684 scopus 로고
    • DNA topoisomerases as anticancer drug targets
    • Schneider, E., Hsiang, Y. & Liu, L.F. (1990) DNA topoisomerases as anticancer drug targets. Adv. Pharmacol. 21, 149-183.
    • (1990) Adv. Pharmacol. , vol.21 , pp. 149-183
    • Schneider, E.1    Hsiang, Y.2    Liu, L.F.3
  • 14
    • 0032840176 scopus 로고    scopus 로고
    • Comparative cardiotoxicity of idarubicin and doxorubicin using the isolated perfused rat heart model
    • Platel, D., Pouna, P., Bonoron-Adele, D. & Robert, J. (1999) Comparative cardiotoxicity of idarubicin and doxorubicin using the isolated perfused rat heart model. Anticancer Drugs 10, 671-676.
    • (1999) Anticancer Drugs , vol.10 , pp. 671-676
    • Platel, D.1    Pouna, P.2    Bonoron-Adele, D.3    Robert, J.4
  • 15
    • 0029582850 scopus 로고
    • Involvement of the polyamine transport system in cellular uptake of the radioprotectants WR-1065 and WR-33278
    • Mitchell, J.L.A., Judd, G.G., Diveley, R.R., Choe, C.Y. & Leyser, A. (1995) Involvement of the polyamine transport system in cellular uptake of the radioprotectants WR-1065 and WR-33278. Carcinogenesis 16, 3063-3068.
    • (1995) Carcinogenesis , vol.16 , pp. 3063-3068
    • Mitchell, J.L.A.1    Judd, G.G.2    Diveley, R.R.3    Choe, C.Y.4    Leyser, A.5
  • 17
    • 0026588374 scopus 로고
    • N-(2-mercaptoethyl)-1,3-propanediamine (WR-1065) protects thymocytes from programmed cell death
    • Ramakrishnan, N. & Catravas, G.N. (1992) N-(2-mercaptoethyl)-1,3-propanediamine (WR-1065) protects thymocytes from programmed cell death. J. Immunol. 148, 1817-1821.
    • (1992) J. Immunol. , vol.148 , pp. 1817-1821
    • Ramakrishnan, N.1    Catravas, G.N.2
  • 18
    • 0031410502 scopus 로고    scopus 로고
    • Repression of c-myc gene expression by the thiol and disulfide forms of the cytoprotector amifostine
    • Liu, S.C., Murley, J.S., Woloschak, G. & Grdina, D.J. (1997) Repression of c-myc gene expression by the thiol and disulfide forms of the cytoprotector amifostine. Carcinogenesis 18, 2457-2459.
    • (1997) Carcinogenesis , vol.18 , pp. 2457-2459
    • Liu, S.C.1    Murley, J.S.2    Woloschak, G.3    Grdina, D.J.4
  • 19
    • 0031473153 scopus 로고    scopus 로고
    • WR-1065, an active metabolite of the cytoprotector amifostine, affects phosphorylation of topoisomerase II alpha leading to changes in enzyme activity and cell cycle progression in CHO AA8 cells
    • Murley, J.S., Constantinou, A., Kamath, N.S. & Grdina, D.J. (1997) WR-1065, an active metabolite of the cytoprotector amifostine, affects phosphorylation of topoisomerase II alpha leading to changes in enzyme activity and cell cycle progression in CHO AA8 cells. Cell Proliferation 30, 283-294.
    • (1997) Cell Proliferation , vol.30 , pp. 283-294
    • Murley, J.S.1    Constantinou, A.2    Kamath, N.S.3    Grdina, D.J.4
  • 20
    • 0029162994 scopus 로고
    • Amifostine improves the antileukemic therapeutic index of mafosfamide: Implications for bone marrow purging
    • Douay, L., Hu, C., Giarratana, M.C., Bouchet, S., Conlon, J., Capizzi, R.L. & Gorin, N.C. (1995) Amifostine improves the antileukemic therapeutic index of mafosfamide: Implications for bone marrow purging. Blood 86, 2849-2855.
    • (1995) Blood , vol.86 , pp. 2849-2855
    • Douay, L.1    Hu, C.2    Giarratana, M.C.3    Bouchet, S.4    Conlon, J.5    Capizzi, R.L.6    Gorin, N.C.7
  • 21
    • 0020413641 scopus 로고
    • Protection and potentiation of nitrogen mustard cytotoxicity by WR-2721
    • Valeriote, F. & Tolen, S. (1982) Protection and potentiation of nitrogen mustard cytotoxicity by WR-2721. Cancer Res. 42, 4330-4331.
    • (1982) Cancer Res. , vol.42 , pp. 4330-4331
    • Valeriote, F.1    Tolen, S.2
  • 22
    • 0000323921 scopus 로고    scopus 로고
    • The effects of amifostine on the clonogenic proliferation in vitro of myelodysplastic and acute and chronic myelogenous leukemia cells
    • Huang, X.K., Gao, X.Z., Burke, P., Raza, A. & Preisler, H.D. (1997) The effects of amifostine on the clonogenic proliferation in vitro of myelodysplastic and acute and chronic myelogenous leukemia cells. ASCO Proc. 16, 1848a.
    • (1997) ASCO Proc. , vol.16
    • Huang, X.K.1    Gao, X.Z.2    Burke, P.3    Raza, A.4    Preisler, H.D.5
  • 23
    • 0023919963 scopus 로고
    • A simple technique for quantitation of low levels of DNA damage in individual cells
    • Singh, N.P., McCoy, T., Tice, R.R. & Schneider, E.L. (1988) A simple technique for quantitation of low levels of DNA damage in individual cells. Exp. Cell Res. 175, 184-192.
    • (1988) Exp. Cell Res. , vol.175 , pp. 184-192
    • Singh, N.P.1    McCoy, T.2    Tice, R.R.3    Schneider, E.L.4
  • 24
    • 0030580947 scopus 로고    scopus 로고
    • The comet assay: Mechanisms and technical considerations
    • Klaude, M., Eriksson, S., Nygren, J. & Ahnstrom, G. (1996) The comet assay: Mechanisms and technical considerations. Mutat. Res. 12, 89-96.
    • (1996) Mutat. Res. , vol.12 , pp. 89-96
    • Klaude, M.1    Eriksson, S.2    Nygren, J.3    Ahnstrom, G.4
  • 25
    • 0035232156 scopus 로고    scopus 로고
    • Protective action of vitamin C against DNA damage induced by selenium-cisplatin conjugate
    • Błasiak, J. & Kowalik, J. (2001) Protective action of vitamin C against DNA damage induced by selenium-cisplatin conjugate. Acta Biochim. Polon. 48, 233-240.
    • (2001) Acta Biochim. Polon. , vol.48 , pp. 233-240
    • Błasiak, J.1    Kowalik, J.2
  • 26
    • 0028910894 scopus 로고
    • The single cell gel electrophoresis assay for induced DNA damage (comet assay): Measurement of tail lenght and moment
    • Ashby, J.A., Tinwell, H., Lefevre, P.A. & Brown, M.A. (1995) The single cell gel electrophoresis assay for induced DNA damage (comet assay): Measurement of tail lenght and moment. Mutagenesis 10, 85-90.
    • (1995) Mutagenesis , vol.10 , pp. 85-90
    • Ashby, J.A.1    Tinwell, H.2    Lefevre, P.A.3    Brown, M.A.4
  • 27
    • 0031811052 scopus 로고    scopus 로고
    • Chemoprotection in anticancer therapy: The emerging role of amifostine (WR-2721)
    • Kurbacher, C.M. & Mallmann, P.K. (1998) Chemoprotection in anticancer therapy: The emerging role of amifostine (WR-2721). Anticancer Res. 18, 2203-2210.
    • (1998) Anticancer Res. , vol.18 , pp. 2203-2210
    • Kurbacher, C.M.1    Mallmann, P.K.2
  • 28
    • 7344224953 scopus 로고    scopus 로고
    • In vitro effect of amifostine on haematopoietic progenitors exposed to carboplatin and non-alkylating antineoplastic drugs: Haematoprotection acts as a drug-specific progenitor rescue
    • Pierelli, L., Scambia, G., Fattorossi, A., Bonanno, G., Battaglia, A., Perillo, A., Menichella, G., Panici, P.B., Leone, G. & Mancuso, S. (1998) In vitro effect of amifostine on haematopoietic progenitors exposed to carboplatin and non-alkylating antineoplastic drugs: Haematoprotection acts as a drug-specific progenitor rescue. Br. J. Cancer 78, 1024-1029.
    • (1998) Br. J. Cancer , vol.78 , pp. 1024-1029
    • Pierelli, L.1    Scambia, G.2    Fattorossi, A.3    Bonanno, G.4    Battaglia, A.5    Perillo, A.6    Menichella, G.7    Panici, P.B.8    Leone, G.9    Mancuso, S.10
  • 30
    • 0029741151 scopus 로고    scopus 로고
    • Binding of radioprotective thiols and disulfides in Chinese hamster V79 cell nuclei
    • Newton, G.L., Aguilera, J.A., Ward, J.F. & Fahey, R.C. (1996) Binding of radioprotective thiols and disulfides in Chinese hamster V79 cell nuclei. Radiat. Res. 146, 289-305.
    • (1996) Radiat. Res. , vol.146 , pp. 289-305
    • Newton, G.L.1    Aguilera, J.A.2    Ward, J.F.3    Fahey, R.C.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.