Sporadic and familial cerebral amyloid angiopathies

Brain Pathology

Volumn 12, Issue 3, 2002, Pages 343-357

  Revesz, Tamas ^a,b   Holton, Janice L ^a,b   Lashley, Tammaryn ^a,b   Plant, Gordon ^c   Rostagno, Agueda ^d   Ghiso, Jorge ^d   Frangione, Blas ^d  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c NATIONAL HOSPITAL FOR NEUROLOGY AND NEUROSURGERY   (United Kingdom)

^d NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID PROTEIN; GELSOLIN; PREALBUMIN;

AMINO ACID SUBSTITUTION; AMYLOIDOSIS; BRAIN BLOOD VESSEL; BRAIN DISEASE; BRAIN HEMORRHAGE; CENTRAL NERVOUS SYSTEM; CONFERENCE PAPER; FAMILIAL DISEASE; HUMAN; HUMAN CELL; POINT MUTATION; POLYMERIZATION; PRION DISEASE; PROTEIN CONFORMATION; THROMBOCYTE AGGREGATION; VASCULAR AMYLOIDOSIS; ALZHEIMER DISEASE; ANIMAL; BLOOD VESSEL; DEMENTIA; GENETICS; PATHOLOGY; REVIEW;

ALZHEIMER DISEASE; AMYLOIDOSIS; ANIMALS; BLOOD VESSELS; CEREBRAL AMYLOID ANGIOPATHY; CEREBRAL AMYLOID ANGIOPATHY, FAMILIAL; CEREBRAL HEMORRHAGE; DEMENTIA; HUMANS;

EID: 0036019162     PISSN: 10156305     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1750-3639.2002.tb00449.x     Document Type: Conference Paper

References (141)

1. Isolation of six cysteine proteinase inhibitors from human urine. Their physicochemical and enzyme kinetic properties and concentrations in biological fluids
2. Inflammation and Alzheimer's disease
3. Progression of cerebral amyloid angiopathy: Accumulation of amyloid-beta40 in affected vessels
4. Giant cell arteritis in association with cerebral amyloid angiopathy: Immunohistochemical and molecular studies
5. Lack of apolipoprotein E dramatically reduces amyloid beta-peptide deposition
6. Skin deposits in hereditary cystatin C amyloidosis
7. Leptomeningeal amyloid and variant transthyretins
8. Amyloid angiopathy in Alzheimer's disease
9. Hereditary cerebral hemorrhage with amyloidosis-Dutch type (HCHWA-D): I-A review of clinical, radiologic and genetic aspects
10. Neuronal overexpression of mutant amyloid precursor protein results in prominent deposition of cerebrovascular amyloid
11. The length of amyloid-beta in hereditary cerebral hemorrhage with amyloidosis, Dutch type. Implications for the role of amyloid-beta 1-42 in Alzheimer's disease
12. Amyloid fibril in hereditary cerebral hemorrhage with amyloidosis (HCHWA) is related to the gastroentero-pancreatic neuroendocrine protein, gamma trace
13. CAA in transgenic mouse models of Alzheimer's disease
14. Isolation and characterization of amyloid P component from Alzheimer's disease and other types of cerebral amyloidosis
15. A polymorphism in the cystatin C gene is a novel risk factor for late-onset Alzheimer's disease
16. A variant of Alzheimer's disease with spastic paraparesis and unusual plaques due to deletion of exon 9 of presenilin 1
17. Amyloid beta-protein induces its own production in cultured degenerating cerebrovascular smooth muscle cells
18. Cerebral amyloid angiopathy is a pathogenic lesion in Alzheimer's disease due to a novel presenilin 1 mutation
19. Cerebral amyloid angiopathy in the brains of patients with Alzheimer's disease: The CERAD experience, Part XV
20. Cerebral amyloid angiopathy in dementia and old age
21. Genetic association of a cystatin C gene polymorphism with late-onset Alzheimer disease
22. Nonfibrillar beta-amyloid protein is associated with smooth muscle cells of vessel walls in Alzheimer disease
23. Apolipoprotein E and amyloidogenesis
24. Familial cerebral amyloid angiopathy related to stroke and dementia
25. Familial meningocerebrovascular amyloidosis, Hungarian type, with mutant transthyretin (TTR Asp 18Gly)
26. Vascular variant of prion protein cerebral amyloidosis with tau- positive neurofibrillary tangles: The phenotype of the stop codon 145 mutation in PRNP
27. Alzheimer's soluble amyloid beta is a normal component of human urine
28. Gelsolin variant (Asn-187) in familial amyloidosis, Finnish type
29. Systemic amyloid deposits in familial British dementia
30. Amyloid fibrils in hereditary cerebral hemorrhage with amyloidosis of Icelandic type is a variant of gamma-trace basic protein (cystatin C)
31. Familial cerebral amyloid angiopathy (British type) with nonneuritic amyloid plaque-formation may be due to a novel amyloid protein
32. Chromosome 13 dementia syndromes as models of neurodegeneration
33. Unifying features of systemic and cerebral amyloidosis
34. Amyloid angiopathy and granulomatous angiitis of the central nervous system: A case responding to corticosteroid treatment
35. Congophilic angiopathy in the pathogenesis of Alzheimer's degeneration
36. Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein
37. Characterization and chromosomal localization of a cDNA encoding brain amyloid of Alzheimer's disease
38. Novel amyloid precursor protein mutation in an Iowa family with dementia and severe cerebral amyloid angiopathy
39. Amyloid beta protein (A beta) in Alzheimer's disease brain. Biochemical and immunocytochemical analysis with antibodies specific for forms ending at A beta 40 or A beta 42(43)
40. Leukoencephalopathy in diffuse hemorrhagic cerebral amyloid angiopathy
41. Clinical aspects and diagnostic criteria of sporadic CAA-related hemorrhage
42. Apolipoprotein E epsilon 4 and cerebral hemorrhage associated with amyloid angiopathy
43. Association of apolipoprotein E epsilon2 and vasculopathy in cerebral amyloid angiopathy
44. Hereditary cerebral haemorrhage with amyloidosis
45. Amyloid in familial amyloidosis, Finnish type, is antigenically and structurally related to gelsolin
46. Presenile dementia and cerebral haemorrhage linked to a mutation at codon 692 of the beta-amyloid precursor protein gene
47. Regional distribution of amyloid-Bri deposition and its association with neurofibrillary degeneration in familial British dementia
48. Familial Danish dementia: A novel form of cerebral amyloidosis associated with deposition of both amyloid-Dan and amyloid-beta
49. Expression of human apolipoprotein E reduces amyloid-beta deposition in a mouse model of Alzheimer's disease
50. Variant Alzheimer's disease with spastic paraparesis and cotton wool plaques is caused by PS-1 mutations that lead to exceptionally high amyloid-beta concentrations
51. Analysis of heterogeneous A4 peptides in human cerebrospinal fluid and blood by a newly developed sensitive Western blot assay
52. Cerebral amyloid angiopathy: A significant cause of cerebellar as well as lobar cerebral hemorrhage in the elderly
53. Visualization of A beta 42(43) and A beta 40 in senile plaques with end- specific A beta monoclonals: Evidence that an initially deposited species is A beta 42(43)
54. Full-length amyloid-β (1-42(43)) and amino-terminally modified and truncated amyloid-β 42(43) deposit in diffuse plaques
55. The saga of cystatin C gene mutation causing amyloid angiopathy and brain hemorrhage-clinical genetics in Iceland
56. Production and increased detection of amyloid beta protein and amyloidogenic fragments in brain microvessels, meningeal vessels and choroid plexus in Alzheimer's disease
57. The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor
58. Degeneration of vascular muscle cells in cerebral amyloid angiopathy of Alzheimer disease
59. Furin mediates enhanced production of fibrillogenic ABri peptides in familial British dementia
60. Gelsolin-related familial amyloidosis, Finnish type (FAF), and its variants found worldwide
61. Autonomic nervous system and cardiac involvement in familial amyloidosis, Finnish type (FAF)
62. Gelsolin-related spinal and cerebral amyloid angiopathy
63. Congophilic angiopathy and cerebral hemorrhage
64. Candidate gene for the chromosome 1 familial Alzheimer's disease locus
65. Mutation of the Alzheimer's disease amyloid gene in hereditary cerebral hemorrhage, Dutch type
66. Mutation in gelsolin gene in Finnish hereditary amyloidosis
67. Stroke in Icelandic patients with hereditary amyloid angiopathy is related to a mutation in the cystatin C gene, an inhibitor of cysteine proteases
68. Codeposition of cystatin C with amyloid-beta protein in the brain of Alzheimer disease patients
69. Immunohistochemical characterization of the amyloid deposits and quantitation of pertinent cerebrospinal fluid proteins in hereditary cerebral hemorrhage with amyloidosis
70. Amyloid-associated proteins alpha 1-antichymotrypsin and apolipoprotein E promote assembly of Alzheimer betaprotein into filaments
71. Hereditary cerebral hemorrhage with amyloidosis-Dutch type (HCHWA-D): II-A review of histopathological aspects
72. Human blood-brain barrier receptors for Alzheimer's amyloid-beta 1- 40. Asymmetrical binding, endocytosis, and transcytosis at the apical side of brain microvascular endothelial cell monolayer
73. Cerebrovascular accumulation and increased bloodbrain barrier permeability to circulating Alzheimer's amyloid beta peptide in aged squirrel monkey with cerebral amyloid angiopathy
74. The incidence of cerebral amyloid angiopathy in Alzheimer's disease
75. Cerebral amyloid angiopathy: The vascular pathology and complications
76. Preferential deposition of amyloidβ protein (Aβ) in the form Aβ40 in Alzheimer's disease is associated with a gene dosage effect of the apolipoprotein E E4 allele
77. Amyloid angiopathy and variability in amyloid beta deposition is determined by mutation position in presenilin-1-linked Alzheimer's disease
78. Predominant deposition of amyloid beta(42(43)) in plaques in cases of Alzheimer's disease and hereditary cerebral hemorrhage associated with mutations in the amyloid precursor protein gene
79. Gelsolin-related amyloidosis. Identification of the amyloid protein in Finnish hereditary amyloidosis as a fragment of variant gelsolin
80. Amyloid fibril formation in gelsolin-derived amyloidosis. Definition of the amyloidogenic region and evidence of accelerated amyloid formation of mutant Asn-187 and Tyr-187 gelsolin peptides
81. High frequency of apolipoprotein E epsilon 2 allele is specific for patients with cerebral amyloid angiopathy-related haemorrhage
82. ApoE genotype in relation to sporadic and Alzheimer-related CAA
83. Familial British dementia with amyloid angiopathy: Early clinical, neuropsychological and imaging findings
84. Substitutions at codon 22 of Alzheimer's abeta peptide induce diverse conformational changes and apoptotic effects in human cerebral endothelial cells
85. Alzheimer's disease
86. Amyloid beta precursor protein-mRNA is expressed throughout cerebral vessel walls
87. Ultrastructural evidence of early non-fibrillar abeta42 in the capillary basement membrane of patients with hereditary cerebral hemorrhage with amyloidosis, Dutch type
88. High frequency of apolipoprotein E epsilon 2 allele in hemorrhage due to cerebral amyloid angiopathy
89. The 'Arctic' APP mutation (E693G) causes Alzheimer's disease by enhanced Ab protofibril formation
90. Amyloid angiopathy in a Volga German family with Alzheimer's disease and a presenilin-2 mutation (N141I)
91. The molecular pathology of hereditary cystatin C amyloid angiopathy causing brain hemorrhage
92. The apolipoprotein E epsilon 4 allele is associated with increased neuritic plaques and cerebral amyloid angiopathy in Alzheimer's disease and Lewy body variant
93. Cortical angiopathy in Alzheimer's disease: The formation of dystrophic perivascular neurites is related to the exudation of amyloid fibrils from the pathological vessels
94. Transthyretin amyloidosis: A new mutation associated with dementia
95. Amino-terminal deletions enhance aggregation of beta-amyloid peptides in vitro
96. Familial cerebral amyloid angiopathies
97. Familial cerebral amyloid angiopathy with nonneuritic amyloid plaque formation
98. Expression of a normal and variant Alzheimer's beta-protein gene in amyloid of hereditary cerebral hemorrhage, Dutch type: DNA and protein diagnostic assays
99. Apolipoprotein E-epsilon4 alleles in cerebral amyloid angiopathy and cerebrovascular pathology associated with Alzheimer's disease
100. Shattuck lecture. Neurodegenerative diseases and prions
101. β-amyloid-(1-42) is a major component of cerebrovascular amyloid deposits: Implications for the pathology of Alzheimer disease
102. Transthyretin mutations in health and disease
103. Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease
104. Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease
105. Studien zur Pathologie der Hirngefässe II. Die drusige Entartung der Hirnarterien und Capillaren
106. Isolation and quantification of soluble Alzheimer's beta-peptide from biological fluids
107. Clearance of Alzheimer's amyloid-ss(1-40) peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier
108. A pathogenic presenilin1 deletion causes abberrant Abeta 42 production in the absence of congophilic amyloid plaques
109. Apolipoprotein E: High-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease
110. Heredopathia ophthalmo-otoencephalica
111. Cataract, deafness, cerebellar ataxia, psychosis and dementia: A new syndrome
112. A new βPP mutation related to hereditary cerebral hemorrhage
113. N-terminal heterogeneity of parenchymal and cerebrovascular A beta deposits
114. Cerebral amyloid angiopathy in the elderly
115. Prominent cerebral amyloid angiopathy in transgenic mice overexpressing the London mutant of human APP in neurons
116. Hereditary cerebral hemorrhage with amyloidosis in patients of Dutch origin is related to Alzheimer disease
117. Distribution of Aβ-associated proteins in cerebrovascular amyloid of Alzheimer's disease
118. Senile dementia associated with amyloid beta protein angiopathy and tau perivascular pathology but not neuritic plaques in patients homozygous for the APOE-epsilon4 allele
119. A stop-codon mutation in the BRI gene associated with familial British dementia
120. Meningocere-brovascular amyloidosis associated with a novel transthyretin mis-sense mutation at codon 18 (TTRD 18G)
121. A decamer duplication in the 3′ region of the BRI gene originates an amyloid peptide that is associated with dementia in a Danish kindred
122. Cerebral amyloid angiopathy. A critical review
123. Cerebral amyloid angiopathy: Incidence and complications in the aging brain. II. The distribution of amyloid vascular changes
124. Immunohistochemical study of cerebral amyloid angiopathy. III. Widespread Alzheimer A4 peptide in cerebral microvessel walls colocalizes with gamma trace in patients with leukoencephalopathy
125. Neuropathologic features and grading of Alzheimer-related and sporadic CAA
126. Brain parenchymal and microvascular amyloid in Alzheimer's disease
127. Cerebral amyloid angiopathy without and with cerebral hemorrhages: A comparative histological study
128. Cell-type-specific enhancement of amyloidbeta deposition in a novel presenilin-1 mutation (P117L)
129. Cerebral amyloid angiopathy - Amyloid beta accumulates in putative interstitial fluid drainage pathways in Alzheimer's disease
130. Fibril in senile systemic amyloidosis is derived from normal transthyretin
131. Review. David Oppenheimer Memorial Lecture 1995: Some neuropathological aspects of Alzheimer's disease and its relevance to other disciplines
132. A novel Polish presenilin-1 mutation (P117L) is associated with familial Alzheimer's disease and leads to death as early as the age of 28 years
133. Apolipoprotein E: A pathological chaperone protein in patients with cerebral and systemic amyloid
134. A form of familial presenile dementia with spastic paralysis (including the pathological examination of a case)
135. Familial presenile dementia with spastic paralysis
136. Presence of apolipoprotein E on extracellular neurofibrillary tangles and on meningeal blood vessels precedes the Alzheimer beta-amyloid deposition
137. Beta amyloid is focally deposited within the outer basement membrane in the amyloid angiopathy of Alzheimer's disease. An immunoelectron microscopic study
138. A novel missense mutation in the presenilin-1 gene in a familial Alzheimer's disease pedigree with abundant amyloid angiopathy
139. Vascular transport of Alzheimer's amyloid b peptides and apolipoproteins
140. Blood-brain barrier transport of circulating Alzheimer's amyloid beta
141. Glycoprotein 330/megalin: Probable role in receptor-mediated transport of apolipoprotein J alone and in a complex with Alzheimer disease amyloid beta at the blood-brain and blood-cerebrospinal fluid barriers