Cerebrovascular accumulation and increased blood-brain barrier permeability to circulating Alzheimer's amyloid β peptide in aged squirrel monkey with cerebral amyloid angiopathy

Journal of Neurochemistry

Volumn 70, Issue 1, 1998, Pages 210-215

  Mackic, Jasmina B ^a   Weiss, Martin H ^a   Miao, Wesley ^a   Kirkman, Erlinda ^a   Ghiso, Jorge ^c   Calero, Miguel ^c   Bading, James ^b   Frangione, Blas ^c   Zlokovic, Berislav V ^a  

^a CHILDREN S HOSPITAL LOS ANGELES   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Aging; Alzheimer's amyloid ; Blood brain barrier permeability; Cerebrevascular amyloid angiopathy; Cerebrovascular sequestration; Squirrel monkey

Indexed keywords

AMYLOID BETA PROTEIN;

AGING; ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN BLOOD VESSEL; BRAIN METABOLISM; CELL TRANSPORT; CEREBROVASCULAR DISEASE; CONTROLLED STUDY; MICROCIRCULATION; NONHUMAN; PRIORITY JOURNAL; SQUIRREL MONKEY; VASCULAR AMYLOIDOSIS;

ANIMALIA; SAIMIRI; SCIURIDAE;

EID: 0031961832     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1998.70010210.x     Document Type: Article

References (37)

1. Castaño E. M., Prelli F., Soto C., Beavis R., Matsubara E., Shoji M., and Frangione B. (1996) The length of amyloid-beta in hereditary cerebral hemorrhage with amyloidosis. Dutch type. Implications for the role of amyloid-β 1-42 in Alzheimer's disease. J. Biol. Chem. 271, 32185-32191.
2. Citron M., Diehl T. S., Gordon G., Biere A. L., Seubert P., and Selkoe D. J. (1996) Evidence that the 42- and 40-amino acid forms of amyloid β protein are generated from the β-amyloid precursor protein by different protease activities. Proc. Natl. Acad. Sci. USA 93, 13170-13175.
3. Dickson D. W. (1997) The pathogenesis of senile plaques. J. Neuropathol. Exp. Neurol. 56, 321-339.
4. El Khoury J., Hickman S. E., Thomas C. A., Cao L., Silverstein S. C., and Loike J. D. (1996) Scavenger receptor-mediated adhesion of microglia to β-amyloid fibrils. Nature 382, 716-719.
5. Esler W. P., Stimson E. R., Ghilardi J. R., Vinters H. V., Lee J. P., Mantyh P. W., and Maggio J. E. (1995) In vitro growth of Alzheimer's disease β-amyloid plaques displays first-order kinetics. Biochemistry 35, 749-757.
6. Ghersi-Egea J.-F., Gorevic P. D., Ghiso J., Frangione B., Patlak C. S., and Fenstermacher J. D. (1996) Fate of cerebrospinal fluid-borne amyloid β-peptide: rapid clearance into blood and appreciable accumulation by cerebral arteries. J. Neurochem. 67, 880-883.
7. 1-40 labels amyloid deposits in the aged primate brain in vivo. Neuroreport 7, 2607-2611.
8. Ghiso J., Wisniewski T., and Frangione B. (1994) Unifying features of systemic and cerebral amyloidosis. Mol. Neurobiol. 8, 49-64.
9. Gibaldi M. and Perrier D. (1982) Pharmacokinetics. Marcel Dekker. New York.
10. Hammad S. M., Ranganathan S., Loukinova E., Twal W. O., and Argraves W. S. (1997) Interaction of apolipoprotein J-amyloid β-peptide complex with low density lipoprotein receptor-related protein-2/megalin. A mechanism to prevent pathological accumulation of amyloid β-peptide. J. Biol. Chem. 272, 18644-18649.
11. Jarrett J. T. and Lansbury P. T. Jr. (1993) Seeding "one-dimensional crystallization" of amyloid: a pathogenic mechanism in Alzheimer's disease and scrapie? Cell 73, 1055-1058.
12. Levy E., Carman M. D., Fernandez-Madrid I. J., Power M. D., Lieberburg I., van Duinen S. G., Bots G. T. A. M., Luyendijk W., and Frangione B. (1990) Mutation of the Alzheimer's disease amyloid gene in hereditary cerebral hemorrhage, Dutch type. Science 248, 1124-1126.
13. Maness L. M., Banks W. A., Podlisny M. B., Selkoe D. J., and Kastin A. J. (1994) Passage of human amyloid-β protein 1-40 across the murine blood-brain barrier. Life Sci. 55, 1643-1650.
14. Martel C. L., Mackic J. B., McComb J. G., Ghiso J., and Zlokovic B. V. (1996) Blood-brain barrier uptake of the 40 and 42 amino acid sequences of circulating Alzheimer's amyloid β in guinea pigs. Neurosci. Lett. 206, 157-160.
15. Martel C. L., Mackic J. B., Matsubara E., Governale S., Calero M., Miao W., McComb J. G., Frangione B., Ghiso J., and Zlokovic B. V. (1997) Isoform-specific effects of apolipoproteins E2, E3, and E4 on cerebral capillary sequestration and blood-brain barrier transport of circulating Alzheimer's amyloid β. J. Neurochem. 69, 1995-2004.
16. Masters C. L., Simms G., Weinman N. A., Multhaup G., McDonald B. L., and Beyreuther K. (1985) Amyloid plaque core protein in Alzheimer disease and Down syndrome. Proc. Natl. Acad. Sci. USA 82, 4245-4249.
17. Mattson M. P. and Rydel R. E. (1996) Amyloid ox-tox transducers. Nature 382, 674-675.
18. Poduslo J. F., Curran G. L., Haggard J. J., Biere A. L., and Selkoe D. J. (1997) Permeability and residual plasma volume of human. Dutch variant, and rat amyloid β-protein 1-40 at the blood-brain barrier. Neurobiol. Dis. 4, 27-34.
19. Prior R., Durso D., Frank R., Prikulis I., Cleven S., Ihl R., and Pavlakovic G. (1996) Selective binding of soluble Aβ1-40 and Aβ1-42 to a subset of senile plaques. Am. J. Pathol. 148, 1749-1756.
20. 1-40/vector complex. Proc. Natl. Acad. Sci. USA 92, 10227-10231.
21. Seubert P., Vigo-Pelfrey C., Esch F., Lee M., Dovey H., Davis D., Sinha S., Schlossmacher M., Whaley J., Swindlehurst C., McCormack R., Wolfert R., Selkoe D. J., Lieberburg I., and Schenk D. (1992) Isolation and quantification of soluble Alzheimer's β-peptide from biological fluids. Nature 359, 325-327.
22. Shoji M., Golde T., Ghiso J., Cheung T., Estus S., Shafter L., Cai X.-D., McKay D., Tintner R., Frangione B., and Younkin S. (1992) Production of the Alzheimer amyloid β protein by normal proteolytic processing. Science 258, 126-129.
23. Snedecor G. W. and Cochran W. G. (1989) Statistical Methods, pp. 31-33, 89-98. Iowa State University Press, Ames.
24. Soto C. and Frangione B. (1995) Two conformational states of amyloid β-peptide: implications for the pathogenesis of Alzheimer's disease. Neurosci. Lett. 186, 115-118.
25. Suzuki N., Iwatsubo T., Odaka A., Ishibashi Y., Kitada C., and Ihara Y. (1994) High tissue content of soluble beta 1-40 is linked to cerebral amyloid angiopathy. Am. J. Pathol. 145, 452-460.
26. Triguero D., Buciak J., and Pardridge W. M. (1990) Capillary depletion method for quantification of blood-brain barrier transport of circulating peptides and plasma proteins. J. Neurochem. 54, 1882-1888.
27. Vigo-Pelfrey C., Lee D., Keim P., Lieberburg I., and Schenk D. B. (1993) Characterization of β-amyloid peptide from human cerebrospinal fluid. J. Neurochem. 61, 1965-1968.
28. Vinters H. V. (1987) Cerebral amyloid angiopathy. A critical review. Stroke 18, 311-324.
29. Walker L. C., Masters C., Beyreuther K., and Price D. L. (1990) Amyloid in the brains of aged squirrel monkeys. Acta Neuropathol. (Berl.) 80, 381-387.
30. Walker M. and Lev J. (1953) Statistical Inference, pp. 157-158. Holt. Rinehart and Winston, New York.
31. Wisniewski T. and Frangione B. (1992) Apolipoprotein E: a pathologic chaperone protein in patients with cerebral and systemic amyloid. Neurosci. Lett. 135, 235-238.
32. Yan S. D., Chen X., Fu J., Chen M., Zhu H., Roher A., Slattery T., Zhao L., Nagashima M., Morser J., Migheli A., Nawroth P., Ster D., and Schmidt A. M. (1996) RAGE and amyloid-β peptide neurotoxicity in Alzheimer's disease. Nature 382, 685-691.
33. Zlokovic B. V. (1995) Cerebrovascular permeability to peptides: manipulations of transport systems at the blood-brain barrier. Pharm. Res. 12, 1395-1406.
34. Zlokovic B. V. (1997) Can blood-brain barrier play a role in the development of cerebral amyloidosis and Alzheimer's disease pathology? Neurobiol. Dis. 4, 23-26.
35. Zlokovic B. V., Ghiso J., Mackic J. B., McComb J. G., Weiss M. H., and Frangione B. (1993) Blood-brain barrier transport of circulating Alzheimer's amyloid β. Biochein. Biophys. Res. Commun. 197, 1034-1040.
36. Zlokovic B. V., Martel C. L., Matsubara E., McComb J. G., Zheng G., McCluskey R. T., Frangione B., and Ghiso J. (1996) Glycoprotein 330/megalin: probable role in receptor-mediated transport of apolipoprotein J alone and in a complex with Alzheimer disease amyloid β at the blood-brain and blood-cerebrospinal fluid barriers. Proc. Natl. Acad. Sci. USA 93, 2580-2586.
37. Zlokovic B. V., Mackic J. B., Stins M., McComb J. G., Yan S. D., Stern D., Ghiso J., Frangione B., and Kim K. S. (1997) Binding and transport of amyloid-β peptide at the human blood-brain barrier in vitro. Soc. Neurosci. Abstr. 23, 2235.