Molecular Mechanisms of Ceramide-mediated Telomerase Inhibition in the A549 Human Lung Adenocarcinoma Cell Line

Journal of Biological Chemistry

Volumn 276, Issue 35, 2001, Pages 32506-32514

  Ogretmen, Besim ^a,d   Kraveka, Jacqueline M ^a   Schady, Deborah ^a   Usta, Julnar ^c   Hannun, Yusuf A ^a   Obeid, Lina M ^b  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b RALPH H JOHNSON VA MEDICAL CENTER   (United States)

^c AMERICAN UNIVERSITY OF BEIRUT   (Lebanon)

^d MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIA; CELLS; ENZYME INHIBITION; RNA;

CELL LINE;

BIOCHEMISTRY;

CERAMIDE; MESSENGER RNA; MYC PROTEIN; RNA DIRECTED DNA POLYMERASE; SPHINGOMYELIN PHOSPHODIESTERASE; TELOMERASE; TRANSCRIPTION FACTOR; UBIQUITIN; CYCLOHEXIMIDE; DNA BINDING PROTEIN; LUCIFERASE; N CAPROYLSPHINGOSINE; N-CAPROYLSPHINGOSINE;

ARTICLE; E BOX ELEMENT; ENZYME INHIBITION; ENZYME MECHANISM; GEL MOBILITY SHIFT ASSAY; GENE OVEREXPRESSION; GENETIC TRANSFECTION; HALF LIFE TIME; HUMAN; HUMAN CELL; LUNG ADENOCARCINOMA; NORTHERN BLOTTING; PLASMID; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DEGRADATION; PROTEIN PROTEIN INTERACTION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TELOMERIC REPEAT AMPLIFICATION PROTOCOL; TIME; WESTERN BLOTTING; ADENOCARCINOMA; CELL CULTURE; DRUG ANTAGONISM; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; LUNG TUMOR; METABOLISM; ONCOGENE MYC; REPORTER GENE;

BACTERIA (MICROORGANISMS);

ADENOCARCINOMA; CERAMIDES; CYCLOHEXIMIDE; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, MYC; GENES, REPORTER; HALF-LIFE; HUMANS; LUCIFERASES; LUNG NEOPLASMS; PROMOTER REGIONS (GENETICS); PROTO-ONCOGENE PROTEINS C-MYC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TELOMERASE; TRANSCRIPTION, GENETIC; TRANSFECTION; TUMOR CELLS, CULTURED; UBIQUITINS;

EID: 0035980052     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M101350200     Document Type: Article

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