The Selectivity Filter of the Voltage-gated Sodium Channel is Involved in Channel Activation

Journal of Biological Chemistry

Volumn 276, Issue 30, 2001, Pages 27831-27839

  Hilber, Karlheinz ^a   Sandtner, Walter ^a   Kudlacek, Oliver ^a   Glaaser, Ian W ^e   Weisz, Eva ^a   Kyle, John W ^e   French, Robert J ^d   Fozzard, Harry A ^e   Dudley, Samuel C ^b,c   Todt, Hannes ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c ATLANTA VA MEDICAL CENTER   (United States)

^d UNIVERSITY OF CALGARY   (Canada)

^e UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; MUSCLE; SODIUM;

PERMEATION;

BIOCHEMISTRY;

ALANINE; AMINO ACID; ASPARTIC ACID; CONOTOXIN; MU CONOTOXIN GIIIA; SODIUM CHANNEL; UNCLASSIFIED DRUG; VOLTAGE GATED SODIUM CHANNEL; CONOTOXIN G3;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CHANNEL GATING; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DEPOLARIZATION; ELECTRIC POTENTIAL; FILTER; MEMBRANE PERMEABILITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; RAT; SKELETAL MUSCLE; SLOW INWARD CURRENT; 3' UNTRANSLATED REGION; 5' UNTRANSLATED REGION; ANIMAL; BRAIN; CHEMISTRY; ELECTROPHYSIOLOGY; GENETICS; IC 50; KINETICS; METABOLISM; MUTATION; PATCH CLAMP; POINT MUTATION; PROTEIN CONFORMATION; PROTEIN TERTIARY STRUCTURE; SITE DIRECTED MUTAGENESIS; TIME; XENOPUS;

ANIMALIA;

3' UNTRANSLATED REGIONS; 5' UNTRANSLATED REGIONS; ANIMALS; BRAIN; CONOTOXINS; ELECTROPHYSIOLOGY; INHIBITORY CONCENTRATION 50; KINETICS; MUTAGENESIS, SITE-DIRECTED; MUTATION; PATCH-CLAMP TECHNIQUES; POINT MUTATION; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; RATS; SODIUM CHANNELS; TIME FACTORS; XENOPUS;

EID: 0035958956     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M101933200     Document Type: Article

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