Altered ionic selectivity of the sodium channel revealed by cysteine mutations within the pore

Journal of General Physiology

Volumn 109, Issue 4, 1997, Pages 463-475

  Tsushima, Robert G ^a   Li, Ronald A ^a   Backx, Peter H ^a,b  

^a UNIVERSITY OF TORONTO   (Canada)

^b TORONTO GENERAL HOSPITAL   (Canada)

Author keywords

mutagenesis; permeation; skeletal muscle; sulfhydryl modification

Indexed keywords

AMMONIA; CESIUM ION; ION CHANNEL; LITHIUM ION; POTASSIUM ION; SODIUM CHANNEL; SODIUM ION; THIOL DERIVATIVE;

ANIMAL CELL; ARTICLE; CELL MEMBRANE PERMEABILITY; CELL MEMBRANE TRANSPORT; FEMALE; MEMBRANE ELECTROPHYSIOLOGY; MUTAGENESIS; NONHUMAN; OOCYTE; SKELETAL MUSCLE; XENOPUS;

ANIMALS; CATIONS, DIVALENT; CELL MEMBRANE PERMEABILITY; CYSTEINE; ELECTRIC STIMULATION; ELECTROPHYSIOLOGY; FEMALE; HYDROGEN-ION CONCENTRATION; MEMBRANE POTENTIALS; MUSCLE, SKELETAL; MUTAGENESIS, SITE-DIRECTED; MUTATION; OOCYTES; PATCH-CLAMP TECHNIQUES; RATS; SODIUM CHANNELS; SULFHYDRYL COMPOUNDS; XENOPUS LAEVIS;

EID: 0030894992     PISSN: 00221295     EISSN: None     Source Type: Journal    
DOI: 10.1085/jgp.109.4.463     Document Type: Article

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