Dissecting the thrombopoietin receptor: Functional elements of the Mpl cytoplasmic domain

Proceedings of the National Academy of Sciences of the United States of America

Volumn 94, Issue 6, 1997, Pages 2350-2355

  Drachman, Jonathan G ^a   Kaushansky, Kenneth ^a  

^a UNIVERSITY OF WASHINGTON MEDICAL CENTER   (United States)

Author keywords

JAK; signal transduction; STAT; thrombopoietin; tyrosine phosphorylation

Indexed keywords

MEMBRANE RECEPTOR; THROMBOPOIETIN;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL DIFFERENTIATION; CELL MATURATION; CELL PROLIFERATION; GROWTH REGULATION; MEGAKARYOCYTE; MOUSE; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DETERMINATION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ANIMALS; CELL DIFFERENTIATION; CELL DIVISION; CELL LINE; CELL MEMBRANE; CYTOSOL; DNA-BINDING PROTEINS; INTERLEUKIN-3; KINETICS; MICE; MILK PROTEINS; MUTAGENESIS, SITE-DIRECTED; NEOPLASM PROTEINS; PHOSPHORYLATION; POINT MUTATION; POLYMERASE CHAIN REACTION; PROTO-ONCOGENE PROTEINS; RECEPTORS, CYTOKINE; RECEPTORS, THROMBOPOIETIN; RECOMBINANT PROTEINS; STAT5 TRANSCRIPTION FACTOR; THROMBOPOIETIN; TRANS-ACTIVATORS; TRANSFECTION; TYROSINE;

ANIMALIA; MURINAE;

EID: 0030900247     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.94.6.2350     Document Type: Article

References (46)

1. Kaushansky, K., Lok, S., Holly, R. D., Broudy, V. C., Lin, N., et al. (1994) Nature (London) 369, 568-571.
2. Kaushansky, K., Broudy, V., Lin, N., Jorgensen, M., McCarty, J., Fox, N., Zucker-Franklin, D. & Lofton-Day, C. (1995) Proc. Natl. Acad. Sci. USA 92, 3234-3238.
3. Alexander, W. S., Metcalf, D. & Dunn, A. R. (1995) EMBO J. 14, 5569-5578
4. Broudy, V. C., Lin, N. L., Fox, N., Taga, T., Saito, M. & Kaushansky, K. (1996) Blood 88, 2026-2032.
5. Morella, K. K., Bruno, E., Kumaki, S., Lai, C. F., Fu, J., Wang, H. M., Murray, L., Hoffman, R., Timour, M., Bénit, L., Gisselbrecht, S., Zhvans, H., Wojchowski, D. M., Bauman, H. & Gearing, D. P. (1995) Blood 86, 557-571.
6. Vigon, I., Florindo, C., Fichelson, S., Guenet, J. L., Mattei, M. G., Souyri, M., Cosman, D. & Gisselbrecht, S. (1993) Oncogene 8, 2607-2615.
7. Skoda, R. C., Seldin, D. C., Chiang, M. K., Peichel, C. L., Vogt, T. F. & Leder, P. (1993) EMBO J. 12, 2645-2653.
8. Murakami, M., Narazaki, M., Hibi, M., Yawata, H., Yasukawa, K., Hamaguchi, M., Taga, T. & Kishimoto, T. (1991) Proc. Natl. Acad. Sci. USA 88, 11349-11353.
9. Bénit, L., Courtois, G., Charon, M., Varlet, P., Dusanter-Fourt, I. & Gisselbrecht, S. (1994) J. Virol. 68, 5270-5274.
10. Gurney, A. L., Wong, S. C., Henzel, W. J. & De Sauvage, F. J. (1995) Proc. Natl. Acad. Sci. USA 92, 5292-5296.
11. Drachman, J. G., Griffin, J. D. & Kaushansky, K. (1995) J. Biol. Chem. 270, 4979-4982.
12. Dorsch, M., Fan, P. D., Bogenberger, J. & Goff, S. P. (1995) Biochem. Biophys. Res. Commun. 214, 424-431.
13. Pallard, C., Gouilleux, F., B'enit, L., Cocault, L., Souyri, M., Levy, D., Groner, B., Gisselbrecht, S. & Dusanter-Fourt, I. (1995) EMBO J. 14, 2847-2856.
14. Sattler, M., Durstin, M. A., Frank, D. A., Okuda, K., Kaushansky, K., Salgia, R. & Griffin, J. D. (1995) Exp. Hematol. 23, 1040-1048.
15. Ezumi, Y., Takayama, H. & Okuma, M. (1995) FEBS Lett. 374, 48-52.
16. Mu, S. X., Xia, M., Elliot, G., Bogenberger, J., Swift, S., Bennett, L., Lappinga, D. L., Hecht, R., Lee, R. & Saris, C. J. M. (1995) Blood 86, 4532-4543.
17. Miyakawa, Y., Oda, A., Druker, B. J., Miyazaki, H., Handa, M., Ohashi, H. & Ikeda, Y. (1996) Blood 87, 439-447,
18. Miyakawa, Y., Oda, A., Druker, B. J., Kato, T., Miyazaki, H., Handa, M. & Ikeda, Y. (1995) Blood 86, 23-27.
19. Bacon, C. M., Tortolani, P. J., Shimosaka, A., Rees, R. C., Longo, D. L. & O'Shea, J. J. (1995) FEBS Lett. 370, 63-68.
20. Tortolani, P. J., Johnston, J. A., Bacon, C. M., McVicar, D. W., Shimosaka, A., Linnekin, D., Longo, D. L. & O'Shea, J. J. (1995) Blood 85, 3444-3451.
21. Sasaki, K., Odai, H., Hanazono, Y., Ueno, H., Ogawa, S., Langdon, W. Y., Tanaka, T., Miyagawa, K., Mitani, K., Yazaki, Y. & Hirai, H. (1995) Biochem. Biophys. Res. Commun. 216, 338-347.
22. Heim, M. H., Kerr, I. M., Stark, G. R. & Darnell, J. E., Jr. (1995) Science 267, 1347-1349.
23. Songyang, Z., Shoelson, S. E., McGlade, J., Olivier, P., Pawson, T., Bustelo, X. R., Barbacid, M., Sabe, H., Hanafusa, H., Yi, T., Baltimore, D., Ratinofsky, S., Feldman, R. A. & Contley, L. C. (1994) Mol. Cell. Biol. 14, 2777-2785.
24. Stahl, N., Farruggella, T. J., Boulton, T. G., Zhong, Z., Darnell, J. E., Jr., & Yancopoulos, G. D. (1995) Science 267, 1349-1353.
25. Quelle, F. W., Wang, D., Nosaka, T., Thierfelder, W. E., Stravopodis, D., Weinstein, Y. & Ihle, J. N. (1996) Mol. Cell. Biol. 16, 1622-1631.
26. Damen, J. E., Wakao, H., Miyajima, A., Krosl, J., Humphries, R. K., Cutler, R. L. & Krystal, G. (1995) EMBO J. 14, 5557-5568.
27. Chin, H., Nakamura, N., Kamiyama, R., Miyasaka, N., Ihle, J. N. & Miura, O. (1996) Blood 88, 4415-4425.
28. Baumann, H., Gearing, D. & Ziegler, S. F. (1994) J. Biol. Chem. 269, 16297-16304.
29. Fukunaga, R., Ishizaka, I. E. & Nagata, S. (1993) Cell 74, 1079-1087.
30. Hill, R. J., Zozulya, S., Lu, Y.-L., Hollenbach, P. W., Joyce-Shaikh, B., Bogenberger, J. & Gishizky, M. L. (1996) Cell Growth Differ. 7, 1125-1134.
31. Pronk, G. J., deVries-Smits, A. M., Buday, L., Downward, J., Maassen, J. A., Medema, R. H. & Bos, J. L. (1994) Mol. Cell. Biol. 14, 1575-1581.
32. Lioubin, M. N., Algate, P. A., Tsai, S., Carlberg, K., Aebersold, A. & Rohrschneider, L. R. (1996) Genes Dev. 10, 1084-1095.
33. Damen, J. E., Liu, L., Rosten, P., Humphries, R. K., Jefferson, A. B., Majerus, P. W. & Krystal, G. (1996) Proc. Natl. Acad. Sci. USA 93, 1689-1693.
34. Porteu, F., Rouyez, M. C., Cocault, L., Bénit, L., Charon, M., Picard, F., Gisselbrecht, S., Souyri, M. & Dusanter Fourt, I. (1996) Mol. Cell. Biol. 16, 2473-2482.
35. Drachman, J. G., Sabath, D. F., Fox, N. E. & Kaushansky, K. (1997) Blood 89, 483-492.
36. Fun, G., Cunningham, B. C., Fukunaga, R., Nagata, S., Goeddel, D. V. & Wells, J. A. (1992) Science 256, 1677-1680.
37. D'Andrea, A. D., Yoshimura, A., Youssoufian, H., Zon, L. I., Koo, J. W. & Lodish, H. F. (1991) Mol. Cell. Biol. 11, 1980-1987.
38. Klingmuller, U., Lorenz, U., Cantley, L. C., Neel, B. G. & Lodish, H. F. (1995) Cell 80, 729-738.
39. de la Chapelle, A., Traskelin, A. L. & Juvonen, E. (1993) Proc. Natl. Acad. Sci. USA 90, 4495-4499.
40. Laminet, A. A., Apell, G., Conroy, L. & Kavanaugh, W. M. (1996) J. Biol. Chem. 271, 264-269.
41. van der Geer, P., Wiley, S., Gish, G. D., Lai, V. K., Stephens, R., White, M. F., Kaplan, D. & Pawson, T. (1996) Proc. Natl. Acad. Sci. USA 93, 963-968.
42. Pallard, C., Gouilleux, F., Charon, M., Groner, B., Gisselbrecht, S. & Dusanter-Fourt, I. (1995) J. Biol. Chem. 270, 15942-15945.
43. Fujii, H., Nakagawa, Y., Schindler, U., Kawahara, A., Mori, H., Gouilleux, F., Groner, B., Ihle, J. N., Minami, Y., Miyazaki, T. & Taniguchi, T. (1995) Proc. Natl. Acad. Sci. USA 92, 5482-5486.
44. Tian, S.-S., Tapley, P., Sincich, C., Stein, R. B., Rosen, J. & Lamb, P. (1996) Blood 88, 4435-4444.
45. May, P., Gerhartz, C., Heesel, B., Welte, T., Doppler, W., Graeve, L., Horn, F. & Heinrich, P. C. (1996) FEBS Lett. 394, 221-226.
46. Wu, H., Klingmuller, U., Besmer, P. & Lodish, H. F. (1995) Nature (London) 377, 242-246.