A bird's eye view of the glutathione transferase field

Chemico-Biological Interactions

Volumn 138, Issue 1, 2001, Pages 27-42

  Ketterer, Brian ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTATHIONE TRANSFERASE; LIGANDIN; PROTEIN SUBUNIT; THIOREDOXIN;

BIODIVERSITY; CELL PROLIFERATION; CELLULAR DISTRIBUTION; CRYSTALLIZATION; ENZYME MECHANISM; ENZYME STRUCTURE; GENE CONTROL; GENE EXPRESSION; GENETIC POLYMORPHISM; GENETIC TRANSCRIPTION; GENOTOXICITY; GLUTATHIONE METABOLISM; GLYCOSYLATION; HUMAN; INSECT; KNOCKOUT MOUSE; MOLECULAR CLONING; MULTIGENE FAMILY; NEMATODE; NONHUMAN; PROTEIN EXPRESSION; SHORT SURVEY; TRANSCRIPTION REGULATION;

ANIMALS; BACTERIA; CELL DIVISION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLUTATHIONE TRANSFERASE; HUMANS; MOLECULAR WEIGHT; PLANTS; POLYMORPHISM, GENETIC; SUBSTRATE SPECIFICITY;

AVES; INSECTA;

EID: 0035950458     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-2797(01)00277-0     Document Type: Short Survey

References (56)

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2. Evolution of functional diversity as observed through structural studies of glutathione transferases
3. Folding and assembly of glutathione transferases
4. Role of conserved local motifs in folding and stability of hGSTP1-1
5. A conserved "hydrophobic staple motif" plays a crucial role in the refolding of human glutathione transferase P1-1
6. Conformational properties of five peptides encompassing the entire sequence of pGSTP1-1 domain II
7. Probing subunit interactions in glutathione S-transferases using affinity labeling
8. The hydrophobic lock-and-key intersubunit motif of glutathione transferase A1-1: Implications for catalysis, ligandin function and stability
9. The dimeric state of glutathione S-transferases; role of a key residue at the subunit interface in human GSTP1-1
10. Structural and functional response to mutations at the protein-protein interface of mu class glutathione transferase
11. Equilibrium unfolding and enzyme kinetics of chimeric mu class glutathione transferases
12. Structure and folding of glutathione S-transferase A1-1: Structural transition and ligand interaction
13. Coordinated regulation of stress kinases by GSTp
14. Evolutionary strategy for optimisation of GSH binding and catalysis in Alpha, Pi, Mu and Theta glutathione transferases
15. Exit of products from the active site of human glutathione transferase P1-1 is promoted by valine 10
16. Ser11 plays several roles in the catalytic mechanism of rat glutathione transferase T2-2
17. Structure determination of zeta class glutathione transferase from Arabidopsis thaliana
18. Evaluation of possible active site residues in GSTZ1-1
19. Characterisation of the Omega class glutathione transferases
20. The glutathione S-transferases of the human filarial parasite Onchocerca volvulus
21. Structure, mechanism and evolution of thiol transferases
22. Evolution of the mammalian class-mu glutathione transferase gene cluster
23. Interpreting the broad substrate specificities of glutathione S-transferases
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28. Regualtion of GST-P gene transcription: Past present and future
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31. Drosophila melanogaster glutathione transferase conjugating 4-hydroxynonenal
32. Invertebrate glutathione transferases conjugating 4-hydroxy nonenal: CeGST 5.4
33. Amphibian and bacterial glutathione transferases
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35. 5-androstene-3,17-dione catalysed by human glutathione transferase A1-1
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38. A tale of two enzymes: Tetrachlorohydroquinone dehalogenase and maleylacetoacetate isomerase
39. In vivo effect of xenobiotic compounds on the Proteus mirabilis glutathione tranferases B1-1
40. Identification and functional analysis of the glutathione transferase promotor region in Ochrobactrum anthropi
41. Polymorphic GSTs and cancer predisposition
42. Alpha class glutathione transferase polymorphisms identified by EST database analysis
43. Genetic polymorphism of human glutathione transferases
44. Interaction between GSTT1 genotype and smoking on lung cancer risk
45. How important are GST polymorphisms in defining clinical phenotypes: Some answers from studies in high-risk groups
46. Polymorphism at the glutathione S-transferase GSTP1 locus is associated with isocyanate-induced asthma: Use of an ARMS-PCR assay for the simultaneous determination of I105-V105 and A114-V114 alleles
47. Glutathione S-transferase GSTT2 polymorphism and outcome in patients with colorectal cancer
48. Issues and assays for single nucleotide polymorphism analysis in complex disease
49. Functional and genetic analysis of glutathione S-transferase π
50. 2 transcription factor regulates basal expression of class Alpha and Mu glutathione S-transferases in the mouse, but not necessarily their induction by cancer chemopreventive agents
51. The influence of GST-targeted drugs on cell proliferation and stress response
52. Kinetic mechanism of microsomal glutathione transferase 1
53. Oxidative and proteolytic activation of liver microsomal glutathione S-transferase (GSTm) of rats
54. Microsomal glutathione S-transferase 1 activation in relation to the Cytochrome P450 system
55. Molecular analysis of human LTC4 synthase function
56. Prostaglandin E synthase: A microsomal, glutathione dependent, inducible member of the MAPEG superfamily