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Volumn 133, Issue 1-3, 2001, Pages 192-195

Exit of products from the active site of human glutathione transferase P1-1 is promoted by valine 10

Author keywords

Catalytic mechanism; Glutathione transferase; H site; Site directed mutagenesis

Indexed keywords


EID: 0003129127     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (3)

References (10)
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  • 3
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    • Expression of recombinant glutathione S-transferases π Ya or Yb confers resistance to alkylating agents
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  • 5
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    • Three-dimensional structure of class π glutathione S-transferase from human placenta in complex with S-hexylglutathione at 2.8 Å resolution
    • P. Reinemer, H.W. Dirr, R. Ladenstein, R. Huber, M. Lo Bello, G. Federici, M.W. Parker, Three-dimensional structure of class π glutathione S-transferase from human placenta in complex with S-hexylglutathione at 2.8 Å resolution, J. Mol. Biol. 227 (1992) 214-226.
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  • 6
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    • Structures of class pi glutathione S-transferases from human placenta in complex with substrate, transition-state analogue and inhibitor
    • L. Prade, R. Huber, T.H. Manoharan, W.E. Fahl, W. Reuter, Structures of class pi glutathione S-transferases from human placenta in complex with substrate, transition-state analogue and inhibitor, Structure 5 (1997) 1287-1295.
    • (1997) Structure , vol.5 , pp. 1287-1295
    • Prade, L.1    Huber, R.2    Manoharan, T.H.3    Fahl, W.E.4    Reuter, W.5
  • 7
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    • The structures of human glutathione transferase P1-1 in complex with glutathione and various inhibitors at high resolution
    • A.J. Oakley, M. Lo Bello, A. Battistoni, G. Ricci, J. Rossjohn, H.O. Villar, M.W. Parker, The structures of human glutathione transferase P1-1 in complex with glutathione and various inhibitors at high resolution, J. Mol. Biol. 274 (1997) 84-100.
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  • 8
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    • The three-dimensional structure of human pi class glutathione transferase P1-1 in complex with the inhibitor ethacrynic acid and its glutathione conjugate
    • A.J. Oakley, J. Rossjohn, M. Lo Bello, A.M. Caccuri, G. Federici, M.W. Parker, The three-dimensional structure of human pi class glutathione transferase P1-1 in complex with the inhibitor ethacrynic acid and its glutathione conjugate, Biochemistry 36 (1997) 576-585.
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    • Oakley, A.J.1    Rossjohn, J.2    Lo Bello, M.3    Caccuri, A.M.4    Federici, G.5    Parker, M.W.6
  • 9
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    • Structure and function of the xenobiotic substrate-binding site and the location of a potential non-substrate-binding site in a class π glutathione S-transferase
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  • 10
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    • The ligandin (non-substrate) binding site of human pi class glutathione transferase is located in the electrophile binding site (H-site)
    • A.J. Oakley, M. Lo Bello, M. Nuccetelli, A.P. Mazzetti, M.W. Parker, The ligandin (non-substrate) binding site of human pi class glutathione transferase is located in the electrophile binding site (H-site), J. Mol. Biol. 291 (1999) 913-926.
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.