Evolution of functional diversity as observed through structural studies of glutathione transferases

Chemico-Biological Interactions

Volumn 133, Issue 1-3, 2001, Pages 8-12

  Parker, Michael W ^a   McKinstry, William J ^a   Oakley, Aaron J ^a   Polekhina, Galina ^a   Rossjohn, Jamie ^a   Chelvanayagam, Gareth ^b   Board, Philip G ^b   Di Ilio, Carmine ^c   Caccuri, Anna Maria ^d   Ricci, Giorgio ^d   Lo Bello, Mario ^d  

^a ST VINCENT'S INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b Biology and Environment   (Australia)

^c Dipartimento di Scienze Biomediche   (Italy)

^d UNIVERSITY OF ROME TOR VERGATA   (Italy)

Author keywords

Crystallography; Evolution; Glutathione transferase; Structure

Indexed keywords

EID: 0003139175     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (11)

1. P. Reinemer, H.W. Dirr, R. Ladenstein, R. Huber, M. Lo Bello, G. Federici, M.W. Parker, Three-dimensional structure of class pi glutathione S-transferase from human placenta in complex with S-hexylglutathione at 2.8 Å resolution, J. Mol. Biol. 227 (1992) 214-226.
2. A.J. Oakley, J. Rossjohn, M. Lo Bello, A.M. Caccuri, G. Federici, M.W. Parker, The three-dimensional structure of the human pi class glutathione transferase P1-1 in complex with the inhibitor ethacrynic acid and its glutathione conjugate, Biochemistry 36 (1997) 576-585.
3. A.J. Oakley, M. Lo Bello, A. Battistoni, G. Ricci, J. Rossjohn, H.O. Villar, M.W. Parker, The structures of human glutathione transferase P1-1 in complex with glutathione and various inhibitors at high resolution, J. Mol. Biol. 274 (1997) 84-100.
4. A.J. Oakley, M. Lo Bello, A.P. Mazzetti, G. Federici, M.W. Parker, The glutathione conjugate of ethacrynic acid can bind to human pi class glutathione transferase P1-1 in two different modes, FEBS Lett. 419 (1997) 32-36.
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7. J. Rossjohn, G. Polekhina, S.C. Feil, N. Allocati, M. Masulli, C. Di Ilio, M.W. Parker, A mixed disulfide bond in bacterial glutathione transferase: functional and evolutionary implications, Structure 6 (1998) 721-734.
8. J. Rossjohn, W.J. McKinstry, A.J. Oakley, D. Verger, G. Chelvanayagam, K.-L. Tan, J. Flannigan, P.G. Board, M.W. Parker, Human theta class glutathione transferase: the crystal structure reveals a sulfate-binding pocket within a buried active site, Structure 6 (1998) 309-322.
9. R.N. Armstrong, Structure, catalytic mechanism, and evolution of the glutathione transferases, Chem. Res. Toxicol. 10 (1997) 2-18.
10. P. Reinemer, H.W. Dirr, R. Ladenstein, J. Schäffer, O. Gallay, R. Huber, The three-dimensional structure of class pi glutathione S-transferase in complex with glutathione sulfonate at 2.3 Å resolution, EMBO J. 10 (1991) 1997-2005.
11. J. Martin, Thioredoxin - a fold for all reasons, Structure 3 (1995) 245-250.