Expression and localization of inhibin/activin subunits and activin receptors in MCF-7 cells, a human breast cancer cell line

Breast Cancer Research and Treatment

Volumn 37, Issue 2, 1996, Pages 151-160

  Ying, Shao Yao ^a   Zhang, Zhong ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Activin; Activin receptor; Gene expression; Immunocytochemistry; Inhibin; MCF 7

Indexed keywords

ACTIVIN; GROWTH FACTOR; INHIBIN; MESSENGER RNA; PROTEIN SUBUNIT; RECEPTOR; TRANSFORMING GROWTH FACTOR BETA;

ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CELL DIFFERENTIATION; CELL GROWTH; DNA SEQUENCE; GROWTH REGULATION; HORMONE SYNTHESIS; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; IN SITU HYBRIDIZATION; PRIORITY JOURNAL; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ACTIVIN RECEPTORS; ACTIVINS; ADENOCARCINOMA; BASE SEQUENCE; BREAST NEOPLASMS; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; INHIBINS; MOLECULAR SEQUENCE DATA; POLYMERASE CHAIN REACTION; RECEPTORS, GROWTH FACTOR; RNA, MESSENGER; TUMOR CELLS, CULTURED;

EID: 0030071605     PISSN: 01676806     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF01806496     Document Type: Article

References (49)

1. Ying SY: Inhibins, activins, and follistatins: gonadal proteins modulating the secretion of follicle-stimulating hormone. Endo Rev 9: 267-293, 1988
2. Mason AJ, Hayflick JS, Ling N, Esch F, Ueno N, Ying S-Y, Guillemin R, Niall H, Seeburg PH: Ovarian follicular fluid inhibin: Complementary DNA sequences show precursor structure and homology with transforming growth factor-beta. Nature 318: 659-663, 1985
3. Ling N, Ying S-Y, Ueno N, Shimasaki S, Esch F, Hotta M, Guillemin R: Pituitary FSH is released by a heterodimer of the β-subunits from the two forms of inhibin. Nature 321: 779-782, 1986
4. Vale WW, Rivier J, Vaughan J, McClintock R, Corrigan A, Woo W, Karr D, Spiess J: Purification and characterization of an FSH releasing protein from porcine ovarian follicular fluid. Nature 321: 776-779, 1986
5. Ling N, Ying S-Y, Ueno N, Esch F, Denoroy L, Guillemin R: Isolation and partial characterization of a Mr 32,000 protein with inhibin activity from porcine follicular fluid. Proc Natl Acad Sci USA 82: 7217-7221, 1985
6. Mason AJ, Niall HD, Seeburg PH: Structure of two human ovarian inhibins. Biochem Biophys Res Commun 137: 957-964, 1986
7. Derynck R, Jarrett JA, Chen EY, Eaton DH, Bell JR, Assoian RK, Roberts AB, Sporn MB, Goeddel DV: Human transforming growth factor-beta complementary DNA sequence and expression in normal and transformed cells. Nature 316: 701-705, 1985
8. Cate RL, Mattaliano RJ, Hession C, Tizard R, Farber NM, Cheung A, Ninfa EG, Frey NM, Gash DJ, Chow EP, Fisher RA, Bertonis JM, Torres G, Wallner BP, Ramachandran KL, Ragin RC, Manganaro TF, MacLaughlin DT, Donahoe PK: Isolation of the bovine and human genes for Mullerian inhibiting substance and expression of the gene in animal cells. Cell 45: 686-694, 1986
9. Wozney JM, Rosen V, Celeste AJ, Mitsock LM, Whitters MJ, Kriz RW, Hewick RM, Wang EA: Novel regulators of bone formation: molecular clones and activities. Science 242: 1528-1534, 1988
10. Weeks DL, Melton DA: A maternal mRNA localized to the vegetal hemisphere in Xenopus eggs codes for a growth factor related to TGF-β. Cell 51: 861-867, 1987
11. Padgett RW, St Johnston D, Gelbert WM: A transcript from a Drosophila pattern gene predicts a protein homologous to the transforming growth factor-β family. Nature 325: 81-84, 1987
12. Eto Y, Tsiji T, Takegawa M, Takano S, Yakagawa Y, Shibai H: Purification and characterization of erythroid differentiation factor (EDF) isolated from human leukemia cell line THP-1. Biochem Biophys Res Commun 42: 1095-1103, 1987
13. Schubert D, Kimura H, LaCorbiere M, Vaughan J, Karr D, Fischer WH: Activin is a nerve cell survival molecule. Nature 344: 868-870, 1990
14. Scher W, Eto Y, Ejima D, Den T, Svet-Moldavsky IA: Phorbol ester-treated human acute myeloid leukemia cells secrete G-CSF, GM-CSF and erythroid differentiation factor into serum-free media in primary culture. Biochim Biophys Acta 1055: 278-286, 1990
15. Fujimoto K, Kawakita M, Kato K, Yonemura Y, Masuda T, Matsuzaki H, Hirose J, Isaji M, Sasaki H, Inoue T et al.: Purification of megakaryocyte differentiation activity from a human fibrous histiocytoma cell line; N-terminal sequence homology with activin-A, Biochem Biophys Res Commun 174: 1163-1168, 1991
16. Lee W, Mason AJ, Schwall R, Szonyi E, Mather JP: Secretion of activin by interstitial cells in the testis. Science 243: 396-398, 1989
17. Ying SY, Becker A, Ling N, Ueno N, Guillemin R: Inhibin and beta type transforming growth factor (TGFβ) have opposite modulating effects on the follicle stimulating hormone (FSH)-induced aromatase activity of cultured rat granulosa cells. Biochem Biophys Res Commun 136: 969-975, 1986
18. Hutchinson LA, Findlay JR, de Vos FL, Roberlson DM: Effects of bovine inhibin, transforming growth factor β and bovine activin-A on granulosa cell differentiation. Biochem Biophys Res Commun 146: 1405-1412, 1987
19. LaPolt PS, Soto D, Su J-G, Campen CA, Vaughan J, Vale W, Hsueh AJW: Activin stimulation of inhibin secretion and messenger RNA levels in cultured granulosa cells. Mol Endocrinol 3: 1666-1673, 1989
20. Gozalez-Manchon C, Vale W: Activin-A, inhibin and transforming growth factor-β modulate growth of two gonadal cell lines. Endocrinology 125: 1666-1672, 1989
21. Slack J: Embryology. Molecule of the moment [news]. Nature 349: 17-18, 1991
22. Matzuk MM, Finegold MJ, Su J-G, Hsueh AJW, Bradley A: β-inhibin is a tumor-suppressor gene with gonadal specificity in mice. Nature 360: 313-319, 1992
23. Bilous M, Milliken J, Mathijs JM: Immunocytochemistry and in situ hybridisation of epidermal growth factor receptor and relation to prognostic factors in breast cancer. Europ J Cancer 28A: 1033-1037, 1992
24. Peyrat JP, Bonneterre J, Boily B, Demaille A: Basic fibroblast growth factor (bFGF): mitogenic activity and binding sites in human breast cancer. J Steroid Biochem Molec Biol 43: 87-94, 1992
25. Rosen N, Yee D, Lippman ME, Paik S, Cullen KJ: Insulin-like growth factors in human breast cancer. Breast Cancer Res Treat 18 suppl 1: s55-s62, 1991
26. Leung BS, Stout L, Zhou L, Ji HJ, Zhang QQ, Leung HT: Evidence of an EGF/TGFα-independent pathway for estrogen-regulated cell proliferation. J Cell Biochem 46:123-133, 1991
27. Croxtall JD, Jamil A, Aayud M, Colletta AA, White JO: TGFβ stimulation of cndometrial and breast-cancer cell growth. Int J Cancer 50: 822-827, 1992
28. Massague J: Epidermal growth factor-like transforming growth factor. J Biol Chem 258: 13606-13613, 1983
29. Daniel CW, Silberstein GB: Postnatal development of the rodent mammary gland. In: Neville MC, Daniel CW (eds) The Mammary Gland: Development, Regulation, and Function. Plenum Press, New York, pp 3-36, 1987
30. Silberstein GB, Daniel CW: Reversible inhibition of mammary gland growth by transforming growth factor-β. Science 237: 291-293, 1987
31. Daniel CW, Silberstein GB, Van Horn K, Strickland P, Robinson S: TGFβ1-induced inhibition of mouse mammary ductal growth: Development specificity and characterization. Dev Biol 135: 20-30, 1989
32. Robinson SD, Silberstein GB, Roberts AB, Flanders KC, Daniel CW: Regulated expression and growth inhibitory effects of transforming growth factor-β isoforms in mouse mammary gland development. Development 113: 867-878, 1991
33. McCune BK, Mullin BR, Flanders KC, Jaffurs WJ, Mullen LT, Sporn MB: Localization of transforming growth factor-β isotypes in lesions of the human breast. Hum Pathol 23: 13-20, 1991
34. Flanders KC, Thompson NL, Cissel DS, Van Obberghen-Schilling E, Baker CC, Kass ME, Ellingsworth LR, Roberts AB, Sporn MB: Transforming growth factor-β1: Histochemical localization with antibodies to different epitopes. J Cell Biol 108: 653-660, 1989
35. Mizukami Y, Nononiura A, Yamada T, Kurumaya H, Hayashi M, Koyasaki N, Taniya T, Noguchi M, Nakamura S, Matsubara F: Immunohistochemical demonstration of growth factors, TGFα, TGF-β, IGF-1 and neu oncogene product in benign and malignant human breast tissues. Anticancer Res 10: 1115-1126, 1990
36. Travers MT, Barrett-Lee PJ, Berger U, Luqmani YA, Gazet J-C, Powles TJ, Coombes RC: Growth factor expression in normal, benign, and malignant breast tissue. Br Med J 296: 1621-1624, 1988
37. Zajchowski D, Band V, Pauzie N, Tager A, Stampfer M, Sager R: Expression of growth factors and oncogenes in normal and tumor-derived human mammary epithelial cells. Cancer Res 48: 7041-7047, 1988
38. Wakefield LM, Colletta AA, McCune BK, Sporn MB: Roles for transforming growth factors-β in the genesis, prevention, and treatment of breast cancer. Cancer Treatment Res 61: 97-136, 1992
39. Zhang Z, Ying SY: Expression of activins and activin receptors in human retinoblastoma cell line Y-79. IOVS (submitted), 1994
40. Mason AJ, Niall HD, Seeburg PH: Structure of two human ovarian inhibins. Biochem Biophys Res Commun 135: 957-964, 1986
41. Matsuzaki K, Xu J, Wang F et al.: A widely expressed transmembrane serine/threonine kinase that does not bind activin, inhibin, transforming growth factor β, or bone morphogenic factor. J Biol Chem 268: 12719-12723, 1993
42. Donaldson CJ, Mathews LS, Vale WW: Molecule cloning and binding properties of the human type II activin receptor. Biochem Biophys Res Commun 184: 310-316, 1992
43. Hilden K, Tuuri T, Eramaa M, Ritvos O: Expression of type II activin receptor genes during differentiation of human K562 cells and cDNA cloning of the human type II B activin receptor. Blood 83: 2163-2170, 1994
44. Barnard GF, Puder M, Begum NA, Chen LB: PCR product sequencing with [A-33P] and [A-32P]dATP. Biotechniques 16: 572-573, 1994
45. Ying SY, Ling N, Guillemin R: Inhibins and activins. Ann N Y Acad Sci 541: 143-152, 1988
46. Meunier H, Cajander SB, Roberts VJ, River C, Sawchenko PE, Hsueh AJW, Vale W: Rapid changes in the expression of inhibin α, βA-, and βB-subunits in ovarian cell types during the rat estrous cycle. Mol Endocrinol 2: 1352-1363, 1988
47. Roberts AB, Anzano MA, Wakefield LM, Roche NS, Stern DF, Mather JO, Attie KM, Woodruff TK, Rice GC, Phillips DM: Activin stimulates spermatogonial proliferation in germ-cell cocultures from immature rat testis. Endocrinology 127: 3206-3214, 1990
48. 2) mRNA in the rat seminiferous epithelium. Endocrinology 132: 477-479, 1993
49. Shikone T, Matzuk MM, Perlas E, Finegold MJ, Lewis KA, Vale W, Bradley A, Hsueh AJW: Characterization of gonadal sex cord-stromal tumor cell lines from inhibin-α and p53-deficient mice: The role of activin as an autocrine growth factor. Mol Endocr 8: 983-995, 1994