Dominant sensitization variants of human O6-methylguanine-DNA-methyltransferase obtained by a mutational screen of surface residues

Mutation Research - DNA Repair

Volumn 459, Issue 1, 2000, Pages 81-87

  Brown, Lesley R ^a   Deng, Jing ^a   Clarke, Neil D ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cassette mutagenesis; MNNG sensitization; O6 methylguanine DNA methyltransferase

Indexed keywords

METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; METHYLNITRONITROSOGUANIDINE;

ARTICLE; CYTOTOXICITY; DNA REPAIR; ESCHERICHIA COLI; HUMAN; MUTAGENESIS; MUTATION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SENSITIZATION;

AMINO ACID SEQUENCE; CELL LINE; ESCHERICHIA COLI; HUMANS; METHYLNITRONITROSOGUANIDINE; MOLECULAR SEQUENCE DATA; MUTAGENICITY TESTS; MUTATION; O(6)-METHYLGUANINE-DNA METHYLTRANSFERASE; PROTEIN STRUCTURE, TERTIARY;

EID: 0033963693     PISSN: 09218777     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0921-8777(99)00062-2     Document Type: Article

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