Pharmacokinetics and metabolism in rats of 2,4-diamino-6-benzyloxy-5-nitrosopyrimidine, an inactivator of O 6-alkylguanine-dna alkyltransferase

Drug Metabolism and Disposition

Volumn 24, Issue 11, 1996, Pages 1205-1211

  Roy, Sandip K ^a   Moschel, Robert C ^b   Dolan, M Eileen ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 AMINOBENZOTRIAZOLE; 2,4 DIAMINO 6 BENZYLOXY 5 NITROSOPYRIMIDINE; 2,4 DIAMINOPYRIMIDINE DERIVATIVE; 6 O ALKYLGUANINE DNA ALKYLTRANSFERASE INHIBITOR; ALLOPURINOL; CARMUSTINE; DICOUMAROL; DRUG METABOLITE; MENADIONE; NITROSOUREA DERIVATIVE; PYRAZOLE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; CELL FRACTIONATION; CONTROLLED STUDY; DNA REPAIR; DRUG CLEARANCE; DRUG CYTOTOXICITY; DRUG DISTRIBUTION; DRUG HALF LIFE; DRUG METABOLISM; DRUG POTENCY; FEMALE; INTRAARTERIAL DRUG ADMINISTRATION; INTRAPERITONEAL DRUG ADMINISTRATION; INTRATHECAL DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; LIVER CYTOSOL; LIVER HOMOGENATE; LIVER MICROSOME METABOLISM; LIVER MITOCHONDRION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; ENZYME INHIBITORS; FEMALE; HUMANS; MALE; METHYLTRANSFERASES; MICE; O(6)-METHYLGUANINE-DNA METHYLTRANSFERASE; PYRIMIDINES; RATS; RATS, SPRAGUE-DAWLEY; SUBCELLULAR FRACTIONS;

ANIMALIA;

EID: 0030445802     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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