Effect of DNA on the inactivation of O6-alkylguanine-DNA alkyltransferase by 9-substituted O6-benzylguanine derivatives

Biochemical Pharmacology

Volumn 53, Issue 10, 1997, Pages 1559-1564

  Pegg, Anthony E ^a   Chung, Linda ^a   Moschel, Robert C ^b  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Chemotherapy; Chloroethylating agents; Methylating agents; O6 benzylguanine; O6 alkylguanine DNA alkyltransferase

Indexed keywords

6 O ALKYLGUANINE DNA ALKYLTRANSFERASE; 6 O BENZYLGUANINE; ENZYME INHIBITOR;

ARTICLE; DNA METHYLATION; DNA REPAIR; DRUG DNA BINDING; DRUG STRUCTURE; ENZYME INACTIVATION; PRIORITY JOURNAL; PROTEIN STABILITY;

ANIMALS; ANTINEOPLASTIC AGENTS; BINDING, COMPETITIVE; CELL LINE; DNA; ENZYME INHIBITORS; GUANINE; HEMOCYANIN; HUMANS; METHYLTRANSFERASES; O(6)-METHYLGUANINE-DNA METHYLTRANSFERASE; PROTEIN BINDING;

EID: 0030806252     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(97)00060-9     Document Type: Article

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