A general approach to the synthesis of polyamine linked- monoindolylmaleimides, a new series of trypanothione reductase inhibitors

Chemical and Pharmaceutical Bulletin

Volumn 46, Issue 4, 1998, Pages 707-710

  Salmon, Laurence ^a   Landry, Valérie ^a   Melnyk, Oleg ^a   Maes, Louis ^b   Sergheraert, Christian ^a   Davioud Charvet, Elisabeth ^a  

^a CNRS   (France)

^b JANSSEN RESEARCH FOUNDATION   (Belgium)

Author keywords

2 alkylamino 3 (indol 3 yl)maleimide; N alkylmaleimide; Polyamine; Protein kinase C; Trypanosomatid; Trypanothione reductase

Indexed keywords

ENZYME INHIBITOR; MALEIMIDE DERIVATIVE; POLYAMINE DERIVATIVE; TRYPANOTHIONE;

ARTICLE; DRUG SYNTHESIS; ENZYME INHIBITION; NONHUMAN; STRUCTURE ACTIVITY RELATION; TRYPANOSOMA CRUZI; TRYPANOSOMIASIS;

EID: 0031956640     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.46.707     Document Type: Article

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