-
1
-
-
0003867851
-
Strategies in the design and synthesis of chemical libraries
-
Gordon E.M., Kerwin J.F. Jr (Eds.), Combinatorial Chemistry and Molecular Diversity in Drug Discovery
-
(1998)
, pp. 17-38
-
-
Gordon, E.M.1
-
2
-
-
0033683359
-
Linkers and cleavage strategies in solid-phase organic synthesis and combinatorial chemistry
-
(2000)
Chem. Rev.
, vol.100
, pp. 2091-2157
-
-
Guillier, F.1
-
5
-
-
0024239320
-
Methods for drug discovery: development of potent, selective, orally effective cholecystokinin antagonists
-
(1988)
J. Med. Chem.
, vol.31
, pp. 2235-2246
-
-
Evans, B.E.1
-
7
-
-
0033080540
-
y-dimethyladenine: their chemistry, physicochemical properties, and biological activities
-
(1999)
Heterocycles
, vol.51
, pp. 393-454
-
-
Fujii, T.1
-
8
-
-
0034642532
-
Cyclin-dependent kinase inhibitors: useful targets in cell cycle regulation
-
(2000)
J. Med. Chem.
, vol.43
, pp. 1-18
-
-
Sielecki, T.M.1
-
9
-
-
0032563315
-
Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors
-
(1998)
Science
, vol.281
, pp. 533-538
-
-
Gray, N.S.1
-
10
-
-
0033150476
-
Synthesis and application of functionally diverse 2,6,9-trisubstituted purine libraries as CDK inhibitors
-
(1999)
Chem. Biol.
, vol.6
, pp. 361-375
-
-
Chang, Y.T.1
-
13
-
-
0035832060
-
Novel solid-phase preparation of 2,6,9-trisubstituted purines for combinatorial library generation
-
(2001)
Tetrahedron Lett.
, vol.42
, pp. 2771-2773
-
-
Dorff, P.H.1
-
15
-
-
0031013919
-
Facile preparation of 2,6-disubstituted purines using solid-phase chemistry
-
(1997)
J. Org. Chem.
, vol.62
, pp. 201-203
-
-
Nugiel, D.A.1
-
17
-
-
0032569205
-
Stereoselective synthesis of over two million compounds having structural features both reminiscent of natural products and compatible with miniaturized cell-based assays
-
(1998)
J. Am. Chem. Soc.
, vol.120
, pp. 8565-8566
-
-
Tan, D.S.1
-
18
-
-
0032879750
-
Synthesis and preliminary evaluation of a library of polycyclic small molecules for use in chemical genetic assays
-
(1999)
J. Am. Chem. Soc.
, vol.121
, pp. 9073-9087
-
-
Tan, D.S.1
-
19
-
-
0034678033
-
Target-oriented and diversity-oriented organic synthesis in drug discovery
-
(2000)
Science
, vol.287
, pp. 1964-1969
-
-
Schreiber, S.L.1
-
20
-
-
0000058677
-
Strategies for combinatorial organic synthesis: solution and polymer-supported synthesis of 4-thiazolidinones and 4-metathiazanones derived from amino acids
-
(1995)
J. Org. Chem.
, vol.60
, pp. 7328-7333
-
-
Holmes, C.P.1
-
21
-
-
0030064961
-
Solid-supported combinatorial synthesis of structurally diverse β-lactams
-
(1996)
J. Am. Chem. Soc.
, vol.118
, pp. 253-254
-
-
Ruhland, B.1
-
22
-
-
0029042575
-
Combinatorial organic synthesis of highly functionalized pyrrolidines: identification of a potent angiotensin converting enzyme inhibitor from a mercaptoacyl proline library
-
(1995)
J. Am. Chem. Soc.
, vol.117
, pp. 7029-7030
-
-
Murphy, M.M.1
-
23
-
-
0033615680
-
Stereoselective solid-phase synthesis of a triaza tricyclic ring system: a new chemotype for lead discovery
-
(1999)
J. Org. Chem.
, vol.64
, pp. 8342-8349
-
-
Peng, G.1
-
24
-
-
0006738268
-
Postcondensation modifications of Ugi four-component condensation products: 1-isocyanocyclohexene as a convertible isocyanide. Mechanism of conversion, synthesis of diverse structures and demonstration of resin capture
-
(1997)
J. Am. Chem. Soc.
, vol.119
, pp. 7607-7608
-
-
Keating, T.A.1
Armstrong, R.W.2
-
26
-
-
0033582671
-
Polymer bound 3-hydroxy-2-methylidenepropionic acids. A template for multiple core structure libraries
-
(1999)
J. Org. Chem.
, vol.64
, pp. 1362-1365
-
-
Richter, H.1
-
28
-
-
0032518765
-
Solid-phase synthesis of 1-alkyl-2-alkylthio-5-carbamoylbenzimidazoles
-
(1998)
Tetrahedron Lett.
, vol.39
, pp. 201-204
-
-
Lee, J.1
-
32
-
-
0033617212
-
Solid-phase synthesis of 3,4,5-substituted 1,5-benzodiazepin-2-ones
-
(1999)
J. Org. Chem.
, vol.64
, pp. 3060-3065
-
-
Lee, J.1
-
33
-
-
0033515570
-
Solid-phase synthesis of substituted 4-acyl-1,2,3,4-tetrahydroquinoxalin-2-ones
-
(1999)
J. Org. Chem.
, vol.64
, pp. 2555-2557
-
-
Zaragoza, F.1
-
34
-
-
0033515461
-
Solid-phase synthesis of 3,5-disubstituted 2,3-dihydro-1,5-benzothiazepine-4(5H)-ones
-
(1999)
J. Org. Chem.
, vol.64
, pp. 2219-2231
-
-
Schwarz, M.K.1
-
35
-
-
0000482877
-
Necklace-coded polymer-supported combinatorial synthesis of 2-arylaminobenzimidazoles
-
(1999)
J. Comb. Chem.
, vol.1
, pp. 368-370
-
-
Smith, J.M.1
-
36
-
-
0034175574
-
Solid-phase synthesis of branched thiohydantoin benzimidazolinethiones and branched thiohydantoin tetrahydroquinoxalinediones
-
(2000)
Tetrahedron Lett.
, vol.41
, pp. 2283-2287
-
-
Nefzi, A.1
-
38
-
-
0006647793
-
-
Zhang, J. et al. (2001) Solid-phase synthesis of diverse 1,4-benzodiazepin-1,4-diones. American Chemical Society 221st National Meeting, 1-5 April 2001, San Diego, CA, USA (Abstract ORGN 0656)
-
-
-
-
39
-
-
0035908257
-
Solid-phase synthesis of 3,4-dihydro-2(1H)-quinazolines and 3,4-dihydro-1H-quinazolin-2-thiones
-
(2001)
Tetrahedron Lett.
, vol.42
, pp. 4119-4121
-
-
Sun, Q.1
-
40
-
-
0028173391
-
Libraries from libraries': chemical transformation of combinatorial libraries to extend the range and repertoire of chemical diversity
-
(1994)
Proc. Natl. Acad. Sci. U. S. A.
, vol.91
, pp. 11138-11142
-
-
Ostresh, J.M.1
-
41
-
-
0031767227
-
Solid-phase synthesis of trisubstituted bicyclic guanidines via cyclization of reduced N-acylated dipeptides
-
(1998)
J. Org. Chem.
, vol.63
, pp. 8622-8623
-
-
Ostresh, J.M.1
-
42
-
-
0032497397
-
Combinatorial chemistry: from peptides and peptidomimetics to small organic and heterocyclic compounds
-
(1998)
Bioorg. Med. Chem. Lett.
, vol.8
, pp. 2273-2278
-
-
Nafzi, A.1
-
43
-
-
0033534581
-
Parallel solid-phase synthesis of tetrasubstituted diethylenetriamines via selective amide alkylation and exhaustive reduction of N-acylated dipeptides
-
(1999)
Tetrahedron
, vol.55
, pp. 335-344
-
-
Nefzi, A.1
-
44
-
-
0033534581
-
Parallel solid-phase synthesis of tetrasubstituted diethylenetriamines via selective amide alkylation and exhaustive reduction of N-acylated dipeptides
-
(1999)
Tetrahedron
, vol.55
, pp. 335-344
-
-
Nefzi, A.1
-
45
-
-
0031562077
-
Solid-phase synthesis of heterocyclic compounds from linear peptides: cyclic ureas and thioureas
-
(1997)
Tetrahedron Lett.
, vol.38
, pp. 931-934
-
-
Nefzi, A.1
-
46
-
-
0006751567
-
-
Fernandez, M. et al. (2001) Solid-phase synthesis of piperazine derivatives on ACT high-pressure reaction blocks, Ares reactors. American Chemical Society 221st National Meeting, 1-5 April 2001, San Diego, CA, USA (Abstract ORGN 0134)
-
-
-
-
47
-
-
0006723130
-
-
Fernandez, M. et al. (2001) Solid-phase synthesis of piperazinone derivatives based on the Ugi reduction-cyclization strategy. American Chemical Society 221st National Meeting, 1-5 April 2001, San Diego, CA, USA (Abstract ORGN 0657)
-
-
-
-
51
-
-
0000592289
-
String synthesis. A spatially addressable split procedure
-
(2000)
J. Comb. Chem.
, vol.2
, pp. 220-223
-
-
Furka, A.1
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