메뉴 건너뛰기




Volumn 45, Issue 3, 2001, Pages 169-175

QSAR: Hydropathic analysis of inhibitors of the p53-mdm2 interaction

Author keywords

Drug design; HINT; Hydropathic; Molecular modeling; QSAR

Indexed keywords

PROTEIN MDM2; PROTEIN P53;

EID: 0035889627     PISSN: 08873585     EISSN: None     Source Type: Journal    
DOI: 10.1002/prot.1136     Document Type: Article
Times cited : (22)

References (38)
  • 15
    • 0031280019 scopus 로고    scopus 로고
    • A closer view of an oncoprotein-tumor suppressor interaction
    • (1997) Chem Biol , vol.4 , pp. 791-794
    • Shair, M.D.1
  • 16
    • 0028303752 scopus 로고
    • Several hydrophobic amino acids in the p53 amino-terminal domain are required for transcriptional activation, binding to mdm-2 and the adenovirus 5 E1B 55-kD protein
    • (1994) Genes Dev , vol.8 , pp. 1235-1246
    • Lin, J.1    Chen, J.2    Elenbaas, B.3    Levine, A.J.4
  • 21
    • 0034701042 scopus 로고    scopus 로고
    • Computational methodology for estimating changes in free energies of biomolecular association upon mutation. The importance of bound water in dimer-tetramer assembly for beta 37 mutant hemoglobins
    • (2000) Biochemistry , vol.39 , pp. 1622-1633
    • Burnett, J.C.1    Kellogg, G.E.2    Abraham, D.J.3
  • 22
    • 0026080846 scopus 로고
    • Allosteric modifiers of hemoglobin. 2. Crystallographically determined binding sites and hydrophobic binding/interaction analysis of novel hemoglobin oxygen effectors
    • (1991) J Med Chem , vol.34 , pp. 758-767
    • Wireko, F.C.1    Kellogg, G.E.2    Abraham, D.J.3
  • 24
    • 0030037338 scopus 로고    scopus 로고
    • Differences in hydropathic properties of ligand binding at four independent sites in wheat germ agglutinin-oligosaccharide crystal complexes
    • (1996) Protein Sci , vol.5 , pp. 1466-1476
    • Wright, C.S.1    Kellogg, G.E.2
  • 28
    • 0033396104 scopus 로고    scopus 로고
    • A novel hydropathic intermolecular field analysis (HIFA) for the prediction of ligand-receptor binding affinities
    • (1999) Med Chem Res , vol.9 , pp. 535-547
    • Semus, S.F.1
  • 32
    • 0032946731 scopus 로고    scopus 로고
    • Three-dimensional quantitative structure-activity relationship study on cyclic urea derivatives as HIV-1 protease inhibitors: Application of comparative molecular field analysis
    • (1999) J Med Chem , vol.42 , pp. 249-259
    • Debnath, A.K.1
  • 33
    • 0032554868 scopus 로고    scopus 로고
    • Molecular modeling of phenothiazines and related drugs as multidrug resistance modifiers: A comparative molecular field analysis study
    • (1998) J Med Chem , vol.41 , pp. 1815-1826
    • Pajeva, I.1    Wiese, M.2
  • 38
    • 0033568644 scopus 로고    scopus 로고
    • Computational alanine scanning to probe protein-protein interactions: A novel approach to evaluate binding free energies
    • (1999) J Am Chem Soc , vol.121 , pp. 8133-8143
    • Massova, I.1    Kollman, P.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.