Identification and hydropathic characterization of structural features affecting sequence specificity for doxorubicin intercalation into DNA double-stranded polynucleotides

Nucleic Acids Research

Volumn 26, Issue 20, 1998, Pages 4721-4732

  Kellogg, Glen E ^a   Scarsdale, J Neel ^a   Fornari Jr , Frank A ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DOXORUBICIN; POLYNUCLEOTIDE;

ARTICLE; BASE PAIRING; CHROMATOPHORE; COMPUTER MODEL; CONTROLLED STUDY; DNA SEQUENCE; DRUG DESIGN; DRUG DNA BINDING; HYDROGEN BOND; HYDROPHOBICITY; MOLECULAR INTERACTION; MOLECULAR MODEL; PRIORITY JOURNAL;

BASE PAIRING; BINDING SITES; DNA ADDUCTS; DOXORUBICIN; HYDROGEN BONDING; INTERCALATING AGENTS; LIGANDS; MODELS, MOLECULAR; OLIGODEOXYRIBONUCLEOTIDES; SUBSTRATE SPECIFICITY; THERMODYNAMICS;

EID: 0032531740     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/26.20.4721     Document Type: Article

References (38)

1. Weiss, R.B. (1992) Semin. Oncol., 19, 670-686.
2. Henderson, I.C. and Canellos, G.P. (1990) New Engl. J. Med., 302, 78-90.
3. Fornari, F.A., Randolph, J.K., Yalowich, J.C., Ritke, M.K. and Gewirtz, D.A. (1994) Mol. Pharmacol., 45, 649-656.
4. Momparler, R.L., Karon, M., Siegel, S.E. and Avila, F. (1976) Cancer Res., 36, 2891-2895.
5. Tewey, K.M., Rowe, T.C., Yang, L., Halligan, B.D. and Liu, L.F. (1984) Science, 226, 466-468.
6. Schneider, E., Hsiang, Y. and Liu, L.F. (1990) Adv. Pharmacol., 21, 149-183.
7. Sander, M. and Tsieh, T.-S. (1983) J. Biol. Chem., 258, 8421-8428.
8. Bachur, N.F., Yu, F., Johnson, R., Hickey, R., Wu, Y. and Malkas, L. (1992) Mol. Pharmacol., 41, 993-998.
9. George, J.W., Ghate, S., Matson, S.W. and Besterman, J.M. (1992) J. Biol. Chem., 267, 10683-10689.
10. Graves, D.E. and Krugh, T. (1983) Biochemistry, 22, 3941-3947.
11. Cullinane, C., Cutts, S.M., van Rosmalen, A. and Phillips, D.R. (1994), Nucleic Acids Res., 22, 2296-2303.
12. Frederick, C.A., Williams, L.D., Ughetto, G., van der Marel, G., van Boom, J.H., Rich, A. and Wang, A.H.-J. (1990) Biochemistry, 29, 2538-2549.
13. Pullman, B. (1991) Anti-Cancer Drug Des., 7, 95-105.
14. Chen, K.-X., Gresh, N. and Pullman, B. (1986) Nucleic Acids Res., 14, 2251-2267.
15. Chen, K.-X., Gresh, N. and Pullman, B. (1985) J. Biomol. Struct. Dyn., 3, 445-465.
16. Trist, H. and Phillips, D.R. (1989) Nucleic Acids Res., 17, 3673-3688.
17. Chaires, J.B. (1990) Biophys. Chem., 35, 191.
18. Wireko, F.C., Kellogg, G.E. and Abraham, D.J. (1991) J. Med. Chem., 34, 758-767.
19. Kellogg, G.E., Semus, S.F. and Abraham, D.J. (1991) J. Comput. Aided Mol. Design, 5, 545-552.
20. Kellogg, G.E., Joshi, G.S. and Abraham, D.J. (1992) Med. Chem. Res., 1, 444-453.
21. Abraham, D.J., Kellogg, G.E., Holt, J.M. and Ackers, G.K. (1997) J. Mol. Biol., 272, 613-632.
22. Gussio, R., Pattabiraman, N., Zaharevitz, D.W., Kellogg, G.E., Topol, I.A., Rice, W.G., Schaeffer, C.A., Erickson, J.W. and Burt, S.K. (1996) J. Med. Chem., 39, 1645-1650.
23. Bernstein, F.C., Koetzle, T.F., Williams, G.J.B., Meyer, E.F., Brice, M.D., Rodgers, J.R., Kennard, O., Shimanouchi, T. and Tasumi, M. (1977) J. Mol. Biol., 112, 535-542.
24. Ornstein, R.L. and Rein, R. (1979) Biopolymers, 18, 1277-1291.
25. Goodford, P.J. (1985) J. Med. Chem., 28, 857-864.
26. Chaires, J.B., Satyanarayana, S., Suh, D., Fokt, I., Przewloka, T. and Priebe, W. (1996) Biochemistry, 35, 2047-2053.
27. Hansch, C. and Leo, A.J. (1979) Substituent Constants for Correlation Analysis in Chemistry and Biology. John Wiley & Sons, New York, NY.
28. Abraham, D.J. and Leo, A.J. (1987) Proteins Struct. Funct. Genet., 2, 130-152.
29. Levitt, M. (1983) J. Mol. Biol., 168, 595-620.
30. Levitt, M. and Perutz, M.F. (1988) J. Mol. Biol., 201, 751-754.
31. Huheey, J.E. (1978) Inorganic Chemistry: Principles of Structure and Reactivity. Harper and Row, New York, NY.
32. Wright, C.S. and Kellogg, G.E. (1996) Protein Sci., 5, 1466-1476.
33. Perutz, M..F, Fermi, G., Abraham, D.J., Poyart, C. and Bursaux, E. (1986) J. Am. Chem. Soc., 108, 1064.
34. Burley, S.K. and Petsko, G.A. (1986) FEBS Lett., 201, 751.
35. Chaires, J.B., Herrera, J.E. and Waring, M.J. (1990) Biochemistry, 29, 6145-6153.
36. Skorobogaty, A., White, R.J., Phillips, D.R. and Reiss, J.A. (1988) FEBS Lett., 227, 103-106.
37. Skorobogaty, A., White, R.J., Phillips, D.R. and Reiss, J.A. (1988) Drug Des. Del., 3, 125-151.
38. Li, L. and Yu, F.-H. (1993) Biochem. Mol. Biol. Int., 31, 879-887.