Nedd4 Regulates Ubiquitination and Stability of the Guanine-Nucleotide Exchange Factor CNrasGEF

Journal of Biological Chemistry

Volumn 276, Issue 50, 2001, Pages 46995-47003

  Pham, Nam ^b   Rotin, Daniela ^a  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; DEGRADATION; PROTEINS; SUBSTRATES;

MUTATION;

BIOCHEMISTRY;

8 BROMO CYCLIC AMP; CELL PROTEIN; CYCLIC AMP; CYCLIC AMP DERIVATIVE; CYCLIC NUCLEOTIDE RAS GEF; GUANINE NUCLEOTIDE EXCHANGE FACTOR; LACTACYSTIN; PROTEASOME; PROTEIN TYROSINE PHOSPHATASE; RAP PROTEIN; RAS PROTEIN; UBIQUITIN PROTEIN LIGASE; UBIQUITIN PROTEIN LIGASE NEDD4; UNCLASSIFIED DRUG; 8 BROMO CYCLIC ADENOSINE MONOPHOSPHATE; ACETYLCYSTEINE; CALCIUM BINDING PROTEIN; CALCIUM BINDING PROTEINS; CYCLIC NUCLEOTIDE; CYSTEINE PROTEINASE; DRUG DERIVATIVE; GLUTATHIONE TRANSFERASE; HYBRID PROTEIN; LIGASE; MULTIENZYME COMPLEX; PDZ GEF1 PROTEIN; PDZ-GEF1 PROTEIN; RNEDD4 PROTEIN; UBIQUITIN;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENZYME SUBSTRATE; GENE DELETION; GENE MUTATION; GENE OVEREXPRESSION; HALF LIFE TIME; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MEMBRANE STABILIZATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEIN ISOLATION; PROTEIN MOTIF; PROTEIN STABILITY; PY MOTIF; AMINO ACID SEQUENCE; CATALYSIS; CELL LINE; CHEMISTRY; ENZYME ACTIVATION; GENETIC TRANSFECTION; METABOLISM; MOLECULAR GENETICS; MUTATION; PHYSIOLOGY; PLASMID; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN TERTIARY STRUCTURE; SEQUENCE HOMOLOGY; SERODIAGNOSIS; TIME;

8-BROMO CYCLIC ADENOSINE MONOPHOSPHATE; ACETYLCYSTEINE; AMINO ACID MOTIFS; AMINO ACID SEQUENCE; CALCIUM-BINDING PROTEINS; CATALYSIS; CELL LINE; CYCLIC AMP; CYSTEINE ENDOPEPTIDASES; ENZYME ACTIVATION; GENE DELETION; GLUTATHIONE TRANSFERASE; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HUMAN; LIGASES; MOLECULAR SEQUENCE DATA; MULTIENZYME COMPLEXES; MUTATION; NUCLEOTIDES, CYCLIC; PLASMIDS; PRECIPITIN TESTS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; RAS GUANINE NUCLEOTIDE EXCHANGE FACTORS; RAS PROTEINS; RECOMBINANT FUSION PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SUPPORT, NON-U.S. GOV'T; TIME FACTORS; TRANSFECTION; UBIQUITIN;

EID: 0035861640     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M108373200     Document Type: Article

References (34)

1. Kumar, S., Tomooka, Y., and Noda, M. (1992) Biochem. Biophys. Res. Commun. 185, 1155-1161
2. Staub, O., Dho, S., Henry, P., Correa, J., Ishikawa, T., McGlade, J., and Rotin, D. (1996) EMBO J. 15, 2371-2380
3. Abriel, H., Loffing, J., Rebhun, J. F., Pratt, J. H., Schild, L., Horisberger, J. D., Rotin, D., and Staub, O. (1999) J. Clin. Invest. 103, 667-673
4. Kanelis, V., Rotin, D., and Forman-Kay, J. D. (2001) Nat. Struct. Biol. 8, 407-412
5. Jolliffe, C. N., Harvey, K. F., Haines, B. P., Parasivam, G., and Kumar, S. (2000) Biochem. J. 351, 557-565
6. Pham, N., Cheglakov, I., Koch, C. A., de Hoog, C. L., Moran, M. F., and Rotin, D. (2000) Curr. Biol. 10, 555-558
7. Ohtsuka, T., Hata, Y., Ide, N., Yasuda, T., Inoue, E., Inoue, T., Mizoguchi, A., and Takai, Y. (1999) Biochem. Biophys. Res. Commun. 265, 38-44
8. de Rooij, J., Boenink, N. M., van Triest, M., Cool, R. H., Wittinghofer, A., and Bos, J. L. (1999) J. Biol. Chem. 274, 38125-38130
9. Liao, Y., Kariya, K., Hu, C. D., Shibatohge, M., Goshima, M., Okada, T., Watari, Y., Gao, X., Jin, T. G., Yamawaki-Kataoka, Y., and Kataoka, T. (1999) J. Biol. Chem. 274, 37815-37820
10. Reuther, G. W., and Der, C. J. (2000) Curr. Opin. Cell Biol. 12, 157-165
11. Bar-Sagi, D., and Hall, A. (2000) Cell 103, 227-238
12. Ayllon, V., and Rebollo, A. (2000) Mol. Membr. Biol. 17, 65-73
13. Bos, J. L. (1998) EMBO J. 17, 6776-6782
14. Treier, M., Staszewski, L. M., and Bohmann, D. (1994) Cell 78, 787-798
15. Taylor, S. J., and Shalloway, D. (1996) Curr. Biol. 6, 1621-1627
16. de Rooij, J., and Bos, J. L. (1997) Oncogene 14, 623-625
17. Rotin, D., Staub, O., and Haguenauer-Tsapis, R. (2000) J. Membr. Biol. 176, 1-17
18. Huibregtse, J. M., Yang, J. C., and Beaudenon, S. L. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 3656-3661
19. Kaplon, T., and Jacquet, M. (1995) J. Biol. Chem. 270, 20742-20747
20. Nielsen, K. H., Papageorge, A. G., Vass, W. C., Willumsen, B. M., and Lowy, D. R. (1997) Mol. Cell. Biol. 17, 7132-7138
21. de Hoog, C. L., Koehler, J. A., Goldstein, M. D., Taylor, P., Figeys, D., and Moran, M. F. (2001) Mol. Cell. Biol. 21, 2107-2117
22. Schild, L., Lu, Y., Gautschi, I., Schneeberger, E., Lifton, R. P., and Rossier, B. C. (1996) EMBO J. 15, 2381-2387
23. Bonny, O., and Hummler, E. (2000) Kidney Int. 57, 1313-1318
24. Firsov, D., Schild, L., Gautschi, I., Merillat, A. M., Schneeberger, E., and Rossier, B. C. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 15370-15375
25. Goulet, C. C., Volk, K. A., Adams, C. M., Prince, L. S., Stokes, J. B., and Snyder, P. M. (1998) J. Biol. Chem. 273, 30012-30017
26. Staub, O., Gautschi, I., Ishikawa, T., Breitschopf, K., Ciechanover, A., Schild, L., and Rotin, D. (1997) EMBO J. 16, 6325-6336
27. Shimkets, R. A., Lifton, R. P., and Canessa, C. M. (1997) J. Biol. Chem. 272, 25537-25541
28. Mastroberardino, L., Spindler, B., Forster, I., Loffing, J., Assandri, R., May, A., and Verrey, F. (1998) Mol. Biol. Cell 9, 3417-3427
29. Garty, H., and Palmer, L. G. (1997) Physiol. Rev. 77, 359-396
30. Abriel, H., Kamynina, E., Horisberger, J. D., and Staub, O. (2000) FEBS Lett. 466, 377-380
31. Schwake, M., Friedrich, T., and Jentsch, T. J. (2001) J. Biol. Chem. 276, 12049-12054
32. Hicke, L. (1997) FASEB J. 11, 1215-1226
33. Zhu, H., Kavsak, P., Abdollah, S., Wrana, J. L., and Thomsen, G. H. (1999) Nature 400, 687-693
34. Kavsak, P., Rasmussen, R. K., Causing, C. G., Bonni, S., Zhu, H., Thomsen, G. H., and Wrana, J. L. (2000) Mol. Cell 6, 1365-1375