-
1
-
-
0027474508
-
Mutational analysis of the cAMP-dependent protein kinase-mediated phosphorylation site of Rap1b
-
Altschuler, D. and Lapetina, E.G. (1993) Mutational analysis of the cAMP-dependent protein kinase-mediated phosphorylation site of Rap1b. J. Biol. Chem., 268, 7527-7531.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 7527-7531
-
-
Altschuler, D.1
Lapetina, E.G.2
-
2
-
-
0032560506
-
Mitogenic and oncogenic properties of the small G protein Rap1b
-
Altschuler, D.L. and Ribeiro-Neto, F. (1998) Mitogenic and oncogenic properties of the small G protein Rap1b. Proc. Natl Acad. Sci. USA, 95, 7475-7479.
-
(1998)
Proc. Natl Acad. Sci. USA
, vol.95
, pp. 7475-7479
-
-
Altschuler, D.L.1
Ribeiro-Neto, F.2
-
3
-
-
0028924533
-
Cyclic AMP-dependent activation of Rap1b
-
Altschuler, D.L., Peterson, S.N., Ostrowski, M.C. and Lapetina, E.G. (1995) Cyclic AMP-dependent activation of Rap1b. J. Biol. Chem., 270, 10373-10376.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 10373-10376
-
-
Altschuler, D.L.1
Peterson, S.N.2
Ostrowski, M.C.3
Lapetina, E.G.4
-
4
-
-
0027490707
-
Genetic evidence for the roles of the bud-site-selection genes BUD5 and BUD2 in control of the Rsr1p (Bud1p) GTPase in yeast
-
Bender, A. (1993) Genetic evidence for the roles of the bud-site-selection genes BUD5 and BUD2 in control of the Rsr1p (Bud1p) GTPase in yeast. Proc. Natl Acad. Sci. USA, 90, 9926-9929.
-
(1993)
Proc. Natl Acad. Sci. USA
, vol.90
, pp. 9926-9929
-
-
Bender, A.1
-
5
-
-
0032560850
-
The structural basis of the activation of Ras by Sos
-
Boriack-Sjodin, P.A., Margarit, S.M., Bar-Sagi, D. and Kuriyan, J. (1998) The structural basis of the activation of Ras by Sos. Nature, 394, 337-343.
-
(1998)
Nature
, vol.394
, pp. 337-343
-
-
Boriack-Sjodin, P.A.1
Margarit, S.M.2
Bar-Sagi, D.3
Kuriyan, J.4
-
6
-
-
0024376173
-
ras oncogenes in human cancer: A review
-
Bos, J.L. (1989) ras oncogenes in human cancer: a review. Cancer Res., 49, 4682-4689.
-
(1989)
Cancer Res.
, vol.49
, pp. 4682-4689
-
-
Bos, J.L.1
-
8
-
-
0030848095
-
In search of a function for the Ras-like GTPase Rap1
-
Bos, J.L., Franke, B., M'Rabet, L., Reedquist, K. and Zwartkruis, F. (1997) In search of a function for the Ras-like GTPase Rap1. FEBS Lett., 410, 59-62.
-
(1997)
FEBS Lett.
, vol.410
, pp. 59-62
-
-
Bos, J.L.1
Franke, B.2
M'Rabet, L.3
Reedquist, K.4
Zwartkruis, F.5
-
9
-
-
0030812812
-
Maintenance of human T cell anergy: Blocking of IL-2 gene transcription by activated Rap1
-
Boussiotis, V.A., Freeman, G.J., Berezovskaya, A., Barber, D.L. and Nadler, L.M. (1997) Maintenance of human T cell anergy: blocking of IL-2 gene transcription by activated Rap1. Science, 278, 124-128.
-
(1997)
Science
, vol.278
, pp. 124-128
-
-
Boussiotis, V.A.1
Freeman, G.J.2
Berezovskaya, A.3
Barber, D.L.4
Nadler, L.M.5
-
10
-
-
0028917954
-
Regulation of ras-mediated signalling: More than one way to skin a cat
-
Burgering, B.M.T. and Bos, J.L. (1995) Regulation of ras-mediated signalling: more than one way to skin a cat. Trends. Biochem. Sci., 20, 18-22.
-
(1995)
Trends. Biochem. Sci.
, vol.20
, pp. 18-22
-
-
Burgering, B.M.T.1
Bos, J.L.2
-
11
-
-
0025899140
-
Yeast BUD5, encoding a putative GDP-GTP exchange factor, is necessary for bud site selection and interacts with bud formation gene BEM1
-
Chant, J., Corrado, K., Pringle, J.R. and Herskowitz, I. (1991) Yeast BUD5, encoding a putative GDP-GTP exchange factor, is necessary for bud site selection and interacts with bud formation gene BEM1. Cell, 65, 1213-1224.
-
(1991)
Cell
, vol.65
, pp. 1213-1224
-
-
Chant, J.1
Corrado, K.2
Pringle, J.R.3
Herskowitz, I.4
-
12
-
-
0026586631
-
A yeast gene (BEM1) necessary for cell polarization whose product contains two SH3 domains
-
Chenevert, J., Corrado, K., Bender, A., Pringle, J. and Herskowitz, I. (1992) A yeast gene (BEM1) necessary for cell polarization whose product contains two SH3 domains. Nature, 356, 77-79.
-
(1992)
Nature
, vol.356
, pp. 77-79
-
-
Chenevert, J.1
Corrado, K.2
Bender, A.3
Pringle, J.4
Herskowitz, I.5
-
13
-
-
0027170176
-
RapV12 antagonizes Ras-dependent activation of ERK1 and ERK2 by LPA and EGF in Rat-1 fibroblasts
-
Cook, S.J., Rubinfeld, B., Albert, I. and McCormick, F. (1993) RapV12 antagonizes Ras-dependent activation of ERK1 and ERK2 by LPA and EGF in Rat-1 fibroblasts. EMBO J., 12, 3475-3485.
-
(1993)
EMBO J.
, vol.12
, pp. 3475-3485
-
-
Cook, S.J.1
Rubinfeld, B.2
Albert, I.3
McCormick, F.4
-
14
-
-
0030950471
-
rsc: A novel oncogene with structural and functional homology with the gene family of exchange factors for Ral
-
D'Adamo, D.R., Novick, S., Kahn, J.M., Leonardi, P. and Pellicer, A. (1997) rsc: a novel oncogene with structural and functional homology with the gene family of exchange factors for Ral. Oncogene, 14, 1295-1305.
-
(1997)
Oncogene
, vol.14
, pp. 1295-1305
-
-
D'Adamo, D.R.1
Novick, S.2
Kahn, J.M.3
Leonardi, P.4
Pellicer, A.5
-
15
-
-
0030683639
-
Signal characteristics of G protein-transactivated EGF receptor
-
Daub, H., Wallasch, C., Lankenau, A., Herrlich, A. and Ullrich, A. (1997) Signal characteristics of G protein-transactivated EGF receptor. EMBO J., 16, 7032-7044.
-
(1997)
EMBO J.
, vol.16
, pp. 7032-7044
-
-
Daub, H.1
Wallasch, C.2
Lankenau, A.3
Herrlich, A.4
Ullrich, A.5
-
16
-
-
0032524389
-
RasGRP, a Ras guanyl nucleotide-releasing protein with calcium- and diacylglycerol-binding motifs
-
Ebinu, J.O., Bottorff, D.A., Chan, E.Y., Stang, S.L., Dunn, R.J. and Stone, J.C. (1998) RasGRP, a Ras guanyl nucleotide-releasing protein with calcium- and diacylglycerol-binding motifs. Science, 280, 1082-1086.
-
(1998)
Science
, vol.280
, pp. 1082-1086
-
-
Ebinu, J.O.1
Bottorff, D.A.2
Chan, E.Y.3
Stang, S.L.4
Dunn, R.J.5
Stone, J.C.6
-
17
-
-
0031026133
-
Cloning and characterization of Ras-GRF2, a novel guanine nucleotide exchange factor for Ras
-
Fam, N.P., Fan, W.T., Wang, Z., Zhang, L.J., Chen, H. and Moran, M.F. (1997) Cloning and characterization of Ras-GRF2, a novel guanine nucleotide exchange factor for Ras. Mol. Cell. Biol., 17, 1396-1406.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 1396-1406
-
-
Fam, N.P.1
Fan, W.T.2
Wang, Z.3
Zhang, L.J.4
Chen, H.5
Moran, M.F.6
-
18
-
-
0029098537
-
Calcium activation of Ras mediated by neuronal exchange factor Ras-GRF
-
Farnsworth, C.L., Freshney, N.W., Rosen, L.B., Ghosh, A., Greenberg, M.E. and Feig, L.A. (1995) Calcium activation of Ras mediated by neuronal exchange factor Ras-GRF. Nature, 376, 524-527.
-
(1995)
Nature
, vol.376
, pp. 524-527
-
-
Farnsworth, C.L.1
Freshney, N.W.2
Rosen, L.B.3
Ghosh, A.4
Greenberg, M.E.5
Feig, L.A.6
-
19
-
-
0030296550
-
Evidence for a Ras/Ral signaling cascade
-
Feig, L.A., Urano, T. and Cantor, S. (1996) Evidence for a Ras/Ral signaling cascade. Trends Biochem. Sci., 21, 438-441.
-
(1996)
Trends Biochem. Sci.
, vol.21
, pp. 438-441
-
-
Feig, L.A.1
Urano, T.2
Cantor, S.3
-
22
-
-
0028881018
-
Identification of Rap1 as a target for the Crk SH3 domain-binding guanine nucleotide-releasing factor C3G
-
Gotoh, T. et al. (1995) Identification of Rap1 as a target for the Crk SH3 domain-binding guanine nucleotide-releasing factor C3G. Mol. Cell. Biol., 15, 6746-6753.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 6746-6753
-
-
Gotoh, T.1
-
23
-
-
0025932448
-
The Drosophila roughened mutation: Activation of a rap homolog disrupts eye development and interferes with cell determination
-
Hariharan, I.K., Carthew, R.W. and Rubin, G.M. (1991) The Drosophila roughened mutation: activation of a rap homolog disrupts eye development and interferes with cell determination. Cell, 67, 717-722.
-
(1991)
Cell
, vol.67
, pp. 717-722
-
-
Hariharan, I.K.1
Carthew, R.W.2
Rubin, G.M.3
-
24
-
-
0028153277
-
Activated Ras interacts with the Ral guanine nucleotide dissociation stimulator
-
Hofer, F., Fields, S., Schneider, C. and Martin, G.S. (1994) Activated Ras interacts with the Ral guanine nucleotide dissociation stimulator. Proc. Natl Acad. Sci. USA, 91, 11089-11093.
-
(1994)
Proc. Natl Acad. Sci. USA
, vol.91
, pp. 11089-11093
-
-
Hofer, F.1
Fields, S.2
Schneider, C.3
Martin, G.S.4
-
26
-
-
0030771490
-
Enhancement of guanine-nucleotide exchange activity of C3G for Rap1 by the expression of Crk, CrkL and Grb2
-
Ichiba, T., Kuraishi, Y., Sakai, O., Nagata, S., Groffen, J., Kurata, T. Hattori, S. and Matsuda, M. (1997) Enhancement of guanine-nucleotide exchange activity of C3G for Rap1 by the expression of Crk, CrkL and Grb2. J. Biol. Chem., 272, 22215-22220.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 22215-22220
-
-
Ichiba, T.1
Kuraishi, Y.2
Sakai, O.3
Nagata, S.4
Groffen, J.5
Kurata, T.6
Hattori, S.7
Matsuda, M.8
-
27
-
-
0031974491
-
Identification and characterization of a novel protein interacting with Ral-binding protein 1, a putative effector protein of Ral
-
Ikeda, M., Ishida, O., Hinoi, T. Kishida, S. and Kikuchi, A. (1998) Identification and characterization of a novel protein interacting with Ral-binding protein 1, a putative effector protein of Ral. J. Biol. Chem., 273, 814-821.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 814-821
-
-
Ikeda, M.1
Ishida, O.2
Hinoi, T.3
Kishida, S.4
Kikuchi, A.5
-
28
-
-
0028818914
-
Involvement of Ral GTPase in v-Src-induced phospholipase D activation
-
Jiang, H., Luo, J.Q., Urano, T., Frankel, P., Lu, Z., Foster, D.A. and Feig, L.A. (1995) Involvement of Ral GTPase in v-Src-induced phospholipase D activation. Nature, 378, 409-112.
-
(1995)
Nature
, vol.378
, pp. 409-1112
-
-
Jiang, H.1
Luo, J.Q.2
Urano, T.3
Frankel, P.4
Lu, Z.5
Foster, D.A.6
Feig, L.A.7
-
29
-
-
0345135149
-
K-ras is an essential gene in the mouse with partial functional overlap with N-ras
-
Johnson, L. et al. (1997) K-ras is an essential gene in the mouse with partial functional overlap with N-ras. Genes Dev., 11, 2468-2481.
-
(1997)
Genes Dev.
, vol.11
, pp. 2468-2481
-
-
Johnson, L.1
-
30
-
-
0031043776
-
Signal transduction from multiple Ras effectors
-
Katz, M.E. and McCormick, F. (1997) Signal transduction from multiple Ras effectors. Curr. Biol., 7, 75-79.
-
(1997)
Curr. Biol.
, vol.7
, pp. 75-79
-
-
Katz, M.E.1
McCormick, F.2
-
31
-
-
0029890896
-
Oncogenic Ras activation of Raf/mitogen-activated protein kinase-independent pathways is sufficient to cause tumorigenic transformation
-
Khosravi-Far, R., White, M.A., Westwick, J.K., Solski, P.A., Chrzanowska-Wodnicka, M., Van Aelst, L., Wigler, M.H. and Der, C.J. (1996) Oncogenic Ras activation of Raf/mitogen-activated protein kinase-independent pathways is sufficient to cause tumorigenic transformation. Mol. Cell. Biol., 16, 3923-3933.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 3923-3933
-
-
Khosravi-Far, R.1
White, M.A.2
Westwick, J.K.3
Solski, P.A.4
Chrzanowska-Wodnicka, M.5
Van Aelst, L.6
Wigler, M.H.7
Der, C.J.8
-
32
-
-
0027986765
-
RalGDS family members interact with the effector loop of ras p21
-
Kikuchi, A., Demo, S.D., Ye, Z.H., Chen, Y.W. and Williams, L.T. (1994) ralGDS family members interact with the effector loop of ras p21. Mol. Cell. Biol., 14, 7483-7491.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 7483-7491
-
-
Kikuchi, A.1
Demo, S.D.2
Ye, Z.H.3
Chen, Y.W.4
Williams, L.T.5
-
33
-
-
0030723061
-
Identification and characterization of R-ras3: A novel member of the RAS gene family with a non-ubiquitous pattern of tissue distribution
-
Kimmelman, A., Tolkacheva, T., Lorenzi, M.V., Osada, M. and Chan, A.M. (1997) Identification and characterization of R-ras3: a novel member of the RAS gene family with a non-ubiquitous pattern of tissue distribution. Oncogene, 15, 2675-2685.
-
(1997)
Oncogene
, vol.15
, pp. 2675-2685
-
-
Kimmelman, A.1
Tolkacheva, T.2
Lorenzi, M.V.3
Osada, M.4
Chan, A.M.5
-
34
-
-
0031472912
-
Colocalization of Ras and Ral on the membrane is required for Ras-dependent Ral activation through Ral GDP dissociation stimulator
-
Kishida, S., Koyama, S., Matsubara, K., Kishida, M., Matsuura, Y. and Kikuchi, A. (1997) Colocalization of Ras and Ral on the membrane is required for Ras-dependent Ral activation through Ral GDP dissociation stimulator. Oncogene, 15, 2899-2907.
-
(1997)
Oncogene
, vol.15
, pp. 2899-2907
-
-
Kishida, S.1
Koyama, S.2
Matsubara, K.3
Kishida, M.4
Matsuura, Y.5
Kikuchi, A.6
-
35
-
-
0024600222
-
A ras-related gene with transformation suppressor activity
-
Kitayama, H., Sugimoto, Y., Matsuzaki, T., Ikawa, Y. and Noda, M. (1989) A ras-related gene with transformation suppressor activity. Cell, 56, 77-84.
-
(1989)
Cell
, vol.56
, pp. 77-84
-
-
Kitayama, H.1
Sugimoto, Y.2
Matsuzaki, T.3
Ikawa, Y.4
Noda, M.5
-
36
-
-
0031392796
-
Role of Crk oncogene product in physiologic signaling
-
Kiyokawa, E., Mochizuki, N., Kurata, T. and Matsuda, M. (1997) Role of Crk oncogene product in physiologic signaling. Crit. Rev. Oncogen., 8, 329-342.
-
(1997)
Crit. Rev. Oncogen.
, vol.8
, pp. 329-342
-
-
Kiyokawa, E.1
Mochizuki, N.2
Kurata, T.3
Matsuda, M.4
-
37
-
-
0030831143
-
Genetic interactions with Rap1 and Ras1 reveal a second function for the fat facets deubiquitinating enzyme in Drosophila eye development
-
Li, Q., Hariharan, I.K., Chen, F., Huang, Y. and Fischer, J.A. (1997) Genetic interactions with Rap1 and Ras1 reveal a second function for the fat facets deubiquitinating enzyme in Drosophila eye development. Proc. Natl Acad. Sci. USA, 94, 12515-12520.
-
(1997)
Proc. Natl Acad. Sci. USA
, vol.94
, pp. 12515-12520
-
-
Li, Q.1
Hariharan, I.K.2
Chen, F.3
Huang, Y.4
Fischer, J.A.5
-
39
-
-
0031037296
-
Linkage of G protein-coupled receptors to the MAPK signaling pathway through PI 3-kinase γ
-
Lopez-Ilasaca, M., Crespo, P., Pellici, P.G., Gutkind, J.S. and Wetzker, R. (1997) Linkage of G protein-coupled receptors to the MAPK signaling pathway through PI 3-kinase γ. Science, 275, 394-397.
-
(1997)
Science
, vol.275
, pp. 394-397
-
-
Lopez-Ilasaca, M.1
Crespo, P.2
Pellici, P.G.3
Gutkind, J.S.4
Wetzker, R.5
-
41
-
-
0030729777
-
Novel small GTPase M-Ras participates in reorganization of actin cytoskeleton
-
Matsumoto, K., Asuno, T. and Endo, T. (1997) Novel small GTPase M-Ras participates in reorganization of actin cytoskeleton. Oncogene, 15, 2409-2417.
-
(1997)
Oncogene
, vol.15
, pp. 2409-2417
-
-
Matsumoto, K.1
Asuno, T.2
Endo, T.3
-
42
-
-
0032582646
-
Activation of the Rap1 GTPase by the B cell antigen receptor
-
McLeod, S.J., Ingham, R.J., Bos, J.L., Kurosaki, T. and Gold, M.R. (1998) Activation of the Rap1 GTPase by the B cell antigen receptor. J. Biol. Chem., 273, 29218-29223.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 29218-29223
-
-
McLeod, S.J.1
Ingham, R.J.2
Bos, J.L.3
Kurosaki, T.4
Gold, M.R.5
-
43
-
-
0030113924
-
A mechanism of Bud1p GTPase action suggested by mutational analysis and immunolocalization
-
Michelitch, M. and Chant, J. (1996) A mechanism of Bud1p GTPase action suggested by mutational analysis and immunolocalization. Curr. Biol., 6, 446-454.
-
(1996)
Curr. Biol.
, vol.6
, pp. 446-454
-
-
Michelitch, M.1
Chant, J.2
-
44
-
-
0032531014
-
Activation of Rap1 in human neutrophils
-
M'Rabet, L., Coffer, P., Zwartkruis, F., Franke, B., Koenderman, L. and Bos, J.L. (1998) Activation of Rap1 in human neutrophils. Blood, 92, 2133-2140.
-
(1998)
Blood
, vol.92
, pp. 2133-2140
-
-
M'Rabet, L.1
Coffer, P.2
Zwartkruis, F.3
Franke, B.4
Koenderman, L.5
Bos, J.L.6
-
45
-
-
0030932843
-
Characterization of Ral GDP dissociation stimulator-like (RGL) activities to regulate c-fos promoter and the GDP/GTP exchange of Ral
-
Murai, H., Ikeda, M., Kishida, S., Ishida, O., Okazaki-Kishida, M., Matsuura, Y. and Kikuchi, A. (1997) Characterization of Ral GDP dissociation stimulator-like (RGL) activities to regulate c-fos promoter and the GDP/GTP exchange of Ral. J. Biol. Chem., 272, 10483-10490.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 10483-10490
-
-
Murai, H.1
Ikeda, M.2
Kishida, S.3
Ishida, O.4
Okazaki-Kishida, M.5
Matsuura, Y.6
Kikuchi, A.7
-
46
-
-
0027252544
-
Structure and function of Krev-1 transformation suppressor gene and its relatives
-
Noda, M. (1993) Structure and function of Krev-1 transformation suppressor gene and its relatives. Biochim. Biophys. Acta, 1155, 97-109.
-
(1993)
Biochim. Biophys. Acta
, vol.1155
, pp. 97-109
-
-
Noda, M.1
-
47
-
-
0030048696
-
Activation of B-raf protein kinase by Rap1B small GTP-binding protein
-
Ohtsuka, T., Shimizu, K., Yamamuri, B., Kuroda, S. and Takai, Y. (1996) Activation of B-raf protein kinase by Rap1B small GTP-binding protein. J. Biol. Chem., 271, 1258-1261.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 1258-1261
-
-
Ohtsuka, T.1
Shimizu, K.2
Yamamuri, B.3
Kuroda, S.4
Takai, Y.5
-
48
-
-
0032080085
-
Insulin regulates the dynamic balance between Ras and Rap1 signaling by coordinating the assembly states of the Grb2-SOS and CrkII-C3G complexes
-
Okada, S., Matsuda, M., Anafi, M., Pawson, T. and Pessin, J.E. (1998) Insulin regulates the dynamic balance between Ras and Rap1 signaling by coordinating the assembly states of the Grb2-SOS and CrkII-C3G complexes. EMBO J., 17, 2554-1265.
-
(1998)
EMBO J.
, vol.17
, pp. 2554-11265
-
-
Okada, S.1
Matsuda, M.2
Anafi, M.3
Pawson, T.4
Pessin, J.E.5
-
49
-
-
0027264558
-
BUD2 encodes a GTPase-activating protein for Bud1/Rsr1 necessary for proper bud-site selection in yeast
-
Park, H.O., Chant, J. and Herskowitz, I. (1993) BUD2 encodes a GTPase-activating protein for Bud1/Rsr1 necessary for proper bud-site selection in yeast. Nature, 365, 269-274.
-
(1993)
Nature
, vol.365
, pp. 269-274
-
-
Park, H.O.1
Chant, J.2
Herskowitz, I.3
-
50
-
-
0030940119
-
Two active states of the Ras-related Bud1/Rsr1 protein bind to different effectors to determine yeast cell polarity
-
Park, H.O., Bi, E., Pringle, J.R. and Herskowitz, I. (1997) Two active states of the Ras-related Bud1/Rsr1 protein bind to different effectors to determine yeast cell polarity. Proc. Natl Acad. Sci. USA, 94, 4463-4468.
-
(1997)
Proc. Natl Acad. Sci. USA
, vol.94
, pp. 4463-4468
-
-
Park, H.O.1
Bi, E.2
Pringle, J.R.3
Herskowitz, I.4
-
51
-
-
0028246501
-
Association of Rap1a and Rap1b proteins with late endocytic/phagocytic compartments and Rap2a with the Golgi complex
-
Pizon, V., Desjardins, M., Bucci, C., Parton, R.G. and Zerial, M. (1994) Association of Rap1a and Rap1b proteins with late endocytic/phagocytic compartments and Rap2a with the Golgi complex. J. Cell Sci., 107, 1661-1670.
-
(1994)
J. Cell Sci.
, vol.107
, pp. 1661-1670
-
-
Pizon, V.1
Desjardins, M.2
Bucci, C.3
Parton, R.G.4
Zerial, M.5
-
52
-
-
0028670126
-
The role of p21ras in receptor tyrosine kinase signalling
-
Pronk, G.J. and Bos, J.L. (1994) The role of p21ras in receptor tyrosine kinase signalling. Biochim. Biophys. Acta, 1198, 131-147.
-
(1994)
Biochim. Biophys. Acta
, vol.1198
, pp. 131-147
-
-
Pronk, G.J.1
Bos, J.L.2
-
53
-
-
0032570874
-
Costimulation through CD28 suppresses T cell receptor-dependent activation of the Ras-like small GTPase Rap1 in human T lymphocytes
-
Reedquist, K.A. and Bos, J.L. (1998) Costimulation through CD28 suppresses T cell receptor-dependent activation of the Ras-like small GTPase Rap1 in human T lymphocytes. J. Biol. Chem., 273, 4944-1949.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 4944-11949
-
-
Reedquist, K.A.1
Bos, J.L.2
-
54
-
-
0029990003
-
Activation of phosphoinositide 3-kinase by interaction with Ras and by point mutation
-
Rodriguez-Viciana, P., Warne, P.H., Vanhaesebroeck, B., Waterfield, M.D. and Downward., J. (1996) Activation of phosphoinositide 3-kinase by interaction with Ras and by point mutation. EMBO J., 15, 2442-2451.
-
(1996)
EMBO J.
, vol.15
, pp. 2442-2451
-
-
Rodriguez-Viciana, P.1
Warne, P.H.2
Vanhaesebroeck, B.3
Waterfield, M.D.4
Downward, J.5
-
55
-
-
0030911052
-
Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras
-
Rodriguez-Viciana, P., Warne, P.H., Khwaja, A., Marte, B.M., Pappin, D.J., Das, P., Waterfield, M.D., Ridley, A. and Downward, J. (1997) Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras. Cell, 89, 457-467.
-
(1997)
Cell
, vol.89
, pp. 457-467
-
-
Rodriguez-Viciana, P.1
Warne, P.H.2
Khwaja, A.3
Marte, B.M.4
Pappin, D.J.5
Das, P.6
Waterfield, M.D.7
Ridley, A.8
Downward, J.9
-
56
-
-
0030772378
-
The Ras-RasGAP complex: Structural basis for GTPase activation and its loss in oncogenic Ras mutants
-
Scheffzek, K., Ahmadian, M.R., Kabsch, W., Wiesmuller, L., Lautwein, A., Schmitz, F. and Wittinghofer, A. (1997) The Ras-RasGAP complex: structural basis for GTPase activation and its loss in oncogenic Ras mutants. Science, 277, 333-338.
-
(1997)
Science
, vol.277
, pp. 333-338
-
-
Scheffzek, K.1
Ahmadian, M.R.2
Kabsch, W.3
Wiesmuller, L.4
Lautwein, A.5
Schmitz, F.6
Wittinghofer, A.7
-
57
-
-
0030761145
-
Association of Krev-1/rap1a with Kritl, a novel ankyrin repeat-containing protein encoded by a gene mapping to 7q21-22
-
Serebriiskii, I., Estojak, J., Sonoda, G., Testa, J.R. and Golemis, E.A. (1997) Association of Krev-1/rap1a with Kritl, a novel ankyrin repeat-containing protein encoded by a gene mapping to 7q21-22. Oncogene, 15, 1043-1049.
-
(1997)
Oncogene
, vol.15
, pp. 1043-1049
-
-
Serebriiskii, I.1
Estojak, J.2
Sonoda, G.3
Testa, J.R.4
Golemis, E.A.5
-
58
-
-
0028577298
-
Identification of the guanine nucleotide dissociation stimulator for Ral as a putative effector molecule of R-ras, H-ras, K-ras and Rap
-
Spaargaren, M. and Bischoff, J.R. (1994) Identification of the guanine nucleotide dissociation stimulator for Ral as a putative effector molecule of R-ras, H-ras, K-ras and Rap. Proc. Natl Acad. Sci. USA, 91, 12609-12613.
-
(1994)
Proc. Natl Acad. Sci. USA
, vol.91
, pp. 12609-12613
-
-
Spaargaren, M.1
Bischoff, J.R.2
-
59
-
-
0029968827
-
Rho family GTPases: The cytoskeleton and beyond
-
Symons, M. (1996) Rho family GTPases: the cytoskeleton and beyond. Trends Biochem. Sci., 21, 178-181.
-
(1996)
Trends Biochem. Sci.
, vol.21
, pp. 178-181
-
-
Symons, M.1
-
60
-
-
0030022174
-
Ral-GTPases mediate a distinct downstream signaling pathway from Ras that facilitates cellular transformation
-
Urano, T., Emkey, R. and Feig, L.A. (1996) Ral-GTPases mediate a distinct downstream signaling pathway from Ras that facilitates cellular transformation. EMBO J., 15, 810-816.
-
(1996)
EMBO J.
, vol.15
, pp. 810-816
-
-
Urano, T.1
Emkey, R.2
Feig, L.A.3
-
61
-
-
0028977847
-
Receptor-tyrosine-kinase- And Gβγ-mediated MAP kinase activation by a common signalling pathway
-
van Biesen, T., Hawes, B.E., Luttrell, D.K., Krueger, K.M., Touhara, K., Porfiri, E., Sakaue, M., Luttrell, L.M. and Lefkowitz, R.J. (1995) Receptor-tyrosine-kinase- and Gβγ-mediated MAP kinase activation by a common signalling pathway. Nature, 376, 781-784.
-
(1995)
Nature
, vol.376
, pp. 781-784
-
-
Biesen, T.1
Hawes, B.E.2
Luttrell, D.K.3
Krueger, K.M.4
Touhara, K.5
Porfiri, E.6
Sakaue, M.7
Luttrell, L.M.8
Lefkowitz, R.J.9
-
62
-
-
0030793873
-
Biochemical characterization of C3G: An exchange factor that discriminates between Rap1 and Rap2 and is not inhibited by Rap1A (S17N)
-
van den Berghe, N., Cool, R.H., Horn, G. and Wittinghofer, A. (1997) Biochemical characterization of C3G: an exchange factor that discriminates between Rap1 and Rap2 and is not inhibited by Rap1A (S17N). Oncogene, 15, 845-850.
-
(1997)
Oncogene
, vol.15
, pp. 845-850
-
-
Van Den Berghe, N.1
Cool, R.H.2
Horn, G.3
Wittinghofer, A.4
-
63
-
-
0030963439
-
cAMP activates MAP kinase and Elk 1 through a B-raf- And Rap1-dependent pathway
-
Vossler, M.R., Yao, H., York, R.D., Pan, M.-G., Rim, S.M. and Stork, P.J.S. (1997) cAMP activates MAP kinase and Elk 1 through a B-raf- and Rap1-dependent pathway. Cell, 89, 74-82.
-
(1997)
Cell
, vol.89
, pp. 74-82
-
-
Vossler, M.R.1
Yao, H.2
York, R.D.3
Pan, M.-G.4
Rim, S.M.5
Stork, P.J.S.6
-
64
-
-
0030988723
-
Identification and characterization of a calmodulin-binding domain in Ral-A, a Ras-related GTP-binding protein purified from human erythrocyte membrane
-
Wang, K.L., Khan, M.T. and Roufogalis, B.D. (1997) Identification and characterization of a calmodulin-binding domain in Ral-A, a Ras-related GTP-binding protein purified from human erythrocyte membrane. J. Biol. Chem., 272, 16002-16009.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 16002-16009
-
-
Wang, K.L.1
Khan, M.T.2
Roufogalis, B.D.3
-
65
-
-
0028948382
-
Multiple Ras functions can contribute to mammalian cell transformation
-
White, M.A., Nicolette, C., Minden, A., Polverino, A., Van Aelst, L., Karin, M. and Wigler, M.H. (1995) Multiple Ras functions can contribute to mammalian cell transformation. Cell, 80, 533-541.
-
(1995)
Cell
, vol.80
, pp. 533-541
-
-
White, M.A.1
Nicolette, C.2
Minden, A.3
Polverino, A.4
Van Aelst, L.5
Karin, M.6
Wigler, M.H.7
-
66
-
-
0029950722
-
A role for the Ral guanine nucleotide dissociation stimulator in mediating Ras-induced transformation
-
White, M.A., Vale, T., Camonis, J.H., Schaefer, E. and Wigler, M.H. (1996) A role for the Ral guanine nucleotide dissociation stimulator in mediating Ras-induced transformation. J. Biol. Chem., 271, 16439-16442.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 16439-16442
-
-
White, M.A.1
Vale, T.2
Camonis, J.H.3
Schaefer, E.4
Wigler, M.H.5
-
67
-
-
0030464444
-
How Ras-related proteins talk to their effectors
-
Wittinghofer, A. and Nassar, N. (1996) How Ras-related proteins talk to their effectors. Trends Biochem. Sci., 21, 488-491.
-
(1996)
Trends Biochem. Sci.
, vol.21
, pp. 488-491
-
-
Wittinghofer, A.1
Nassar, N.2
-
68
-
-
0029831581
-
RalGDS-like factor (Rlf) is a novel Ras and Rap 1A-associating protein
-
Wolthuis, R.M., Bauer, B., van't Veer, L.J., de Vries-Smits, A.M., Cool, R.H., Spaargaren, M., Wittinghofer, A., Burgering, B.M. and Bos, J.L. (1996) RalGDS-like factor (Rlf) is a novel Ras and Rap 1A-associating protein. Oncogene, 13, 353-362.
-
(1996)
Oncogene
, vol.13
, pp. 353-362
-
-
Wolthuis, R.M.1
Bauer, B.2
Van't Veer, L.J.3
De Vries-Smits, A.M.4
Cool, R.H.5
Spaargaren, M.6
Wittinghofer, A.7
Burgering, B.M.8
Bos, J.L.9
-
69
-
-
0030728532
-
Stimulation of gene induction and growth by the Ras effector Rlf
-
Wolthuis, R.M.F., de Ruiter, N.D., Cool, R.H. and Bos, J.L. (1997) Stimulation of gene induction and growth by the Ras effector Rlf. EMBO J., 16, 6748-6761.
-
(1997)
EMBO J.
, vol.16
, pp. 6748-6761
-
-
Wolthuis, R.M.F.1
De Ruiter, N.D.2
Cool, R.H.3
Bos, J.L.4
-
70
-
-
0031944085
-
Activation of the small GTPase Ral in platelets
-
Wolthuis, R.M., Franke, B., van Triest, M., Bauer, B., Cool, R.H., Camonis, J.H., Akkerman, J.W. and Bos, J.L. (1998a) Activation of the small GTPase Ral in platelets. Mol. Cell. Biol., 18, 2486-2491.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 2486-2491
-
-
Wolthuis, R.M.1
Franke, B.2
Van Triest, M.3
Bauer, B.4
Cool, R.H.5
Camonis, J.H.6
Akkerman, J.W.7
Bos, J.L.8
-
71
-
-
0032499175
-
Ras-dependent activation of the small GTPase Ral
-
Wolthuis, R.M., Zwartkruis, F., Moen, T.C. and Bos, J.L. (1998b) Ras-dependent activation of the small GTPase Ral. Curr. Biol., 8, 471-474.
-
(1998)
Curr. Biol.
, vol.8
, pp. 471-474
-
-
Wolthuis, R.M.1
Zwartkruis, F.2
Moen, T.C.3
Bos, J.L.4
-
72
-
-
0031465736
-
An Eps homology (EH) domain protein that binds to the Ral-GTPase target, RalBP1
-
Yamaguchi, A., Urano, T., Goi, T. and Feig, L.A. (1997) An Eps homology (EH) domain protein that binds to the Ral-GTPase target, RalBP1. J. Biol. Chem., 272, 31230-31234.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 31230-31234
-
-
Yamaguchi, A.1
Urano, T.2
Goi, T.3
Feig, L.A.4
-
73
-
-
0032499282
-
Rap1 mediates sustained MAP kinase activation induced by nerve growth factor
-
York, R.D., Yao, H., Dillon, T., Ellig, C.L., Eckert, S.P., McCleskey, E.W. and Stork, P.J. (1998) Rap1 mediates sustained MAP kinase activation induced by nerve growth factor. Nature, 392, 622-626.
-
(1998)
Nature
, vol.392
, pp. 622-626
-
-
York, R.D.1
Yao, H.2
Dillon, T.3
Ellig, C.L.4
Eckert, S.P.5
McCleskey, E.W.6
Stork, P.J.7
-
74
-
-
0026656537
-
Microinjection of smg/rap1/Krev-1 p21 into Swiss 3T3 cells induces DNA synthesis and morphological chanses
-
Yoshida, Y., Kawata, M., Miura, Y., Musha, T., Sasaki, T., Kikuchi, A. and Takai, Y. (1992) Microinjection of smg/rap1/Krev-1 p21 into Swiss 3T3 cells induces DNA synthesis and morphological chanses. Mol. Cell. Biol., 12, 3407-3414.
-
(1992)
Mol. Cell. Biol.
, vol.12
, pp. 3407-3414
-
-
Yoshida, Y.1
Kawata, M.2
Miura, Y.3
Musha, T.4
Sasaki, T.5
Kikuchi, A.6
Takai, Y.7
-
75
-
-
0032531756
-
Extracellular signal-regulated activation of Rap1 fails to interfere in Ras effector signalling
-
Zwartkruis, F.J.T., Wolthuis, R.M.F., Nabben, N.M.J.M., Franke, B. and Bos, J.L. (1998) Extracellular signal-regulated activation of Rap1 fails to interfere in Ras effector signalling. EMBO J., 17, 5905-5912.
-
(1998)
EMBO J.
, vol.17
, pp. 5905-5912
-
-
Zwartkruis, F.J.T.1
Wolthuis, R.M.F.2
Nabben, N.M.J.M.3
Franke, B.4
Bos, J.L.5
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