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Volumn 17, Issue 12, 1997, Pages 7132-7138

The Ras-specific exchange factors mouse Sos1 (mSos1) and mSos2 are regulated differently: mSos2 contains ubiquitination signals absent in mSos1

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL TRANSFORMATION; CHIMERA; DROSOPHILA; GENE MAPPING; MOUSE; MYRISTYLATION; NEUROFIBROMATOSIS; NONHUMAN; PHENOTYPE; PLASMID; PRIORITY JOURNAL; PROTEIN ANALYSIS; SIGNAL TRANSDUCTION;

EID: 0030666849     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.17.12.7132     Document Type: Article
Times cited : (29)

References (53)
  • 1
    • 0027931640 scopus 로고
    • Membrane targeting of the nucleotide exchange factor Sos is sufficient for activating the Ras signaling pathway
    • Aronheim, A., U. Engelberg, N. X. Li, N. Al-Alawi, J. Schlessinger, and M. Karin. 1994. Membrane targeting of the nucleotide exchange factor Sos is sufficient for activating the Ras signaling pathway. Cell 78:949-961.
    • (1994) Cell , vol.78 , pp. 949-961
    • Aronheim, A.1    Engelberg, U.2    Li, N.X.3    Al-Alawi, N.4    Schlessinger, J.5    Karin, M.6
  • 2
    • 0028290777 scopus 로고
    • The Sos (son of sevenless) protein
    • Bar-Sagi, D. 1994. The Sos (son of sevenless) protein. Trends Endocrinol. Metab. 5:165-169.
    • (1994) Trends Endocrinol. Metab. , vol.5 , pp. 165-169
    • Bar-Sagi, D.1
  • 3
    • 0027732538 scopus 로고
    • Proteins regulating Ras and its relatives
    • Boguski, M. S., and F. McCormick. 1993. Proteins regulating Ras and its relatives. Nature 366:643-654.
    • (1993) Nature , vol.366 , pp. 643-654
    • Boguski, M.S.1    McCormick, F.2
  • 4
    • 0026627960 scopus 로고
    • Identification of murine homologues of the Drosophila son of sevenless gene - Potential activators of ras
    • Bowtell, D., P. Fu, M. Simon, and P. Senior. 1992. Identification of murine homologues of the Drosophila son of sevenless gene - potential activators of ras. Proc. Natl. Acad. Sci. USA 89:6511-6515.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 6511-6515
    • Bowtell, D.1    Fu, P.2    Simon, M.3    Senior, P.4
  • 5
    • 0027153103 scopus 로고
    • Epidermal growth factor regulates p21(Ras) through the formation of a complex of receptor, GRB2 adapter protein, and Sos nucleotide exchange factor
    • Buday, L., and J. Downward. 1993. Epidermal growth factor regulates p21(Ras) through the formation of a complex of receptor, GRB2 adapter protein, and Sos nucleotide exchange factor. Cell 73:611-620.
    • (1993) Cell , vol.73 , pp. 611-620
    • Buday, L.1    Downward, J.2
  • 6
    • 0028917954 scopus 로고
    • Regulation of ras-mediated signalling: More than one way to skin a cat
    • Burgering, B. M. T., and J. L. Bos. 1995. Regulation of ras-mediated signalling: more than one way to skin a cat. Trends Biochem. Sci. 20:18-22.
    • (1995) Trends Biochem. Sci. , vol.20 , pp. 18-22
    • Burgering, B.M.T.1    Bos, J.L.2
  • 7
    • 0027367141 scopus 로고
    • Regulated and constitutive activity by CDC25(Mm) (GRF), a Ras-specific exchange factor
    • Cen, H., A. G. Papageorge, W. C. Vass, K. Zhang, and D. R. Lowy. 1993. Regulated and constitutive activity by CDC25(Mm) (GRF), a Ras-specific exchange factor. Mol. Cell. Biol. 13:7718-7724.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 7718-7724
    • Cen, H.1    Papageorge, A.G.2    Vass, W.C.3    Zhang, K.4    Lowy, D.R.5
  • 8
    • 0026768072 scopus 로고
    • Isolation of multiple mouse cDNAs with coding homology to Saccharomyces cerevisiae CDC25 - Identification of a region related to bcr, vav, dbl and CDC24
    • Cen, H., A. G. Papageorge, R. Zippel, D. R. Lowy, and K. Zhang. 1992. Isolation of multiple mouse cDNAs with coding homology to Saccharomyces cerevisiae CDC25 - identification of a region related to bcr, vav, dbl and CDC24. EMBO J. 11:4007-4015.
    • (1992) EMBO J. , vol.11 , pp. 4007-4015
    • Cen, H.1    Papageorge, A.G.2    Zippel, R.3    Lowy, D.R.4    Zhang, K.5
  • 10
    • 0027198563 scopus 로고
    • Multiple ubiquitin-conjugating enzymes participate in the in vivo degradation of the yeast MATα2 repressor
    • Chen, P., P. Johnson, T. Sommer, S. Jentsch, and M. Hochstrasser. 1993. Multiple ubiquitin-conjugating enzymes participate in the in vivo degradation of the yeast MATα2 repressor. Cell 74:357-369.
    • (1993) Cell , vol.74 , pp. 357-369
    • Chen, P.1    Johnson, P.2    Sommer, T.3    Jentsch, S.4    Hochstrasser, M.5
  • 11
    • 0028205667 scopus 로고
    • Accumulation of p53 in a mutant cell line defective in the ubiquitin pathway
    • Chowdary, D. R., J. J. Dermody, K. K. Jha, and H. L. Ozer. 1994. Accumulation of p53 in a mutant cell line defective in the ubiquitin pathway. Mol. Cell. Biol. 14:1997-2003.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 1997-2003
    • Chowdary, D.R.1    Dermody, J.J.2    Jha, K.K.3    Ozer, H.L.4
  • 12
    • 0028018268 scopus 로고
    • The ubiquitin-proteasome proteolytic pathway
    • Ciechanover, A. 1994. The ubiquitin-proteasome proteolytic pathway. Cell 79:13-21.
    • (1994) Cell , vol.79 , pp. 13-21
    • Ciechanover, A.1
  • 14
    • 0026608178 scopus 로고
    • C. elegans cell-signalling gene sem-5 encodes a protein with SH2 and SH3 domains
    • Clark, S. G., M. J. Stern, and H. R. Horvitz. 1992. C. elegans cell-signalling gene sem-5 encodes a protein with SH2 and SH3 domains. Nature 356:340-344.
    • (1992) Nature , vol.356 , pp. 340-344
    • Clark, S.G.1    Stern, M.J.2    Horvitz, H.R.3
  • 15
    • 0025988293 scopus 로고
    • Degradation of p53 can be targetted by HPV E6 sequences distinct from those required for p53 binding and transactivation
    • Crook, T., J. A. Tidy, and K. H. Vousden. 1991. Degradation of p53 can be targetted by HPV E6 sequences distinct from those required for p53 binding and transactivation. Cell 67:547-556.
    • (1991) Cell , vol.67 , pp. 547-556
    • Crook, T.1    Tidy, J.A.2    Vousden, K.H.3
  • 16
  • 17
    • 0028216328 scopus 로고
    • Guanine-nucleotide exchange factors: A family of positive regulators of Ras and related GTPases
    • Feig, L. A. 1994. Guanine-nucleotide exchange factors: a family of positive regulators of Ras and related GTPases. Curr. Opin. Cell Biol. 6:204-211.
    • (1994) Curr. Opin. Cell Biol. , vol.6 , pp. 204-211
    • Feig, L.A.1
  • 18
    • 0024004720 scopus 로고
    • Purification of a RAS-responsive adenylyl cyclase complex from Saccharomyces cerevisiae by use of an epitope addition method
    • Field, J., J. Nikawa, D. Broek, B. MacDonald, L. Rodgers, I. A. Wilson, R. A. Lerner, and M. Wigler. 1988. Purification of a RAS-responsive adenylyl cyclase complex from Saccharomyces cerevisiae by use of an epitope addition method. Mol. Cell. Biol. 8:2159-2165.
    • (1988) Mol. Cell. Biol. , vol.8 , pp. 2159-2165
    • Field, J.1    Nikawa, J.2    Broek, D.3    MacDonald, B.4    Rodgers, L.5    Wilson, I.A.6    Lerner, R.A.7    Wigler, M.8
  • 19
    • 85036678474 scopus 로고    scopus 로고
    • Personal communication
    • Frech, M., and P. Chardin. Personal communication.
    • Frech, M.1    Chardin, P.2
  • 20
    • 0026089183 scopus 로고
    • Cyclin is degraded by the ubiquitin pathway
    • Glotzer, M., A. W. Murray, and M. W. Kirschner. 1991. Cyclin is degraded by the ubiquitin pathway. Nature 349:132-138.
    • (1991) Nature , vol.349 , pp. 132-138
    • Glotzer, M.1    Murray, A.W.2    Kirschner, M.W.3
  • 21
    • 0023798826 scopus 로고
    • Two dominant-acting selectable markers for gene transfer studies in mammalian cells
    • Hartman, S. C., and R. C. Mulligan. 1988. Two dominant-acting selectable markers for gene transfer studies in mammalian cells. Proc. Natl. Acad. Sci. USA 85:8047-8051.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 8047-8051
    • Hartman, S.C.1    Mulligan, R.C.2
  • 23
    • 0029131894 scopus 로고
    • The cellular content of Cdc25p, the Ras exchange factor in Saccharomyces cerevisiae, is regulated by destabilization through a cyclin destruction box
    • Kaplon, T., and M. Jacquet. 1995. The cellular content of Cdc25p, the Ras exchange factor in Saccharomyces cerevisiae, is regulated by destabilization through a cyclin destruction box. J. Biol. Chem. 270:20742-20747.
    • (1995) J. Biol. Chem. , vol.270 , pp. 20742-20747
    • Kaplon, T.1    Jacquet, M.2
  • 24
    • 0028800305 scopus 로고
    • Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for ras transformation
    • Khosravi-Far, R., P. A. Solski, G. J. Clark, M. S. Kinch, and C. J. Der. 1995. Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for ras transformation. Mol. Cell. Biol. 15:6443-6453.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 6443-6453
    • Khosravi-Far, R.1    Solski, P.A.2    Clark, G.J.3    Kinch, M.S.4    Der, C.J.5
  • 25
    • 0022552131 scopus 로고
    • Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eucaryotic ribosomes
    • Kozak, M. 1986. Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eucaryotic ribosomes. Cell 77:273-292.
    • (1986) Cell , vol.77 , pp. 273-292
    • Kozak, M.1
  • 26
  • 28
    • 0025930898 scopus 로고
    • Both cyclin AΔ60 and BΔ97 are stable and arrest cells in M-phase, but only cyclin BΔ97 turns on cyclin destruction
    • Luca, F. C., E. K. Shibuya, C. E. Dohrmann, and J. V. Ruderman. 1991. Both cyclin AΔ60 and BΔ97 are stable and arrest cells in M-phase, but only cyclin BΔ97 turns on cyclin destruction. EMBO J. 10:4311-4320.
    • (1991) EMBO J. , vol.10 , pp. 4311-4320
    • Luca, F.C.1    Shibuya, E.K.2    Dohrmann, C.E.3    Ruderman, J.V.4
  • 29
    • 0021683127 scopus 로고
    • Monoclonal antibodies specific for the carboxy terminus of simian virus 40 large antigen
    • MacArthur, H., and G. Walter. 1984. Monoclonal antibodies specific for the carboxy terminus of simian virus 40 large antigen. J. Virol. 52:483-491.
    • (1984) J. Virol. , vol.52 , pp. 483-491
    • MacArthur, H.1    Walter, G.2
  • 30
    • 0028872649 scopus 로고
    • Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation
    • Marshall, C. J. 1995. Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation. Cell 80:179-185.
    • (1995) Cell , vol.80 , pp. 179-185
    • Marshall, C.J.1
  • 31
    • 0028825531 scopus 로고
    • Ras target proteins in eukaryotic cells
    • Marshall, M. S. 1995. Ras target proteins in eukaryotic cells. FASEB J. 9:1311-1318.
    • (1995) FASEB J. , vol.9 , pp. 1311-1318
    • Marshall, M.S.1
  • 32
    • 0026523616 scopus 로고
    • Cloning by functional complementation of a mouse cDNA encoding a homologue of CDC25, a Saccharomyces cerevisiae RAS activator
    • Martegani, E., M. Vanoni, R. Zippel, P. Coccetti, R. Brambilla, C. Ferrari, E. Sturani, and L. Alberghina. 1992. Cloning by functional complementation of a mouse cDNA encoding a homologue of CDC25, a Saccharomyces cerevisiae RAS activator. EMBO J. 11:2151-2157.
    • (1992) EMBO J. , vol.11 , pp. 2151-2157
    • Martegani, E.1    Vanoni, M.2    Zippel, R.3    Coccetti, P.4    Brambilla, R.5    Ferrari, C.6    Sturani, E.7    Alberghina, L.8
  • 33
    • 0027263157 scopus 로고
    • A role for the ubiquitin-dependent proteolytic pathway in MHC class I-restricted antigen presentation
    • Michalek, M. T., E. P. Grant, C. Gramm, A. L. Goldberg, and K. L. Rock. 1993. A role for the ubiquitin-dependent proteolytic pathway in MHC class I-restricted antigen presentation. Nature 363:552-554.
    • (1993) Nature , vol.363 , pp. 552-554
    • Michalek, M.T.1    Grant, E.P.2    Gramm, C.3    Goldberg, A.L.4    Rock, K.L.5
  • 34
    • 0040624512 scopus 로고
    • Generation of protein-reactive antibodies by short peptides is an event of high frequency: Implications for the structural basis of immune recognition
    • Niman, H. L., R. A. Houghten, L. E. Walker, R. A. Reisfeld, I. A. Wilson, J. M. Hogle, and R. A. Lerner. 1983. Generation of protein-reactive antibodies by short peptides is an event of high frequency: implications for the structural basis of immune recognition. Proc. Natl. Acad. Sci. USA 80:4949-4953.
    • (1983) Proc. Natl. Acad. Sci. USA , vol.80 , pp. 4949-4953
    • Niman, H.L.1    Houghten, R.A.2    Walker, L.E.3    Reisfeld, R.A.4    Wilson, I.A.5    Hogle, J.M.6    Lerner, R.A.7
  • 36
    • 0025916625 scopus 로고
    • Conserved structural motifs in cyclins identified by sequence analysis
    • Nugent, J. H. A., C. E. Alfa, T. Young, and J. S. Hyams. 1991. Conserved structural motifs in cyclins identified by sequence analysis. J. Cell Sci. 99: 669-674.
    • (1991) J. Cell Sci. , vol.99 , pp. 669-674
    • Nugent, J.H.A.1    Alfa, C.E.2    Young, T.3    Hyams, J.S.4
  • 37
    • 0027468233 scopus 로고
    • A Drosophila SH2-SH3 adaptor protein implicated in coupling the sevenless tyrosine kinase to an activator of Ras guanine nucleotide exchange
    • Olivier, J. P., T. Raabe, M. Henkemeyer, B. Dickson, G. Mbamalu, B. Margolis, J. Schlessinger, E. Hafen, and T. Pawson. 1993. A Drosophila SH2-SH3 adaptor protein implicated in coupling the sevenless tyrosine kinase to an activator of Ras guanine nucleotide exchange. Sos. Cell 73:179-191.
    • (1993) Sos. Cell , vol.73 , pp. 179-191
    • Olivier, J.P.1    Raabe, T.2    Henkemeyer, M.3    Dickson, B.4    Mbamalu, G.5    Margolis, B.6    Schlessinger, J.7    Hafen, E.8    Pawson, T.9
  • 39
    • 0027980321 scopus 로고
    • Ubiquitin and the proteasome are required for processing the NF-κB1 precursor and the activation of NF-εB
    • Palombella, V. J., O. J. Rando, A. L. Goldberg, and T. Maniatis. 1994. Ubiquitin and the proteasome are required for processing the NF-κB1 precursor and the activation of NF-εB. Cell 78:773-785.
    • (1994) Cell , vol.78 , pp. 773-785
    • Palombella, V.J.1    Rando, O.J.2    Goldberg, A.L.3    Maniatis, T.4
  • 40
    • 0027458572 scopus 로고
    • Cell surface control of the multiubiquitination and deubiquitination of high-affinity immunoglobulin e receptors
    • Paolini, R., and J.-P. Kinet. 1993. Cell surface control of the multiubiquitination and deubiquitination of high-affinity immunoglobulin E receptors. EMBO J. 12:779-786.
    • (1993) EMBO J. , vol.12 , pp. 779-786
    • Paolini, R.1    Kinet, J.-P.2
  • 41
    • 0028903247 scopus 로고
    • An essential role for Rac in Ras transformation
    • Qiu, R. G., J. Chen, D. Kirn, F. McCormick, and M. Symons. 1995. An essential role for Rac in Ras transformation. Nature 374:457-459.
    • (1995) Nature , vol.374 , pp. 457-459
    • Qiu, R.G.1    Chen, J.2    Kirn, D.3    McCormick, F.4    Symons, M.5
  • 42
    • 0027999033 scopus 로고
    • Membrane-targeting potentiates guanine nucleotide exchange factor CDC25 and SOS1 activation of Ras transforming activity
    • Quilliam, L. A., S. Y. Huff, K. M. Rabun, W. Wei, W. Park, D. Broek, and C. J. Der. 1994. Membrane-targeting potentiates guanine nucleotide exchange factor CDC25 and SOS1 activation of Ras transforming activity. Proc. Natl. Acad. Sci. USA 91:8512-8516.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 8512-8516
    • Quilliam, L.A.1    Huff, S.Y.2    Rabun, K.M.3    Wei, W.4    Park, W.5    Broek, D.6    Der, C.J.7
  • 43
    • 0027980319 scopus 로고
    • Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules
    • Rock, K. L., C. Gramm, L. Rothstein, K. Clark, R. Stein, L. Dick, D. Hwang, and A. L. Goldberg. 1994. Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules. Cell 78:761-771.
    • (1994) Cell , vol.78 , pp. 761-771
    • Rock, K.L.1    Gramm, C.2    Rothstein, L.3    Clark, K.4    Stein, R.5    Dick, L.6    Hwang, D.7    Goldberg, A.L.8
  • 45
    • 0027358723 scopus 로고
    • The HPV-16 E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53
    • Scheffner, M., J. M. Huibregtse, R. D. Vierstra, and P. M. Howley. 1993. The HPV-16 E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53. Cell 75:495-505.
    • (1993) Cell , vol.75 , pp. 495-505
    • Scheffner, M.1    Huibregtse, J.M.2    Vierstra, R.D.3    Howley, P.M.4
  • 46
    • 0025639158 scopus 로고
    • The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53
    • Scheffner, M., B. A. Werness, J. M. Huibregtse, A. J. Levine, and P. M. Howley. 1990. The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53. Cell 63:1129-1136.
    • (1990) Cell , vol.63 , pp. 1129-1136
    • Scheffner, M.1    Werness, B.A.2    Huibregtse, J.M.3    Levine, A.J.4    Howley, P.M.5
  • 47
    • 0028967267 scopus 로고
    • Role of a ubiquitin-conjugating enzyme in degradation of S- And M-phase cyclins
    • Seufert, W., B. Futcher, and S. Jentsch. 1995. Role of a ubiquitin-conjugating enzyme in degradation of S-and M-phase cyclins. Nature 373:78-81.
    • (1995) Nature , vol.373 , pp. 78-81
    • Seufert, W.1    Futcher, B.2    Jentsch, S.3
  • 48
    • 0026659515 scopus 로고
    • Molecular cloning of cDNAs encoding a guanine-nucleotide-releasing factor for Ras p21
    • Shou, C., C. L. Farnsworth, B. G. Neel, and L. A. Feig. 1992. Molecular cloning of cDNAs encoding a guanine-nucleotide-releasing factor for Ras p21. Nature 358:351-354.
    • (1992) Nature , vol.358 , pp. 351-354
    • Shou, C.1    Farnsworth, C.L.2    Neel, B.G.3    Feig, L.A.4
  • 49
    • 0025997867 scopus 로고
    • Ras1 and a putative guanine nucleotide exchange factor perform crucial steps in signaling by the sevenless protein tyrosine kinase
    • Simon, M. A., D. D. L. Bowtell, G. S. Dodson, T. R. Laverty, and G. M. Rubin. 1991. Ras1 and a putative guanine nucleotide exchange factor perform crucial steps in signaling by the sevenless protein tyrosine kinase. Cell 67:701-716.
    • (1991) Cell , vol.67 , pp. 701-716
    • Simon, M.A.1    Bowtell, D.D.L.2    Dodson, G.S.3    Laverty, T.R.4    Rubin, G.M.5
  • 50
    • 0028027308 scopus 로고
    • Ubiquitin-dependent c-Jun degradation in vivo is mediated by the δ domain
    • Treier, M., L. M. Staszewski, and D. Bohmann. 1994. Ubiquitin-dependent c-Jun degradation in vivo is mediated by the δ domain. Cell 78:787-798.
    • (1994) Cell , vol.78 , pp. 787-798
    • Treier, M.1    Staszewski, L.M.2    Bohmann, D.3
  • 53
    • 0029132697 scopus 로고
    • Differential interactions of human Sos1 and Sos2 with Grb2
    • Yang, S., L. Van Aelst, and D. Bar-Sagi. 1995. Differential interactions of human Sos1 and Sos2 with Grb2. J. Biol. Chem. 270:18212-18215.
    • (1995) J. Biol. Chem. , vol.270 , pp. 18212-18215
    • Yang, S.1    Van Aelst, L.2    Bar-Sagi, D.3


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