-
3
-
-
33748237378
-
A total synthesis of taxol
-
J.J. Master, J.T. Link, L.B. Snyder, W.B. Young and S.J. Danishefsky, A total synthesis of taxol. Angew. Chem. (Int. Edn.) 34 (1995) 1723-1726.
-
(1995)
Angew. Chem. (Int. Edn.)
, vol.34
, pp. 1723-1726
-
-
Master, J.J.1
Link, J.T.2
Snyder, L.B.3
Young, W.B.4
Danishefsky, S.J.5
-
4
-
-
0028353983
-
First total synthesis of taxol. 2. Completion of the C and D rings
-
R.A. Holton, H. Kim, C. Somoza, F. Linag, J. Biediger et al., First total synthesis of taxol. 2. Completion of the C and D rings. J. Am. Chem. Soc. 116 (1994) 1599-1600.
-
(1994)
J. Am. Chem. Soc.
, vol.116
, pp. 1599-1600
-
-
Holton, R.A.1
Kim, H.2
Somoza, C.3
Linag, F.4
Biediger, J.5
-
5
-
-
0028012837
-
Total synthesis of taxol
-
K.C. Nicolau, Z. Yang, J.J. Liu, H. Ueno, P.G. Nauternet and R.K. Guy, Total synthesis of taxol. Nature 367 (1994) 630-634.
-
(1994)
Nature
, vol.367
, pp. 630-634
-
-
Nicolau, K.C.1
Yang, Z.2
Liu, J.J.3
Ueno, H.4
Nauternet, P.G.5
Guy, R.K.6
-
6
-
-
0027420977
-
Is cremophor, solvent for paclitaxel, cytotoxic?
-
M.-L. Fjallskog, L. Frii and J. Bergh, Is cremophor, solvent for paclitaxel, cytotoxic? Lancet 342 (1993) 876.
-
(1993)
Lancet
, vol.342
, pp. 876
-
-
Fjallskog, M.-L.1
Frii, L.2
Bergh, J.3
-
7
-
-
0027228024
-
Clinical toxicities encountered with paclitaxel (Taxol)
-
E.K. Rowinsky, E.A. Eisenhauer, V. Chaudry, S.G. Arbuck and R.C. Donehower, Clinical toxicities encountered with paclitaxel (Taxol). Semin. Oncol. 20 (1993) 1-15.
-
(1993)
Semin. Oncol.
, vol.20
, pp. 1-15
-
-
Rowinsky, E.K.1
Eisenhauer, E.A.2
Chaudry, V.3
Arbuck, S.G.4
Donehower, R.C.5
-
8
-
-
0025326680
-
Hypersensitivity reactions from taxol
-
R.B. Weiss, R.C. Donehower, P.H. Wiernik, T. Ohnuma, R.L. Gralla, D. Trump, J.R. Baker, D.A. VanEcho, D.D. VonHoff and B. Leyland-Jones, Hypersensitivity reactions from taxol. J. Clin. Oncol. 8 (1990) 1263-1268.
-
(1990)
J. Clin. Oncol.
, vol.8
, pp. 1263-1268
-
-
Weiss, R.B.1
Donehower, R.C.2
Wiernik, P.H.3
Ohnuma, T.4
Gralla, R.L.5
Trump, D.6
Baker, J.R.7
Vanecho, D.A.8
Vonhoff, D.D.9
Leyland-Jones, B.10
-
10
-
-
0027137936
-
Antitumoral effect of taxol-containing liposomes in a taxol-resistant murine tumor model
-
A. Sharma, E. Mayhew and R.M. Straubingen, Antitumoral effect of taxol-containing liposomes in a taxol-resistant murine tumor model. Cancer Res. 53 (1993) 5877-5881.
-
(1993)
Cancer Res.
, vol.53
, pp. 5877-5881
-
-
Sharma, A.1
Mayhew, E.2
Straubingen, R.M.3
-
11
-
-
0028838372
-
Pharmaceutical and physical properties of paclitaxel (taxol) complexes with cyclodextrins
-
A. Sharma, S.V. Balasubramianian and R.M. Straubingen, Pharmaceutical and physical properties of paclitaxel (taxol) complexes with cyclodextrins. J. Pharm. Sci. 84 (1995) 1223-1230.
-
(1995)
J. Pharm. Sci.
, vol.84
, pp. 1223-1230
-
-
Sharma, A.1
Balasubramianian, S.V.2
Straubingen, R.M.3
-
12
-
-
0028919413
-
Interaction of taxol and other anticancer drugs with α-cyclodextrin
-
T. Cserhati, E. Forgacs and J. Hollo, Interaction of taxol and other anticancer drugs with α-cyclodextrin. J. Pharm. Biomed. Anal. 13 (1995) 533-541.
-
(1995)
J. Pharm. Biomed. Anal.
, vol.13
, pp. 533-541
-
-
Cserhati, T.1
Forgacs, E.2
Hollo, J.3
-
13
-
-
0028280464
-
A mixed micellar formulation suitable for the parenteral administration of taxol
-
H. Alkan-Onyuksel, S. Ramakrishnan, H.-B. Chai and J.M. Pezzuto, A mixed micellar formulation suitable for the parenteral administration of taxol. Pharm. Res. 11 (1994) 206-212.
-
(1994)
Pharm. Res.
, vol.11
, pp. 206-212
-
-
Alkan-Onyuksel, H.1
Ramakrishnan, S.2
Chai, H.-B.3
Pezzuto, J.M.4
-
14
-
-
0030071043
-
Drug delivery systems: water soluble taxol 2′-poly(ethylene glycol) ester prodrugs-design and in vivo effectiveness
-
R.B. Greenwald, C.W. Gilbert, A. Pendri, C.D. Conover, J. Xia and A. Martinez, Drug delivery systems: water soluble taxol 2′-poly(ethylene glycol) ester prodrugs-design and in vivo effectiveness. J. Med. Chem. 39 (1996) 424-431.
-
(1996)
J. Med. Chem.
, vol.39
, pp. 424-431
-
-
Greenwald, R.B.1
Gilbert, C.W.2
Pendri, A.3
Conover, C.D.4
Xia, J.5
Martinez, A.6
-
15
-
-
0026926609
-
Conjugates of anticancer agents and polymers: advantages of macromolecular therapeutics in vivo
-
H. Maeda, L.W. Seymour and Y. Miyamoto, Conjugates of anticancer agents and polymers: advantages of macromolecular therapeutics in vivo. Bioconj. Chem. 3 (1992) 351-361.
-
(1992)
Bioconj. Chem.
, vol.3
, pp. 351-361
-
-
Maeda, H.1
Seymour, L.W.2
Miyamoto, Y.3
-
16
-
-
0028878938
-
Problems of delivery of monoclonal antibodies
-
R.M. Reilly, J. Sandhu, T.M. Alvarez-Diez, S. Gallinger, J. Kirsh and H. Stern, Problems of delivery of monoclonal antibodies. Clin. Pharmacokinet. 28 (1995) 126-142.
-
(1995)
Clin. Pharmacokinet.
, vol.28
, pp. 126-142
-
-
Reilly, R.M.1
Sandhu, J.2
Alvarez-Diez, T.M.3
Gallinger, S.4
Kirsh, J.5
Stern, H.6
-
17
-
-
0026529567
-
Preparation and characterization of a water soluble dextran immunoconjugate of doxorubicin and the monoclonal antibody (ABL 364)
-
Z. Brich, S. Ravel, T. Kissel, J. Fritsch and A. Schoffmann, Preparation and characterization of a water soluble dextran immunoconjugate of doxorubicin and the monoclonal antibody (ABL 364). J. Control. Release 19 (1992) 245-258.
-
(1992)
J. Control. Release
, vol.19
, pp. 245-258
-
-
Brich, Z.1
Ravel, S.2
Kissel, T.3
Fritsch, J.4
Schoffmann, A.5
-
18
-
-
0009692303
-
Pre-clinical therapy of human melanoma with morpholino-doxorubicin conjugated to a monoclonal antibody directed against an integrin on melanoma cells
-
B.M. Mueller, R.A. Reisfeld, M.H. Silveira, J.D. Duncan and W.A. Wrasidlo, Pre-clinical therapy of human melanoma with morpholino-doxorubicin conjugated to a monoclonal antibody directed against an integrin on melanoma cells. Antibody Immunoconj. Radiopharm. 4 (1991) 99-104.
-
(1991)
Antibody Immunoconj. Radiopharm.
, vol.4
, pp. 99-104
-
-
Mueller, B.M.1
Reisfeld, R.A.2
Silveira, M.H.3
Duncan, J.D.4
Wrasidlo, W.A.5
-
19
-
-
0029017965
-
Therapeutic efficacy of a doxorubicin immunoconjugate in a preclinical model of spontaneuos metastatic human melanoma
-
G.P. Sivam, P.J. Martin, R.A. Reisfeld and B.M. Mueller, Therapeutic efficacy of a doxorubicin immunoconjugate in a preclinical model of spontaneuos metastatic human melanoma. Cancer Res. 55 (1995) 2352-2355.
-
(1995)
Cancer Res.
, vol.55
, pp. 2352-2355
-
-
Sivam, G.P.1
Martin, P.J.2
Reisfeld, R.A.3
Mueller, B.M.4
-
20
-
-
0002079949
-
Disposition and tumor localization of mitomycin C-dextran conjugates in mice
-
Y. Takakura, A. Takagi, M. Hashida and H. Sezaki, Disposition and tumor localization of mitomycin C-dextran conjugates in mice. Pharm. Res. 4 (1987) 293-300.
-
(1987)
Pharm. Res.
, vol.4
, pp. 293-300
-
-
Takakura, Y.1
Takagi, A.2
Hashida, M.3
Sezaki, H.4
-
21
-
-
0025014962
-
Physiological barriers to delivery of monoclonal antibodies and other macromolecules in tumors
-
R.K. Jain, Physiological barriers to delivery of monoclonal antibodies and other macromolecules in tumors. Cancer Res. 50 (1990) 814S-819S.
-
(1990)
Cancer Res.
, vol.50
-
-
Jain, R.K.1
-
22
-
-
0343825564
-
Vascular endothelial barrier function and its regulation
-
In: K.L. Audus and T.J. Raub (Eds.) Plenum Press, N.Y.
-
A.B. Malik and A. Siflinger-Birnboim, Vascular endothelial barrier function and its regulation. In: K.L. Audus and T.J. Raub (Eds.), Biological barriers to protein delivery. Plenum Press, N.Y., 1993, pp. 231-245.
-
(1993)
Biological Barriers to Protein Delivery
, pp. 231-245
-
-
Malik, A.B.1
Siflinger-Birnboim, A.2
-
23
-
-
0026757191
-
Drug-polymer conjugates: potential for improved chemotherapy
-
R. Duncan, Drug-polymer conjugates: potential for improved chemotherapy. Anti-Cancer Drugs 3 (1992) 175-210.
-
(1992)
Anti-Cancer Drugs
, vol.3
, pp. 175-210
-
-
Duncan, R.1
-
24
-
-
0027987791
-
Polymer conjugates, pharmacokinetic considerations for design and development
-
R. Duncan and F. Spreafico, Polymer conjugates, pharmacokinetic considerations for design and development. Clin. Pharmacokinet. 27 (1994) 290-306.
-
(1994)
Clin. Pharmacokinet.
, vol.27
, pp. 290-306
-
-
Duncan, R.1
Spreafico, F.2
-
25
-
-
0027816261
-
Bovine serum albumin-doxorubicin conjugate overcomes multidrug resistence in rat hepatoma
-
K. Ohkwada, T. Hatano, K. Yamada, K. Joh, Y. Tsukada and M. Matsuda, Bovine serum albumin-doxorubicin conjugate overcomes multidrug resistence in rat hepatoma. Cancer Res. 53 (1993) 4238-4242.
-
(1993)
Cancer Res.
, vol.53
, pp. 4238-4242
-
-
Ohkwada, K.1
Hatano, T.2
Yamada, K.3
Joh, K.4
Tsukada, Y.5
Matsuda, M.6
-
27
-
-
0022858683
-
A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent Smancs
-
Y. Matsumura and H. Maeda, A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent Smancs. Cancer Res. 46 (1986) 6387-6392.
-
(1986)
Cancer Res.
, vol.46
, pp. 6387-6392
-
-
Matsumura, Y.1
Maeda, H.2
-
28
-
-
0014094610
-
Transport of cytostatic agents by plasma proteins. Penetration of serum albumin into tumor cells
-
J.C. Cerrottini and H. Isliker, Transport of cytostatic agents by plasma proteins. Penetration of serum albumin into tumor cells. Eur. J. Cancer. 3 (1967) 111-124.
-
(1967)
Eur. J. Cancer.
, vol.3
, pp. 111-124
-
-
Cerrottini, J.C.1
Isliker, H.2
-
29
-
-
0017336288
-
High molecular weight derivatives of methotrexate as chemotherapeutic agents
-
B.C.F. Chu and J.M. Whiteley, High molecular weight derivatives of methotrexate as chemotherapeutic agents. Mol. Pharmacol. 13 (1977) 80-88.
-
(1977)
Mol. Pharmacol.
, vol.13
, pp. 80-88
-
-
Chu, B.C.F.1
Whiteley, J.M.2
-
30
-
-
0014949207
-
Cleavage of structural proteins during the assembly of the head of batteriophage T4
-
U.K. Laemmli, Cleavage of structural proteins during the assembly of the head of batteriophage T4. Nature, 227 (1970) 680-685.
-
(1970)
Nature
, vol.227
, pp. 680-685
-
-
Laemmli, U.K.1
-
31
-
-
0014067578
-
Preparation of enzimatically active, water insoluble derivatives of trypsin
-
A.F.S.A. Habeeb, Preparation of enzimatically active, water insoluble derivatives of trypsin. Arch. Biochem. Biophys. 119 (1967) 264-268.
-
(1967)
Arch. Biochem. Biophys.
, vol.119
, pp. 264-268
-
-
Habeeb, A.F.S.A.1
-
32
-
-
0013889689
-
Determination of free amino groups in proteins by trinitrobenzene sulfonic acid
-
A.F.S.A. Habeeb, Determination of free amino groups in proteins by trinitrobenzene sulfonic acid. Anal. Biochem. 14 (1966) 328-336.
-
(1966)
Anal. Biochem.
, vol.14
, pp. 328-336
-
-
Habeeb, A.F.S.A.1
-
34
-
-
0020483282
-
Role of thiols in degradation of proteins by cathepsins
-
T. Kooistra, P.C. Millard and J.B. Lloyd, Role of thiols in degradation of proteins by cathepsins. Biochem. J. 204 (1982) 471-477.
-
(1982)
Biochem. J.
, vol.204
, pp. 471-477
-
-
Kooistra, T.1
Millard, P.C.2
Lloyd, J.B.3
-
35
-
-
0028244947
-
Reverse-phase high-performance liquid chromatographic determination of taxol in mouse plasma
-
A. Sharma, W.D. Conway and R.M. Straubinger, Reverse-phase high-performance liquid chromatographic determination of taxol in mouse plasma. J Chrom. B. 655 (1994) 315-319.
-
(1994)
J Chrom. B.
, vol.655
, pp. 315-319
-
-
Sharma, A.1
Conway, W.D.2
Straubinger, R.M.3
-
36
-
-
0027762115
-
Stability problems with taxol in mouse plasma during analysis by liquid chromatography
-
J. Leslie, J.M. Kujawa, N. Eddington, M. Egorin and J. Eiseman, Stability problems with taxol in mouse plasma during analysis by liquid chromatography. J. Pharm. Biomed. Anal. 11 (1993) 1349-1352.
-
(1993)
J. Pharm. Biomed. Anal.
, vol.11
, pp. 1349-1352
-
-
Leslie, J.1
Kujawa, J.M.2
Eddington, N.3
Egorin, M.4
Eiseman, J.5
-
38
-
-
0343780920
-
-
US Patent 5,362,831, 1994
-
N. Mongelli, E. Pesenti, A. Suarato and G. Biasioli, Polymer-bound paclitaxel derivatives. US Patent 5,362,831, 1994.
-
Polymer-bound Paclitaxel Derivatives
-
-
Mongelli, N.1
Pesenti, E.2
Suarato, A.3
Biasioli, G.4
-
39
-
-
0025099302
-
The potential of water soluble polymeric carriers in targeted and site specific drug delivery
-
J. Kopecek, The potential of water soluble polymeric carriers in targeted and site specific drug delivery. J. Control. Release 11 (1990) 279-290.
-
(1990)
J. Control. Release
, vol.11
, pp. 279-290
-
-
Kopecek, J.1
-
40
-
-
0023261546
-
Phase I clinical and pharmacokinetic study of taxol
-
P.H. Wiernik, E.L. Scwartz, J.J. Strauman, J.P. Dutcher, R.B. Lipton and E. Paietta, Phase I clinical and pharmacokinetic study of taxol. Cancer Res. 47 (1987) 2486-2493.
-
(1987)
Cancer Res.
, vol.47
, pp. 2486-2493
-
-
Wiernik, P.H.1
Scwartz, E.L.2
Strauman, J.J.3
Dutcher, J.P.4
Lipton, R.B.5
Paietta, E.6
-
41
-
-
0025966501
-
Pharmacokinetics of methotrexate after iv infusion of methotrexate-rabbit serum albumin conjugate to rabbits
-
E.J. Yoon, H.W. Chang, M.G. Lee, H. Lee, M.K. Park and C.K. Kim, Pharmacokinetics of methotrexate after iv infusion of methotrexate-rabbit serum albumin conjugate to rabbits. Int. J. Pharm. 67 (1991) 177-182.
-
(1991)
Int. J. Pharm.
, vol.67
, pp. 177-182
-
-
Yoon, E.J.1
Chang, H.W.2
Lee, M.G.3
Lee, H.4
Park, M.K.5
Kim, C.K.6
-
42
-
-
0026185431
-
Properties of mitomycin C-albumin conjugates in vitro and in vivo
-
T. Tanaka, Y. Kaneo and S. Iguchi, Properties of mitomycin C-albumin conjugates in vitro and in vivo. Bioconj. Chem. 2 (1991) 261-269.
-
(1991)
Bioconj. Chem.
, vol.2
, pp. 261-269
-
-
Tanaka, T.1
Kaneo, Y.2
Iguchi, S.3
-
43
-
-
0025092855
-
Preparation and properties of mitomycin C-albumin conjugate
-
Y. Kaneo, T. Tanaka and S. Iguchi, Preparation and properties of mitomycin C-albumin conjugate. Chem. Pharm. Bull. 38 (1990) 2614-2616.
-
(1990)
Chem. Pharm. Bull.
, vol.38
, pp. 2614-2616
-
-
Kaneo, Y.1
Tanaka, T.2
Iguchi, S.3
-
44
-
-
0022516737
-
Drug targeting in antiviral chemoterapy
-
L. Fiume, B. Bassi, C. Busi, A. Mattioli and G. Spinosa, Drug targeting in antiviral chemoterapy. Biochem. Pharmacol. 35 (1986) 967-972.
-
(1986)
Biochem. Pharmacol.
, vol.35
, pp. 967-972
-
-
Fiume, L.1
Bassi, B.2
Busi, C.3
Mattioli, A.4
Spinosa, G.5
-
45
-
-
0005149430
-
In vitro evaluation of immunoconjugates prepared by linking mitomyvin C to monoclonal antibodies via polyglutamic acid carriers
-
R.S. Greenfield, P.D. Senter, A.T. Daues, K.A. Fitzgerald, S. Gawlak, W. Manger and G.R. Braslawsy, In vitro evaluation of immunoconjugates prepared by linking mitomyvin C to monoclonal antibodies via polyglutamic acid carriers. Antibody, Immunoconj. Radiopahrm. 2 (1989) 201-209.
-
(1989)
Antibody, Immunoconj. Radiopahrm.
, vol.2
, pp. 201-209
-
-
Greenfield, R.S.1
Senter, P.D.2
Daues, A.T.3
Fitzgerald, K.A.4
Gawlak, S.5
Manger, W.6
Braslawsy, G.R.7
-
46
-
-
0026978878
-
Enhanced antitumor activity of daunomycin conjugated with antigastric cancer monoclonal antibody MGb2
-
S. Li, X. Zhang, T. Qiao, X. Chen, S. Zhang and L. Chen, Enhanced antitumor activity of daunomycin conjugated with antigastric cancer monoclonal antibody MGb2. Oncol. Res. 4 (1992) 447-453.
-
(1992)
Oncol. Res.
, vol.4
, pp. 447-453
-
-
Li, S.1
Zhang, X.2
Qiao, T.3
Chen, X.4
Zhang, S.5
Chen, L.6
-
47
-
-
0029093035
-
Enhancement of the selectivity and antitumor efficacy of a CC-1065 analogue through immunoconjugate formation
-
R.V.J. Chari, K.A. Jackel, L.A. Bourret, S.M. Derr, B.M. Tadayoni, K.M. Mattocks, S.A. Shah, C. Liu, W.A. Blattler and V.S. Goldmacher, Enhancement of the selectivity and antitumor efficacy of a CC-1065 analogue through immunoconjugate formation. Cancer Res. 55 (1995) 4079-4084.
-
(1995)
Cancer Res.
, vol.55
, pp. 4079-4084
-
-
Chari, R.V.J.1
Jackel, K.A.2
Bourret, L.A.3
Derr, S.M.4
Tadayoni, B.M.5
Mattocks, K.M.6
Shah, S.A.7
Liu, C.8
Blattler, W.A.9
Goldmacher, V.S.10
-
48
-
-
0023809123
-
Microtubule changes and cytotoxicity in leukemic cell lines treated with taxol
-
E.K. Rowinsky, R.C. Donehower, R.J. Jones and R.W. Tucker, Microtubule changes and cytotoxicity in leukemic cell lines treated with taxol. Cancer Res. 48 (1988) 4093-4100.
-
(1988)
Cancer Res.
, vol.48
, pp. 4093-4100
-
-
Rowinsky, E.K.1
Donehower, R.C.2
Jones, R.J.3
Tucker, R.W.4
-
49
-
-
0027249114
-
Current dosage and schedule issues in the development of paclitaxel (Taxol)
-
S.G. Arbuck, G. Canetta, N. Onetto and M.C. Christian, Current dosage and schedule issues in the development of paclitaxel (Taxol). Semin. Oncol. 20(3), (1993) Suppl. 3, 31-39.
-
(1993)
Semin. Oncol.
, vol.20
, Issue.3 SUPPL. 3
, pp. 31-39
-
-
Arbuck, S.G.1
Canetta, G.2
Onetto, N.3
Christian, M.C.4
|