Controlled DNA delivery systems

Pharmaceutical Research

Volumn 16, Issue 8, 1999, Pages 1300-1308

  Luo, Dan ^a   Woodrow Mumford, Kim ^a   Belcheva, Nadya ^a   Saltzman, W Mark ^a  

^a Cornell University   (United States)

Author keywords

Controlled release; DNA; EVAc; Microsphere; PLA; PLGA

Indexed keywords

ACETIC ACID DERIVATIVE; BACTERIOPHAGE DNA; DNA VACCINE; DOUBLE STRANDED DNA; GREEN FLUORESCENT PROTEIN; POLYGLACTIN; POLYLACTIDE;

AGAR GEL ELECTROPHORESIS; ARTICLE; BIOCOMPATIBILITY; CONTROLLED DRUG RELEASE; DIFFUSION COEFFICIENT; DRUG COST; DRUG DEGRADATION; DRUG DELIVERY SYSTEM; DRUG IMPLANTATION; ENCAPSULATION; FLUORESCENCE ANALYSIS; GENE TARGETING; PRIORITY JOURNAL;

BIODEGRADATION, ENVIRONMENTAL; CAPSULES; CHEMISTRY, PHARMACEUTICAL; DNA; DRUG CARRIERS; GENE TRANSFER TECHNIQUES; LACTIC ACID; MICROSPHERES; POLYESTERS; POLYGLYCOLIC ACID; POLYMERS; POLYVINYLS;

EID: 0032837486     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1014870102295     Document Type: Article

References (30)

1. 1. J. A. Wolff, R. W. Malone, P. Williams, W. Chong, G. Acsadi, A. Jani, and P. L. Felgner. Direct gene transfer into mouse muscle in vivo. Science 47:1465-1468 (1990).
2. 2. J. J. Donnelly, J. B. Ulmer, J. W. Shiver, and M. A. Liu. DNA vaccines. Annu. Rev. Immunol. 15:617-648 (1997).
3. 3. W. F. Anderson. Human gene therapy. Nature 392:25-30 (1998).
4. 4. R. G. Crystal. Transfer of genes to humans: early lessons and obstacles to success. Science 270:404-410 (1995).
5. 5. S. K. Tripathy, H. B. Black, E. Goldwasser, and J. M. Leiden. Immune responses to transgene-encoded proteins limit the stability of gene expression after injection of replication-defective adenovirus vectors. Nat. Med. 2:545-550 (1996).
6. 6. A. R. Thierry, P. Rabinovich, B. Peng, L. C. Mahan, J. L. Bryant, and R. C. Gallo. Characterization of liposome-mediated gene delivery: expression, stability and pharmacokinetics of plasmid DNA. Gene Ther. 4:226-237 (1997).
7. 7. Y. Liu, D. Liggitt, W. Zhong, G. Tu, K. Gaensler, and R. Debs. Cationic liposome-mediated intravenous gene delivery. J Biol. Chem. 270:24864-24870 (1995).
8. 8. N. Ishii, J. Fukushima, T. Kaneko, E. Okada, K. Tani, S. I. Tanaka, K. Hamajima, K. Q. Xin, S. Kawamoto, W. Koff, K. Nishioka, T. Yasuda, and K. Okuda. Cationic liposomes are a strong adjuvant for a DNA vaccine of human immunodeficiency virus type 1. AIDS Res. Hum. Retroviruses 13:1421-1428 (1997).
9. 9. P. Erbacher, S. Zou, T. Bettinger, A. M. Steffan, and J. S. Remy. Chitosan-based vector/DNA complexes for gene delivery: biophysical characteristics and transfection ability [In Process Citation]. Pharm. Res. 15:1332-1339 (1998).
10. 10. P. Erbacher, A. C. Roche, M. Monsigny, and P. Midoux. The reduction of the positive charges of polylysine by partial gluconoylation increases the transfection efficiency of polylysine/DNA complexes. Biochim. Biophys. Acta 1324:27-36 (1997).
11. 11. J. E. Murphy, T. Uno, J. D. Hamer, F. E. Cohen, V. Dwarki, and R. N. Zuckermann. A combinatorial approach to the discovery of efficient cationic peptoid reagents for gene delivery. Proc. Natl. Acad. Sci. U S A 95:1517-1522 (1998).
12. 12. E. F. Fynan, R. G. Webster, D. H. Fuller, J. R. Haynes, J. C. Santoro, and H. L. Robinson. DNA vaccines: protective immunizations by parenteral, mucosal, and gene-gun inoculations. Proc. Natl. Acad. Sci. U S A 90:11478-11482 (1993).
13. 13. S. L. Hart, R. P. Harbottle, R. Cooper, A. Miller, R. Williamson, and C. Coutelle. Gene delivery and expression mediated by an integrin-binding peptide Gene Ther. 2:552-554 (1995).
14. 14. S. Katayose, and K. Kataoka. Water-soluble polyion complex associates of DNA and poly(ethylene glycol)-poly(L-lysine) block copolymer. Bioconjug. Chem. 8:702-707 (1997).
15. 15. J. S. Kim, B. I. Kim, A. Maruyama, T. Akaike, and S. W. Kim. A new non-viral DNA delivery vector: the terplex system. J. Contr. Rel. 53:175-182 (1998).
16. 16. M. J. Mahoney, and W. M. Saltzman. Controlled release of proteins to tissue transplants for the treatment of neurodegenerative disorders. J. Pharm. Sci. 85:1276-1281 (1996).
17. 17. S. Cohen, T. Yoshioka, M. Lucarelli, L. Hwang, and R. Langer. Controlled delivery systems for proteins based on poly(lactic/ glycolic acid) microspheres. Pharm. Res. 8:713-720 (1991).
18. 18. W. M. Saltzman, and R. Langer. Transport rates of proteins in porous materials with known microgeometry. Biophys. J. 55:163-171 (1989).
19. 19. R. Siegel, and R. Langer. Controlled Release of Polypeptides and Other Macromolecules. Pharm. Res.:2-10 (1984).
20. 20. E. Mathiowitz, J. S. Jacob, Y. S. Jong, G. P. Carino, D. E. Chickering, P. Chaturvedi, C. A. Santos, K. Vijayaraghavan, S. Montgomery, M. Bassett, and C. Morrell. Biologically erodable microspheres as potential oral drug delivery systems. Nature 386:410-414 (1997).
21. 21. Y. S. Jong, J. S. Jacob, K. P. Yip, G. Gardner, E. Seitelman, M. Whitney, S. Montgomery, and E. Mathiowitz. Controlled release of plasmid DNA. J. Contr. Rel. 47:123-134 (1997).
22. 22. V. Labhasetwar, J. Bonadio, S. Goldstein, W. Chen, and R. J. Levy. A DNA controlled-release coating for gene transfer: transfection in skeletal and cardiac muscle. J. Pharm. Sci. 87:1347-1350 (1998).
23. 23. D. Wang, D. R. Robinson, G. S. Kwon, and J. Samuel. Encapsulation of plasmid DNA in biodegradable poly(D, L-lactic-co-glycolic acid) microspheres as a novel approach for immunogene delivery. J. Contr. Rel. 57:9-18 (1999).
24. 24. S. Ando, D. Putnam, D. W. Pack, and R. Langer. PLGA microspheres containing plasmid DNA: preservation of supercoiled DNA via cryopreparation and carbohydrate stabilization. J. Pharm. Sci. 88:126-130 (1999).
25. 25. C. E. Beaty, and W. M. Saltzman. Controlled growth factor delivery induces differental neurite outgrowth in three-dimensional cell cultures. J. Contr. Rel. 24:15-23 (1993).
26. 26. D. H. Jones, S. Corris, S. McDonald, J. C. Clegg, and G. H. Farrar. Poly(DL-lactide-co-glycolide)-encapsulated plasmid DNA elicits systemic and mucosal antibody responses to encoded protein after oral administration. Vaccine 15:814-817 (1997).
27. 27. C. E. Krewson, R. Dause, M. Mak, and W. M. Saltzman. Stabilization of nerve growth factor in controlled release polymers and in tissue. J. Biomater. Sci. Polym. Ed. 8:103-117 (1996).
28. 28. R. Langer, and J. Folkman. Polymers for the sustained release of proteins and other macromolecules. Nature 263:797-800 (1976).
29. 29. W. Dang, and W. M. Saltzman. Dextran retention in the rat brain following release from a polymer implant. Biotechnol. Prog. 8:527-532 (1992).
30. 30. K. Soda, and A. Wada. Dynamic Light-Scattering Studies on Thermal Motions of Native DNAs In Solution. Biophys. Chem. 20:185-200 (1984).