DNA vaccines - Designer vaccines for the 21st century

New England Journal of Medicine

Volumn 341, Issue 4, 1999, Pages 277-278

  Seder, Robert A ^a   Gurunathan, Sanjay ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA VACCINE;

ANTIBODY PRODUCTION; ARTICLE; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNE RESPONSE; INFECTION PREVENTION; LEISHMANIASIS; NONHUMAN; PRIORITY JOURNAL; TUBERCULOSIS;

ANIMALS; HUMANS; IMMUNITY, CELLULAR; VACCINATION; VACCINES, DNA;

EID: 0033595134     PISSN: 00284793     EISSN: None     Source Type: Journal    
DOI: 10.1056/NEJM199907223410410     Document Type: Article

References (5)

1. McDonnell WM, Askari FK. DNA vaccines. N Engl J Med 1996;334: 42-5.
2. Wang R, Doolan DL, Le TP, et al. Induction of antigen-specific cytotoxic T lymphocytes in humans by a malaria DNA vaccine. Science 1998; 282:476-80.
3. Klinman DM, Yi AK, Beaucage SL, Conover J, Krieg AM CpG motifs present in bacteria DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon gamma. Proc Natl Acad Sci U S A 1996; 93:2879-83.
4. Roman M, Martin-Orozco E, Goodman JS, ct al. Immunostimulatory DNA sequences function as T helper-1-promoting adjuvants. Nat Med 1997;3:849-54.
5. Roy K, Mao HQ, Huang SK, Leong KW. Oral gene delivery with chitosan - DNA nanoparticles generates immunologic protection in a murine model of peanut allergy. Nat Med 1999;5:387-91.