Chrysamine-G, a lipophilic analogue of congo red, inhibits Aβ-induced toxicity in PC12 cells

Life Sciences

Volumn 63, Issue 20, 1998, Pages 1807-1814

  Klunk, William E ^a,c   Debnath, Manik L ^a   Koros, Aurelia M C ^b   Pettegrew, Jay W ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b GRADUATE SCHOOL OF PUBLIC HEALTH   (United States)

^c UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

Alzheimer's disease; Beta amyloid; Chrysamine G; Congo red; PC12 cells

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; AMYLOID BETA PROTEIN; CHRYSAMINE G; CONGO RED; DRUG DERIVATIVE; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; CELL STRAIN; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; NONHUMAN; PROTEIN BINDING; RAT;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; ANIMALS; BENZOATES; BIPHENYL COMPOUNDS; COLORING AGENTS; CONGO RED; DRUG ANTAGONISM; HUMANS; PC12 CELLS; RATS;

ANIMALIA;

EID: 0032500717     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0024-3205(98)00454-8     Document Type: Article

References (45)

1. 1. C. BEHL, J. DAVIS, G.M. COLE and D. SCHUBERT, Biochem.Biophys.Res.Commun. 186 944-950 (1992).
2. 2. M.P. MATTSON, B. CHENG, D. DAVIS, K. BRYANT, I. LIEBERBURG and R.E. RYDEL, J.Neurosci. 12 376-389 (1992).
3. 3. M.S. SHEARMAN, C.I. RAGAN and L.L. IVERSEN, Proc.Natl.Acad.Sci.U.S.A. 91 1470-1474 (1994).
4. 4. B.A. YANKNER, L.K. DUFFY and D.A. KIRSCHNER, Science 250 279-282 (1990).
5. 5. A. LORENZO and B.A. YANKNER, Proc.Natl.Acad.Sci.U.S.A. 91 12243-12247 (1994).
6. 6. L.K. SIMMONS, P.C. MAY, K.J. TOMASELLI, R.E. RYDEL, K.S. FUSON, E.F. BRIGHAM, S. WRIGHT, I. LIEBERBURG, G.W. BECKER, D.N. BREMS and ET AL, Molecular Pharmacology 45 373-379 (1994).
7. 7. M.P. MATTSON, K.J. TOMASELLI and R.E. RYDEL, Brain Res. 621 35-49 (1993).
8. 8. C.J. PIKE, D. BURDICK, A.J. WALENCEWICZ, G.G. GLABE and C.W. COTMAN, Journal of Neuroscience 13 1676-1687 (1993).
9. 9. C.J. PIKE, A.J. WALENCEWICZ, C.G. GLABE and C.W. COTMAN, Brain Res. 563 311-314 (1991).
10. 10. M.C. BURGEVIN, M. PASSAT, N. DANIEL, M. CAPET and A. DOBLE, Neuroreport 5 2429-2432 (1994).
11. 11. S.J. POLLACK, I.I. SADLER, S.R. HAWTIN, V.J. TAILOR and M.S. SHEARMAN, Neurosci.Lett. 184 113-116 (1995).
12. 12. W.E. KLUNK, M.L. DEBNATH and J.W. PETTEGREW, Neurobiol.Aging 15 691-698 (1994).
13. 13. S.J. POLLACK, I.I. SADLER, S.R. HAWTIN, V.J. TAILOR and M.S. SHEARMAN, Neurosci.Lett. 95 211-214 (1995).
14. 14. M.B. PODLISNY, B.L. OSTASZEWSKI, S.L. SQUAZZO, E.H. KOO, R.E. RYDELL, D.B. TEPLOW and D.J. SELKOE, Journal of Biological Chemistry 270 9564-9570 (1995).
15. 15. A.E. ROHER, M.O. CHANEY, Y.M. KUO, S.D. WEBSTER, W.B. STINE, L.J. HAVERKAMP, A.S. WOODS, R.J. COTTER, J.M. TUOHY, G.A. KRAFFT, B.S. BONNELL and M.R. EMMERLING, Journal of Biological Chemistry 96 20631-20635 (1996).
16. 16. W.E. KLUNK, J.W. PETTEGREW and D.J. ABRAHAM, J.Histochem.Cytochem. 37 1273-1281 (1989).
17. 17. W.E. KLUNK, M.L. DEBNATH and J.W. PETTEGREW, Neurobiol.Aging 15 691-698 (1994).
18. 18. M. TUBIS, W.H. BLAHD and R.A. NORDYKE, J.Am.Pharmaceut.Assoc. 49 422-425 (1960).
19. 19. W.E. KLUNK, M.L. DEBNATH and J.W. PETTEGREW, Neurobiol.Aging 16 541-548 (1995).
20. 20. M.B. HANSEN, S.E. NIELSEN and K. BERG, J.Immunol.Methods 119 203-210 (1989).
21. 21. C. BEHL, J.B. DAVIS, R. LESLEY and D. SCHUBERT, Cell 77 817-827 (1994).
22. 22. S.D. YAN, X. CHEN, J. FU, M. CHEN, H. ZHU, A. ROHER, T. SLATTERY, L. ZHAO, M. NAGASHIMA, J. MORSER, A. MIGHELI, P. NAWROTH, D. STERN and A.M. SCHMIDT, Nature 96 685-691 (1996).
23. 23. T. TOMIYAMA, S. ASANO, Y. SUWA, T. MORITA, K. KATAOKA, H. MORI and N. ENDO, Biochem.Biophys.Res.Commun. 204 76-83 (1994).
24. 24. J.N. KELLER, Z. PANG, J.W. GEDDES, J.G. BEGLEY, A. GERMEYER, G. WAEG and M.P. MATTSON, J.Neurochem. 97 273-284 (1997).
25. 25. D.R. HOWLETT, K.H. JENNINGS, D.C. LEE, M.S. CLARK, F. BROWN, R. WETZEL, S.J. WOOD, P. CAMILLERI and G.W. ROBERTS, Neurodegeneration 4 23-32 (1995).
26. 26. J.P. BENNETT and H.I. YAMAMURA, Neurotransmitter receptor binding, H.I. Yamamura, S.J. Enna and M.J. Kuhar (eds), 61-89, Raven Press, New York (1985).
27. 27. F. WIRTZ-BRUGGER AND A. GIOVANNI, Soc.Neurosci.Abstr. 23 1627(1997).
28. 28. W.J. PORTER, J.E. AUDIA, L.N. BOGGS, J.J. DROSTE, K.S. FUSON, P.A. HYSLOP, T. JOHNSON AND-P.C. MAY, Amer.Chem.Soc.215th National Mtg, Div.Med.Chem.Abst. 212(1998).
29. 29. J.Y. KOH, L.L. YANG and C.W. COTMAN, Brain Res. 533 315-320 (1990).
30. 30. K. HENSLEY, D.A. BUTTERFIELD, M. MATTSON, M. AKSENOVA, M. HARRIS, J.F. WU, R. FLOYD and J. CARNEY, Proceedings of the Western Pharmacology Society 95;38 113-120 (1995).
31. 31. D.A. BUTTERFIELD, K. HENSLEY, M. HARRIS, M. MATTSON and J. CARNEY, Biochem.Biophys.Res.Commun. 200 710-715 (1994).
32. 32. H. JIANG, D. BURDICK, C.G. GLABE, C.W. COTMAN and A.J. TENNER, Journal of Immunology 152 5050-5059 (1994).
33. 33. J. ROGERS, J. SCHULTZ, L. BRACHOVA, L.F. LUE, S. WEBSTER, B. BRADT, N.R. COOPER and D.E. MOSS, Research in Immunology 143 624-630 (1992).
34. 34. J. EL KHOURY, S.E. HICKMAN, C.A. THOMAS, L. CAO, S.C. SILVERSTEIN and J.D. LOIKE, Nature 96 716-719 (1996).
35. 35. Z. ZHANG, R.E. RYDEL, G.J. DRZEWIECKI, K. FUSON, S. WRIGHT, M. WOGULIS, J.E. AUDIA, P.C. MAY and P.A. HYSLOP, J.Neurochem. 96 1595-1606 (1996).
36. 36. M.E. HARRIS, K. HENSLEY, D.A. BUTTERFIELD, R.A. LEEDLE and J.M. CARNEY, Experimental Neurology 131 193-202 (1995).
37. 37. S.W. BARGER, D. HORSTER, K. FURUKAWA, Y. GOODMAN, J. KRIEGLSTEIN and M.P. MATTSON, Proc.NatLAcad.Sci.U.S.A. 92 9328-9332 (1995).
38. 38. Y. SAGARA, R. DARGUSCH, F.G. KLIER, D. SCHUBERT and C. BEHL, Journal of Neuroscience 96 497-505 (1996).
39. 39. Y. GOODMAN and M.P. MATTSON, J.Neurochem. 96 869-872 (1996).
40. 40. R.J. MARK, M.A. LOVELL, W.R. MARKESBERY, K. UCHIDA and M.P. MATTSON, J.Neurochem. 97 255-264 (1997).
41. 41. A.J. BRUCE, B. MALFROY and M. BAUDRY, Proc.Natl.Acad.Sci.U.S.A. 96 2312-2316 (1996).
42. 42. M.F. WALTER, W.E. KLUNK, A. GIOVANNI AND-R.P. MASON, Soc.Neurosci.Abstr. 23 1663(1997).
43. 43. M.R. EMMERLING, K. SPIEGEL and M.D. WATSON, Immunopharmacology 38 101-109 (1997).
44. 44. A. LORENZO, B. RAZZABONI, G.G. WEIR and B.A. YANKNER, Nature 368 756-760 (1994).
45. 45. I.I. SADLER, D.W. SMITH, M.S. SHEARMAN, C.I. RAGAN, V.J. TAILOR and S.J. POLLACK, Neuroreport 95 49-53 (1995).