Kinetic properties of dihydrofolate reductase from wild-type and mutant Plasmodium vivax expressed in Escherichia coli

Molecular and Biochemical Parasitology

Volumn 113, Issue 2, 2001, Pages 241-249

  Tahar, Rachida ^a   De Pécoulas, Philippe Eldin ^a   Basco, Leonardo K ^a,b   Chiadmi, Mohammed ^a   Mazabraud, André ^a,c  

^a CNRS   (France)

^b Inst de Rech Agric Pour Le Devmt   (Cameroon)

^c UNIVERSITÉ PARIS SACLAY   (France)

Author keywords

Drug resistance; Malaria; Plasmodium falciparum; Pyrimethamine

Indexed keywords

CYCLOGUANIL; DIHYDROFOLATE REDUCTASE; FOLIC ACID ANTAGONIST; METHOTREXATE; PROGUANIL; PYRIMETHAMINE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; TRIMETHOPRIM;

ANALYTIC METHOD; ARTICLE; DRUG EFFECT; ENZYME ACTIVITY; ENZYME DENATURATION; ENZYME INHIBITION; ENZYME KINETICS; ENZYME PURIFICATION; ESCHERICHIA COLI; PLASMODIUM VIVAX; POINT MUTATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; RENATURATION;

ANIMALS; CLONING, MOLECULAR; DRUG RESISTANCE; ESCHERICHIA COLI; FOLIC ACID ANTAGONISTS; KINETICS; PLASMODIUM VIVAX; PYRIMETHAMINE; RECOMBINANT PROTEINS; TETRAHYDROFOLATE DEHYDROGENASE;

ESCHERICHIA COLI; PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX;

EID: 0035815313     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-6851(01)00230-4     Document Type: Article

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